0001035443false00010354432026-01-262026-01-26

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
 

FORM 8-K

CURRENT REPORT
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): January 26, 2026


ALEXANDRIA REAL ESTATE EQUITIES, INC.
(Exact name of registrant as specified in its charter)

Maryland1-1299395-4502084
(State or other jurisdiction of
incorporation)
(Commission File Number)(I.R.S. Employer Identification No.)

 26 North Euclid Avenue, Pasadena, California 91101
(Address of principal executive offices) (Zip code)

Registrant’s telephone number, including area code: (626) 578-0777
 
N/A
(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

            Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

            Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

           Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

            Pre-commencement communications pursuant to Rule 13e-4 (c) under the Exchange Act (17 CFR 240.13e-4 (c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each classTrading Symbol(s)Name of each exchange on which registered
Common Stock, $0.01 par value per share
ARE
New York Stock Exchange

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.




Item 2.02.  Results of Operations and Financial Condition.

On January 26, 2026, Alexandria Real Estate Equities, Inc. (the “Company”) issued a press release entitled “Alexandria Real Estate Equities, Inc. Reports Fourth Quarter and Year Ended December 31, 2025 Financial and Operating Results.”  The press release referred to certain supplemental information that is available on the Company’s website at www.are.com.  A copy of the press release and supplemental information are attached hereto as Exhibit 99.1.

The information contained in this Item 2.02, including the exhibit referenced herein, is being furnished and shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that section.  Such information shall not be incorporated by reference into any filing under the Securities Act of 1933, as amended (the “Securities Act”), or the Exchange Act, whether made before or after the date hereof, regardless of any general incorporation language in such filing.

Item 9.01.  Financial Statements and Exhibits.

(d)  Exhibits.

99.1     Alexandria Real Estate Equities, Inc.’s Earnings Press Release and Supplemental Information for the Fourth Quarter and Year Ended December 31, 2025

104 Cover Page Interactive Data File (embedded within the Inline XBRL document)

Forward-Looking Statements

This current report on Form 8-K contains forward-looking statements within the meaning of Section 27A of the Securities Act, and Section 21E of the Exchange Act.  These statements include words such as “forecast,” “guidance,” “goals,” “projects,” “estimates,” “anticipates,” “believes,” “expects,” “intends,” “may,” “plans,” “seeks,” “should,” “targets,” or “will,” or the negative of these words or similar words.  Forward-looking statements involve certain risks and uncertainties, and actual results may differ materially from those discussed in each such statement.  A number of important factors could cause actual results to differ materially from those included within or contemplated by the forward-looking statements, including, but not limited to, the factors described in the Company’s filings with the Securities and Exchange Commission, including the Company’s most recent annual report on Form 10-K and any subsequent quarterly reports on Form 10-Q.  The Company does not undertake any responsibility to update any of these factors or to announce publicly any revisions to any of the forward-looking statements contained in this or any other document, whether as a result of new information, future events, or otherwise.



SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
ALEXANDRIA REAL ESTATE EQUITIES, INC.
January 26, 2026By:/s/ Joel S. Marcus
Joel S. Marcus
Executive Chairman
By:/s/ Peter M. Moglia
Peter M. Moglia
Chief Executive Officer and
Chief Investment Officer
By:/s/ Marc E. Binda
Marc E. Binda
Chief Financial Officer and Treasurer

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Table of Contents
December 31, 2025
COMPANY HIGHLIGHTS
Page
Page
Alexandria's Mission and Cluster Model ..............................................
EARNINGS PRESS RELEASE
Fourth Quarter and Year Ended December 31, 2025 Financial and
Operating Results ................................................................................
Consolidated Statements of Operations ..........................................
Guidance ...................................................................................................
Consolidated Balance Sheets ............................................................
Dispositions and Sales of Partial Interests ..........................................
SUPPLEMENTAL INFORMATION
Company Profile .......................................................................................
External Growth / Investments in Real Estate
Investor Information .................................................................................
Investments in Real Estate ................................................................
Financial and Asset Base Highlights .....................................................
New Class A/A+ Development and Redevelopment Properties:
High-Quality and Diverse Client Base .................................................
Recent Deliveries ...........................................................................
Internal Operating Metrics
Current Projects ..............................................................................
Key Operating Metrics .............................................................................
Summary of Pipeline ......................................................................
Same Property Performance ..................................................................
Construction Spending ........................................................................
Leasing Activity .........................................................................................
Capitalization of Interest .....................................................................
Contractual Lease Expirations ...............................................................
Joint Venture Financial Information ...................................................
Top 20 Tenants .........................................................................................
Balance Sheet Management
Summary of Properties and Occupancy ..............................................
Investments ..........................................................................................
Property Listing ........................................................................................
Balance Sheet ......................................................................................
Key Credit Metrics ...............................................................................
Summary of Debt .................................................................................
Definitions and Reconciliations
Definitions and Reconciliations ..........................................................
CONFERENCE CALL
INFORMATION:
Tuesday, January 27, 2026
2:00 p.m. Eastern Time
11:00 a.m. Pacific Time
(833) 366-1125 or
(412) 902-6738
Ask to join the conference call for
Alexandria Real Estate Equities, Inc.
CONTACT INFORMATION:
Alexandria Real Estate Equities, Inc.
corporateinformation@are.com
JOEL S. MARCUS
Executive Chairman &
Founder
PETER M. MOGLIA
Chief Executive Officer &
Chief Investment Officer
MARC E. BINDA
Chief Financial Officer &
Treasurer
PAULA SCHWARTZ
Managing Director,
Rx Communications Group
(917) 633-7790
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ALEXANDRIA’S
PATH FORWARD
Maintain a Strong and
Flexible Balance Sheet,
Significant Liquidity,
and Targeted Leverage
Continue to Successfully
Manage G&A
Maintain Optionality for
Future Growth Focused on
Megacampus Investment
Reduce Capital Spend
and Funding Needs
Consider Flexible and
Opportunistic Share
Buyback Plan
Substantially Complete
Large-Scale Non-Core
Disposition Plan
Steadily Improve Occupancy
and Increase NOI, Focusing on
Leasing to All Sectors of Our
Tenant Base, Including the Most
Innovative Entities in a Rapidly
Changing Environment
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(1)Source: U.S. House Committee on Energy and Commerce, “The 21st Century Cures Discussion Document White Paper,” January 27, 2015. 
(2)Source: PhRMA, “Medicines in Development for Chronic Diseases: 2024 Report.”
(3)Source: Centers for Disease Control and Prevention, “Heart Disease Facts,” October 24, 2024. Represents the latest published data, which reflects the U.S. estimate for 2022.
(4)Source: National Cancer Institute, “Cancer Statistics,” updated May 7, 2025. Represents the latest published data, which reflects 2018–2021 data, not including 2020 due to lack of collection during COVID-19 pandemic.
(5)Source: Alzheimer’s Association, “2025 Alzheimer’s Disease Facts and Figures.” Represents the latest published data, which reflects the U.S. estimate for 2025.
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ALEXANDRIA: THE MOST
TRUSTED BRAND IN LIFE
SCIENCE REAL ESTATE
WE INVENTED IT.
WE DOMINATE IT.
ALEXANDRIA’S
MEGACAMPUS
PLATFORM REPRESENTS
78%
OF OUR ANNUAL
RENTAL REVENUE
LARGEST, HIGHEST-QUALITY
ASSET BASE CLUSTERED IN
THE KEY CENTERS OF LIFE
SCIENCE INNOVATION
SECTOR-LEADING CLIENT
TENANT BASE
HIGH-QUALITY CASH FLOWS
PROVEN UNDERWRITING
FORTRESS BALANCE SHEET
LONG-TENURED, HIGHLY
EXPERIENCED MANAGEMENT TEAM
As of December 31, 2025. Refer to “Definitions and reconciliations” in the Supplemental Information for additional details.
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Alexandria Executes Lease Through 2041 With High-Credit Tenant
AstraZeneca for 171,239 RSF Mission-Critical Manufacturing Facility
in Maryland
This long-term lease at 700 Quince Orchard Road demonstrates AstraZeneca’s commitment to Maryland
and brings its aggregate footprint across multiple Alexandria cluster markets to over 600,000 RSF
ONSHORING PHARMA SUPPLY CHAINS &
ACCELERATING ACCESS TO TRANSFORMATIVE THERAPIES
AstraZeneca’s new Gaithersburg facility aims to
accelerate the production of innovative
medicines for cancer, rare, and chronic
diseases
The investment builds upon AstraZeneca’s
$300M investment in a cell therapy
manufacturing facility at 9950 Medical Center
Drive on the Alexandria Center® for Life
Science – Shady Grove Megacampus™
AstraZeneca’s announced $2B(1) investment in
Maryland includes substantial support for
mission-critical manufacturing at 700 Quince
Orchard Road
AstraZeneca has committed to invest $50B(2) in
U.S.-based manufacturing and R&D by 2030
(1)Source: AstraZeneca, “ AstraZeneca plans $2 billion manufacturing investment in Maryland, supporting 2,600 jobs and catalyzing economic growth,” November 21, 2025.
(2)Source: AstraZeneca, “ AstraZeneca plans to invest $50 billion in America for medicines manufacturing and R&D,” July 21, 2025.
2025 Dispositions and Sales of Partial Interests Update
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35
COMPLETED
TRANSACTIONS(1)
$1.8B
TOTAL SALES(1)
$642M
TOTAL GAIN ON
SALES OF REAL ESTATE(1)
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Stabilized
Properties
Land
Non-Stabilized Properties
2025 DISPOSITIONS AND SALES OF PARTIAL INTERESTS
BY REAL ESTATE CLASSIFICATION
(1)Refer to “2025 dispositions and sales of partial interests” in the Earnings Press Release for additional details.
Alexandria’s Long-Standing Track Record of Monetizing Embedded
Asset Value: 2019–2025 Dispositions and Partial Interest Sales
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20192025
AGGREGATE
$11B
Total Sales(1)
$3.9B
Total Gains on
Sales of Real Estate(2)
$2.8B
Total Impairments
of Real Estate(2)
20192025 DISPOSITIONS AND PARTIAL INTEREST SALES
(2)
(1)
(2)
(1)Represents aggregate sales from outright sales and sales of partial interests.
(2)Total gains and impairments represent our share and include any amounts related to sales of partial interests recognized in additional paid-in capital.
Alexandria’s Key Disposition In 4Q25 — 409 and 499 Illinois Street in Mission Bay
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Alexandria’s opportunistic sale to UCSF,
a longstanding tenant, generates
proceeds to recycle into the business
and enables UCSF to expand its
Mission Bay campus.
$767.1M
$180.3M
(Our Share)(1)
SALES PRICE IN 4Q25
$1,645
SALES PRICE PER RSF
$416.7M
$103.9M
(Our Share)
GAIN ON SALE OF
REAL ESTATE
$293.0M
ARE ORIGINAL PURCHASE
PRICE (2011)
40%
OCCUPANCY AS OF 3Q25
(1)Represents our share of the sales price, net of seller credits and sales costs.
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ALEXANDRIA CONTINUES TO HAVE A STRONG AND FLEXIBLE
BALANCE SHEET WITH SIGNIFICANT LIQUIDITY
SIGNIFICANT
LIQUIDITY
PERCENTAGE OF FIXED-RATE
DEBT SINCE 2021(1)
$5.3B
96.7%
REMAINING DEBT TERM
(IN YEARS)
DEBT INTEREST
RATE
12.1
3.91%
Longest Among S&P 500 REITs(3)
ACHIEVED
4Q25 LEVERAGE(2)
5.7x
WEIGHTED AVERAGE
TOP 15%
BBB+
Negative
Baa1
Negative
CREDIT RATING RANKING AMONG
ALL PUBLICLY TRADED U.S. REITS(4)
As of December 31, 2025. Refer to “Definitions and reconciliations” in the Supplemental Information for additional details.
(1)Represents the average quarterly percentage fixed-rate debt as of each quarter-end from January 1, 2021 through December 31, 2025.
(2)Represents net debt and preferred stock to Adjusted EBITDA for the fourth quarter annualized.
(3)Sources: S&P Global Market Intelligence, Bloomberg, or company filings (data not disclosed for SBAC, PSA, and WY) as of September 30, 2025, except for ARE, which is as of December 31, 2025.
(4)Top 15% ranking represents credit rating levels from S&P Global Ratings and Moody’s Ratings for publicly traded U.S. REITs, from Bloomberg Professional Services and Nareit, as of December 31, 2025.
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12%
17%
(2)
As of December 31, 2025. Refer to “Definitions and reconciliations” in the Supplemental Information for additional details.
(1)Represents non-core assets outside our Megacampus ecosystems.
(2)Excludes properties classified as held for sale, of which land parcels represent approximately 1% of total non-income producing assets.
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CONTINUE TO SUCCESSFULLY MANAGE AND REDUCE G&A
Alexandria’s General and Administrative Expense Levels Outperform Other S&P 500 REITs
$76M
Projected Cumulative
G&A Savings
in 2025 and 2026
Compared to 2024(1)
5.6%
11.3%
Alexandria
4Q25(2)
S&P 500 REIT
Average 2023–3Q25
(Excluding Alexandria)(3)
GENERAL AND ADMINISTRATIVE EXPENSES AS A
PERCENTAGE OF NET OPERATING INCOME(4)
(1)Based on the midpoint of our guidance range for 2026 general and administrative expenses disclosed on January 26, 2026.
(2)Trailing twelve months ended December 31, 2025.
(3)Source for S&P 500 REIT data: S&P Global Market Intelligence. Represents the annual average of the years ended December 31, 2024 and 2023 and the trailing twelve months ended September 30, 2025.
(4)Refer to “Net operating income” under “Definitions and reconciliations” in the Supplemental Information for additional details.
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Alexandria Real Estate Equities, Inc. Reports
4Q25 and 2025 Net Loss per Share – Diluted of $6.35 and $8.44, respectively; and
4Q25 and 2025 FFO per Share – Diluted, as Adjusted, of $2.16 and $9.01, respectively
PASADENA, Calif. – January 26, 2026 – Alexandria Real Estate Equities, Inc. (NYSE: ARE)
announced financial and operating results for the fourth quarter and year ended December 31,
2025.
Key highlights
YTD
Operating results
4Q25
4Q24
2025
2024
Net (loss) income attributable to Alexandria’s common stockholders – diluted:
In millions
$(1,081.8)
$(64.9)
$(1,438.0)
$309.6
Per share
$(6.35)
$(0.38)
$(8.44)
$1.80
Funds from operations attributable to Alexandria’s common stockholders – diluted, as adjusted:
In millions
$368.5
$411.8
$1,534.7
$1,629.1
Per share
$2.16
$2.39
$9.01
$9.47
A best-in-class REIT with a high-quality, diverse tenant base, strong margins, and long lease
terms
(As of December 31, 2025, unless stated otherwise)
Occupancy of operating properties in North America
90.9%
Percentage of annual rental revenue in effect from Megacampus™ platform
78%
Percentage of annual rental revenue in effect from investment-grade or publicly
traded large cap tenants
53%
Operating margin
69%
Adjusted EBITDA margin
70%
Percentage of leases containing annual rent escalations
97%
Weighted-average remaining lease term:
Top 20 tenants
9.7
years
All tenants
7.5
years
Strong 4Q25 tenant collections:
4Q25 tenant rents and receivables collected as of January 26, 2026
99.9%
Strong and flexible balance sheet with significant liquidity; top 15% credit rating ranking among all
publicly traded U.S. REITs
$20.75 billion in total market capitalization.
$8.35 billion in total equity capitalization.
Net debt and preferred stock to Adjusted EBITDA of 5.7x and fixed-charge coverage ratio of
3.7x for 4Q25 annualized.
As of December 31, 2025
Significant liquidity of $5.30 billion, or 3.7x of our debt maturities through 2028.
Only 11% of our total debt matures through 2028.
12.1 years weighted-average remaining term of debt, longest among S&P 500 REITs.
Our fixed-rate debt represents 97.2% of our total debt, which provides predictability in debt
servicing costs. Since 2021, our quarter-end fixed-rate debt has averaged 96.7%.
Total debt and preferred stock to gross assets of 31%.
Solid leasing volume
Leasing volume of 1.2 million RSF during 4Q25.
Leasing of previously vacant space aggregating 393,376 RSF, up 98%, over the quarterly
average over the last five quarters.
Rental rates on renewals and re-leasing of space decreased by 9.9% and 5.2% (cash basis)
for 4Q25 and increased by 7.0% and 3.5% (cash basis) for 2025.
82% of our leasing activity during the last twelve months was generated from our existing
tenant base.
4Q25
2025
Lease renewals and re-leasing of space:
Rental rate changes
(9.9)%
7.0%
Rental rate changes (cash basis)
(5.2)%
3.5%
RSF
821,289
2,543,473
Leasing of previously vacant space – RSF
393,376
944,362
Leasing of development and redevelopment space – RSF
6,279
704,821
Total leasing activity – RSF
1,220,944
4,192,656
Dividend strategy to share net cash flows from operating activities with stockholders while
retaining a significant portion for reinvestment
Common stock dividend declared of $0.72 per share for 4Q25, representing a 45% reduction
from the quarterly dividend declared of $1.32 for 3Q25.
The decision to reduce the declared dividend per common share reflects our commitment to
maintaining the strength of our balance sheet, enhancing financial flexibility, and preserving
liquidity of approximately $410 million on an annual basis, which will be used to support our
2026 capital plan.
Significant net cash flows provided by operating activities after dividends retained for
reinvestment aggregating $2.36 billion for the years ended December 31, 2021 through 2025.
Dividend yield of 5.9% as of December 31, 2025 and dividend payout ratio of 33% for the
three months ended December 31, 2025.
Successful execution of Alexandria’s capital recycling strategy
We exceeded the midpoint of our 2025 guidance for dispositions and sales of partial interests
by completing $1.81 billion of funding, primarily from sales of non-core assets and land, as well
as sales to owner/users. During 4Q25, we completed $1.47 billion of dispositions.
(dollars in millions)
Sales Price
YTD 3Q25
$341
4Q25
1,471
Total 2025 dispositions and sales of partial interests(1)
$1,812
Types of dispositions in 2025(1)
% of Sales Price
Land
21%
Non-stabilized properties
59
Stabilized properties
20
Total 2025 dispositions
100%
(1)Excludes the exchange of partial interests in two consolidated real estate joint ventures, Pacific Technology
Park and 199 East Blaine Street, during the three months ended September 30, 2025. Refer to ”2025
dispositions and sales of partial interests” in this Earnings Press Release for additional details.
As of December 31, 2025, the book value of our real estate assets designated as held for
sale aggregated $581.7 million. We expect to sell these assets in 2026.
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Fourth Quarter and Year Ended December 31, 2025 Financial and Operating Results (continued)
December 31, 2025
Increased occupancy and leasing progress on temporary vacancy
Operating occupancy as of September 30, 2025
90.6%
Assets with vacancy designated as held for sale or sold during 4Q25
0.5
Early termination of one lease aggregating 170,618 RSF at 259 East Grand
Avenue in South San Francisco, originally set to expire in early 2027, which is
already fully re-leased to a new tenant with occupancy expected to commence in
2H26
(0.5)
(1)
Reclassification of 401 Park Avenue from redevelopment to operating upon our
decision to pursue leasing as office space rather than convert to laboratory space
(0.3)
Other changes in occupancy, primarily due to the commencement of leases during
4Q25
0.6
Operating occupancy as of December 31, 2025
90.9
Key vacant space leased with future delivery
2.5
(2)
Operating occupancy as of December 31, 2025, including leased but not yet
delivered space
93.4%
(1)Refer to “Guidance” in the Earnings Press Release for key considerations on 1Q26 guidance.
(2)Represents temporary vacancies as of December 31, 2025 aggregating 899,259 RSF, primarily in the Greater
Boston, San Francisco Bay Area, and Seattle markets, that are leased and expected to be occupied upon
completion of building and/or tenant improvements. The weighted-average expected delivery date is
approximately August 2026 and the expected annual rental revenue is approximately $52 million.
Key operating metrics
Operating metrics
4Q25
2025
(dollars in millions)
Net operating income (cash basis)
$1,985
(1)
$1,978
(Decrease) Increase compared to 4Q24 and 2024
(3.4)%
(2)
0.1%
(2)
Same property performance:
Net operating income changes
(6.0)%
(3.5)%
Net operating income changes (cash basis)
(1.7)%
0.9%
Occupancy – current-period average
91.0%
92.5%
Occupancy – same-period prior-year average
95.5%
95.2%
(1)Quarter annualized.
(2)Change in net operating income (cash basis) includes the impact of operating properties disposed of after
January 1, 2024. Excluding these dispositions, net operating income (cash basis) annualized for the three
months ended December 31, 2025 and for the year ended December 31, 2025 would have increased by 1.4%
and 6.2%, respectively, compared to the corresponding periods in 2024.
Continued successful management and reduction of general and administrative expenses
General and administrative expenses as a percentage of net operating income for the year
ended December 31, 2025 were 5.6% — the lowest level in the past ten years for the
Company and approximately half the average of other S&P 500 REITs. In 2025, we realized
cost reductions of $51.3 million, or 30%, compared to 2024, primarily from cost-control and
efficiency initiatives. Some of these cost savings are temporary in nature, and we anticipate
that approximately half of the cost reduction achieved in 2025 will continue in 2026.
Compared to the general and administrative expenses for the year ended December 31,
2024, we expect to achieve a savings of $76 million of cumulative general and
administrative expense in 2025 and 2026 based upon the midpoint of our guidance range
for 2026 general and administrative expenses.
Reduction of capital spend and funding needs
During 4Q25, we reduced future construction funding requirements across our active pipeline
by: i) selling or designating as held for sale three projects and ii) pivoting one project to a
lower investment strategy; enabling us to redeploy future construction savings and sale
proceeds into opportunities aligned with our long‑term Megacampus strategy.
We reduced the overall size of our future construction funding needs on current
development and redevelopment projects by more than $300 million over the next few
years.
3% reduction in non-income-producing assets to 17% as a percentage of gross assets.
We are evaluating business strategy for four additional projects.
Alexandria’s development and redevelopment pipeline delivered incremental annual net operating
income of $10 million commencing during 4Q25, with an additional $97 million of incremental
annual net operating income anticipated to deliver by 4Q26 primarily from projects that are 86%
leased/negotiating
During 4Q25, we placed into service one development project aggregating 139,979 RSF that
is 100% occupied at 10075 Barnes Canyon Road in our Sorrento Mesa submarket and
delivered incremental annual net operating income of $10 million.
Annual net operating income (cash basis) from recently delivered projects is expected to
increase by $26 million upon the burn-off of initial free rent, which has a weighted-average
remaining period of approximately six months.
77% of the RSF in our total development and redevelopment pipeline is within our
Megacampus ecosystems.
Development and Redevelopment
Projects
Incremental
Annual Net
Operating Income
RSF
Leased/
Negotiating
Percentage
(dollars in millions)
Expected to be placed into service:
2026
$97
(1)
699,933
(2)
86%
(3)
2027- 2028
123
1,614,994
51%
$220
Projects under business strategy evaluation:
2026-2028
$113
1,248,227
8%
(1)Includes expected partial deliveries through 2026 from projects expected to stabilize in 2027-2028, including
speculative future leasing that is not yet fully committed. Refer to the initial and stabilized occupancy years
under “New Class A/A+ development and redevelopment properties: current projects” in the Supplemental
Information for additional details.
(2)Represents the RSF of projects expected to stabilize in 2026. Does not include RSF for partial deliveries
through 2026 from projects expected to stabilize in 2027-2028.
(3)Represents the current leased/negotiating percentage of development and redevelopment projects that are
expected to stabilize through 2026.
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Fourth Quarter and Year Ended December 31, 2025 Financial and Operating Results (continued)
December 31, 2025
Key capital events
On December 8, 2025, we announced that our board of directors authorized a common stock
repurchase program under which we may repurchase up to $500.0 million of our common
stock through December 31, 2026. The new program replaces the prior repurchase
authorization for up to $500.0 million that was set to expire on December 31, 2025. During
4Q25, no shares were repurchased. 
In January 2026, we repaid $300.0 million of 4.30% unsecured senior notes payable upon
maturity. No gain or loss was incurred in connection with this repayment.
Investments
As of December 31, 2025:
Our non-real estate investments aggregated $1.50 billion.
Unrealized gains presented in our consolidated balance sheet were $133.4 million,
comprising gross unrealized gains and losses aggregating $184.4 million and $51.1 million,
respectively.
Investment loss of $3.9 million for 4Q25 presented in our consolidated statement of
operations consisted of $21.1 million of realized gains, $103.3 million from a significant
realized loss on one transaction, $98.5 million of unrealized gains, and $20.2 million of
impairment charges.
Guidance
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December 31, 2025
(Dollars in millions, except per share amounts)
Based on our current view of existing market conditions and assumptions for the year ending December 31, 2026, our guidance for 2026 that was initially provided on December 3, 2025 has been
reiterated as of January 26, 2026. Actual results may be materially higher or lower than these expectations. Our guidance for 2026 is subject to a number of variables and uncertainties, including, but not limited to,
leasing velocity and overall tenant demand, actions and changes in policy by the current U.S. administration related to the regulatory environment, life science funding, the U.S. Food and Drug Administration and
National Institutes of Health, trade, and other areas. For additional discussion relating to risks and uncertainties that could cause actual results to differ materially from those anticipated, refer to our discussion of
“forward-looking statements” on page 7 of the Earnings Press Release as well as our SEC filings, including our most recent annual report on Form 10-K and any subsequent quarterly reports on Form 10-Q.
Projected 2026 Funds From Operations per Share Attributable to Alexandria’s Common
Stockholders – Diluted
Funds from operations per share, as adjusted(1)
$6.25 to $6.55
Midpoint
$6.40
Key Assumptions
Low
High
Occupancy percentage in North America as of December 31, 2026(2)
87.7%
89.3%
Lease renewals and re-leasing of space:
Rental rate changes
(2.0)%
6.0%
Rental rate changes (cash basis)
(12.0)%
(4.0)%
Same property performance:
Net operating income
(9.5)%
(7.5)%
Net operating income (cash basis)
(9.5)%
(7.5)%
Straight-line rent revenue
$65
$95
General and administrative expenses
$134
$154
Capitalization of interest(3)
$225
$275
Interest expense
$230
$280
Realized gains on non-real estate investments(4)
$60
$90
Key Credit Metric Targets
Net debt and preferred stock to Adjusted EBITDA – 4Q26 annualized
5.6x to 6.2x
Fixed-charge coverage ratio – 4Q26 annualized
3.6x to 4.1x
Key Sources and Uses of Capital
Range
Midpoint
Sources of capital:
Reduction in debt(5)
$(1,075)
$(2,275)
$(1,675)
Net cash provided by operating activities after dividends
475
575
525
Dispositions and sales of partial interests (refer to page 6)(6)
2,100
3,700
2,900
Total sources of capital
$1,500
$2,000
$1,750
Uses of capital:
Construction
$1,500
$2,000
$1,750
Total uses of capital
$1,500
$2,000
$1,750
Reduction in debt (included above):
Repayment of unsecured notes payable with 2026 maturities(7)
$(650)
$(650)
$(650)
Unsecured senior line of credit, commercial paper, and other
(425)
(1,625)
(1,025)
Reduction in debt
$(1,075)
$(2,275)
$(1,675)
Refer to “Definitions and reconciliations” in the Supplemental Information for additional details on key credit metrics.
(1)Refer to “Funds from operations and funds from operations, as adjusted, attributable to Alexandria’s common stockholders” under “Definitions and reconciliations” in the Supplemental Information for additional details.
(2)Our guidance for operating occupancy percentage in North America as of December 31, 2026 assumes an approximate 2% benefit related to a range of assets with vacancy that could potentially be sold during 2026 and/or qualify for
designation as held for sale by December 31, 2026 but that have not yet qualified for such designation as of December 31, 2025.
(3)Refer to “Capitalization of interest” in the Supplemental Information for additional details.
(4)Represents realized gains and losses included in funds from operations per share – diluted, as adjusted. Excludes unrealized gains and losses and significant impairments realized on non-real estate investments, if any. Refer to
“Investments” in the Supplemental Information for additional details.
(5)Our debt repayment goals include repaying existing short-term borrowings, including amounts outstanding on our commercial paper program, repaying our 2026 unsecured senior note payable maturities aggregating $650 million, and
potentially repaying other unsecured senior notes payable, including our 2027 maturity.
(6)We expect to achieve a weighted-average capitalization rate on our projected 2026 non-core operating dispositions (includes stabilized and non-stabilized properties and excludes land) in the 8.5%–9.5% range. We expect dispositions of
land to represent 25%–35% of our total dispositions and sales of partial interests for the year ending December 31, 2026. We expect the remaining balance to include approximately 25%–35% core assets and 35%–45% non-core assets.
As of January 26, 2026, our share of pending transactions subject to non-refundable deposits, signed letters of intent, or purchase and sale agreement negotiations aggregated $180.7 million.
(7)In January 2026, we repaid $300.0 million of 4.30% unsecured senior notes payable upon maturity, funded temporarily with borrowings under our commercial paper program. We expect to repay these temporary borrowings with proceeds
from future dispositions and sales of partial interests. No gain or loss was incurred in connection with this repayment.
Guidance (continued)
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December 31, 2025
Key considerations for funds from operations and adjusted EBITDA for 1Q26
The following key considerations are expected to impact our quarterly funds from operations per share results in 1Q26. These items will also affect our Adjusted EBITDA beginning in
1Q26. As a result, we expect our net debt and preferred stock to Adjusted EBITDA ratio to temporarily increase in 1Q26 (on a quarter annualized basis) by approximately 1.0x to 1.5x higher
than our 4Q25 annualized ratio of 5.7x. We expect this ratio to trend downward through the remainder of 2026 as we make progress on our disposition and sales of partial interests program,
with a target net debt and preferred stock to Adjusted EBITDA ratio of 5.6x to 6.2x for 4Q26 annualized, which is unchanged from our initial 2026 guidance provided on December 3, 2025.
4Q25 Dispositions
We completed $1.47 billion of dispositions during 4Q25. These dispositions had annual net operating income of $118 million (based on consolidated 3Q25 annualized results) with a
weighted-average disposition date of December 9, 2025.  Refer to “2025 Dispositions and sales of partial interests” in the Earnings Press Release for additional details.
2026 key lease expirations with expected downtime
There are key lease expirations primarily in our Greater Boston, San Francisco Bay Area, and San Diego markets, aggregating 1.2 million RSF, with a weighted‑average lease
expiration date in April 2026 and annual rental revenue of $71 million. These leases are expected to become vacant upon expiration, and we anticipate downtime on these spaces to
range from 6 to 24 months on a weighted‑average basis. 150,822 RSF has been leased or is under negotiations and we have identified prospective tenants or have early negotiations
for another 468,470 RSF. We expect a decline in net operating income of approximately $14 million for the three months ending March 31, 2026, compared to the three months ended
December 31, 2025, related to the portion of these leases that are scheduled to expire in 1Q26, which includes operating expenses that will not be recoverable once the spaces
become vacant. Refer to “Contractual lease expirations” in the Supplemental Information for additional details.
Certain items included in 4Q25 results not expected to reoccur in 1Q26
During 4Q25, we terminated a lease at one property in our South San Francisco submarket aggregating 170,618 RSF, which had generated annual rental revenue of $11.4 million,
ahead of its contractual lease expiration in early 2027. The termination allowed us to re-lease 100% of the space to a new tenant, with occupancy expected to commence in 2H26
following the completion of tenant improvements. As a result of the termination, we recognized incremental rental revenue of $8.4 million during 4Q25, primarily from a termination
fee, net of the deferred rent balances written off.
We recognized an asset management fee paid by our joint venture partner aggregating $7.0 million in connection with the disposition of 409 and 499 Illinois Street in 4Q25, which is
included in other income. Other income in 4Q25 was $25.5 million, or 3.4% of total revenues, compared to an average of $19.5 million, or 2.5% of total revenues, for the preceding
five quarters.
Potential tenant wind-downs
Our 2026 guidance assumes reduction of rent in 2026 aggregating $20–$25 million (or approximately $6 million per quarter at the midpoint of the range) related to potential tenant
wind-downs and downtime without immediate backfill.
General and administrative expenses
General and administrative expenses for the year ended December 31, 2025 was $117.0 million and $28.0 million for the fourth quarter of 2025. Our guidance range for 2026 general
and administrative expenses is $134 million to $154 million, with a midpoint of $144 million, or a quarterly average of approximately $36 million. Despite the anticipated increase in
general and administrative expenses in 2026 compared to 2025, the midpoint of our guidance range for 2026 of $144 million, represents a 14% reduction compared to 2024, and
cumulative anticipated savings aggregating $76 million for 2025 and 2026.
Realized gains on non-real estate investments
Realized gains included in funds from operations per share – diluted, as adjusted, for the year ended December 31, 2025 were $115.7 million and $21.1 million for the fourth quarter
of 2025. Our guidance range for 2026 realized gains on non-real estate investments is $60 million to $90 million, with a midpoint of $75 million (or a quarterly average of
approximately $18.8 million). Refer to “Investments” in the Supplemental Information for additional details.
2025 Dispositions and Sales of Partial Interests
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December 31, 2025
(Dollars in thousands)
Interest
Sold
Square Footage
Capitalization
Rate
Capitalization
Rate
(Cash Basis)
Price
(Our Share)
Gain on
Sales of
Real Estate
Property
Submarket/Market
Date of
Transaction
Operating
Future
Development
Completed in YTD 3Q25, excluding exchange of partial interests (see below)
$340,871
$13,241
(1)
Completed in 4Q25:
Stabilized properties:
550 Arsenal Street(2)
Cambridge/Inner Suburbs/Greater Boston
10/15/25
100%
249,275
281,592
6.1%
5.4%
99,250
6260 Sequence Drive
Sorrento Mesa/San Diego
12/16/25
100%
130,536
7.2%
7.1%
70,000
5600 Avenida Encinas
Other/San Diego
12/17/25
100%
182,276
5.5%
5.3%
64,100
601 Keystone Park Drive
Research Triangle/Research Triangle
10/3/25
100%
77,595
9.7%
8.7%
24,879
4,362
Other stabilized properties
Various
307,142
103,079
361,308
Properties with vacancy or significant near-term capital requirements:
601, 611, 651, 681, 685, 701, and 751
Gateway Boulevard
South San Francisco/San Francisco Bay
Area
12/30/25
(3)
1,104,826
528,684
N/A
283,173
(3)
(3)
ARE Nautilus
Torrey Pines/San Diego
12/10/25
100%
218,640
192,000
(4)
86,260
409 and 499 Illinois Street
Mission Bay/San Francisco Bay Area
12/17/25
25%
466,297
180,273
(5)
416,749
(5)
14 TW Alexander Drive
Research Triangle/Research Triangle
11/20/25
100%
173,820
155,000
(6)
78,489
4767 Nexus Center Drive
University Town Center/San Diego
12/31/25
100%
65,280
50,000
(7)
15,330
Alexandria Center for Life Science – Long
Island City
New York City/New York City
12/19/25
100%
179,100
34,500
Other non-stabilized properties
Various
469,992
117,227
97,183
746
992,129
Land:
9363, 9373, and 9393 Towne Centre Drive
University Town Center/San Diego
12/18/25
100%
230,000
N/A
40,000
17,978
285, 299, 307, and 345 Dorchester Avenue
Seaport Innovation District/Greater Boston
12/30/25
60%
1,040,000
33,500
3029 East Cornwallis Road
Research Triangle/Research Triangle
12/31/25
100%
600,000
29,500
Other land parcels
Various
211,232
14,900
117,900
Total dispositions completed in 4Q25
1,471,337
(8)
619,914
Total completed 2025 dispositions and sales of partial interests, excluding exchange of partial interests (see below)
$1,812,208
$633,155
Exchange of partial interests
Disposition of Pacific Technology Park
Sorrento Mesa/San Diego
9/9/25
50%
544,352
N/A
$96,000
$9,290
Acquisition of 199 East Blaine Street
Lake Union/Seattle
9/9/25
70%
115,084
(94,430)
Difference in sales price received in cash
$1,570
(1)Excludes a gain on sale of interest related to an unconsolidated real estate joint venture of $458 thousand, which is classified as equity in earnings of unconsolidated real estate joint ventures in our consolidated statement of operations.
(2)Represents a retail shopping center with future development opportunity. We originally acquired the property in 2021 with the intent to demolish the retail center and develop it into laboratory space. However, due to the project’s financial
outlook and the substantial capital that development would have required, we decided to recycle the capital generated by the disposition into our development and redevelopment pipeline.
(3)We held a 50% ownership interest at 601, 611, 651, 681, 685, and 701 Gateway Boulevard and a 51% interest at 751 Gateway Boulevard. At the time of sale, these properties had operating and redevelopment properties occupancy of
62%, with a weighted-average lease term of 5.1 years. Due to macroeconomic conditions in South San Francisco, including significant new supply, lower life science tenant demand, and ongoing challenges leasing both laboratory and
office space, we reassessed the project’s financial outlook and the substantial capital required to lease vacant space and to complete the redevelopment of 651 Gateway Boulevard and future development opportunities. As a result, we sold
the consolidated joint ventures for a gross price of $600.0 million ($560.4 million net of seller credits and sales costs), of which our share of the price (after seller credits) was $283.2 million.
(4)Represents the sale of a non-stabilized campus located outside of a Megacampus ecosystem. At the time of sale, the campus was 76% occupied, with a weighted-average remaining lease term of less than four years. Given our strategy to
invest into our Megacampus and the significant near‑term capital required to re‑stabilize the asset, we decided to reinvest the disposition proceeds into other projects with greater value-creation opportunities.
(5)Represents two life science buildings in which we held a 25% ownership interest. At the time of sale, the properties were 40% occupied, with a weighted-average remaining lease term of 8.3 years. These properties were sold by the joint
venture to an existing tenant following its exercise of a purchase right included in its lease agreement. The gross sales price was $767.1 million ($721.1 million net of seller credits and sales costs), of which our share of the price (after seller
credits) was $180.3 million. Our share of gain on sales of real estate was $103.9 million.
(6)Represents a non-stabilized property that was sold to a user. 
(7)We provided seller financing of $33.0 million.
(8)Our share of dispositions completed during the three months ended December 31, 2025 had annual net operating income of $93 million (based on 3Q25 annualized results) with a weighted-average disposition date of December 9, 2025.
Total consolidated annual net operating income related to these dispositions, including our partners’ share, is $118 million (based on 3Q25 annualized results).
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Earnings Call Information and About the Company
December 31, 2025
We will host a conference call on Tuesday, January 27, 2026, at 2:00 p.m. Eastern Time (“ET”)/11:00 a.m. Pacific Time (“PT”), which is open to the general public, to discuss our financial and operating
results for the fourth quarter and year ended December 31, 2025. To participate in this conference call, dial (833) 366-1125 or (412) 902-6738 shortly before 2:00 p.m. ET/11:00 a.m. PT and ask the operator to join
the call for Alexandria Real Estate Equities, Inc. The audio webcast can be accessed at www.are.com in the “For Investors” section. A replay of the call will be available for a limited time from 4:00 p.m. ET/1:00 p.m.
PT on Tuesday, January 27, 2026. The replay number is (855) 669-9658 or (412) 317-0088, and the access code is 4730896.
Additionally, a copy of this Earnings Press Release and Supplemental Information for the fourth quarter and year ended December 31, 2025 is available in the “For Investors” section of our website at
www.are.com or by following this link: https://www.are.com/fs/2025q4.pdf.
For any questions, please contact corporateinformation@are.com; Joel S. Marcus, executive chairman and founder; Peter M. Moglia, chief executive officer and chief investment officer; Marc E. Binda,
chief financial officer and treasurer; or Paula Schwartz, managing director of Rx Communications Group, at (917) 633-7790.
About the Company
Alexandria Real Estate Equities, Inc. (NYSE: ARE), an S&P 500® company, is a best-in-class, mission-driven life science REIT making a positive and lasting impact on the world. With our founding in 1994,
Alexandria pioneered the life science real estate niche. Alexandria is the preeminent and longest-tenured owner, operator, and developer of collaborative Megacampus™ ecosystems in AAA life science innovation
cluster locations, including Greater Boston, the San Francisco Bay Area, San Diego, Seattle, Maryland, Research Triangle, and New York City. As of December 31, 2025, Alexandria has a total market capitalization
of $20.75 billion and an asset base in North America that includes 35.9 million RSF of operating properties and 3.5 million RSF of Class A/A+ properties undergoing construction. Alexandria has a long-standing and
proven track record of developing Class A/A+ properties clustered in highly dynamic and collaborative Megacampus environments that enhance our tenants’ ability to successfully recruit and retain world-class talent
and inspire productivity, efficiency, creativity, and success. Alexandria also provides strategic capital to transformative life science companies through our venture capital platform. We believe our unique business
model and diligent underwriting ensure a high-quality and diverse tenant base that results in higher occupancy levels, longer lease terms, higher rental income, higher returns, and greater long-term asset value. For
more information on Alexandria, please visit www.are.com.
Forward-Looking Statements
This document includes “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended.
Such forward-looking statements include, without limitation, statements regarding our projected 2026 earnings per share, projected 2026 funds from operations per share, projected 2026 funds from operations per
share, as adjusted, projected net operating income, and our projected sources and uses of capital. You can identify the forward-looking statements by their use of forward-looking words, such as “forecast,”
“guidance,” “goals,” “projects,” “estimates,” “anticipates,” “believes,” “expects,” “intends,” “may,” “plans,” “seeks,” “should,” “targets,” or “will,” or the negative of those words or similar words. These forward-looking
statements are based on our current expectations, beliefs, projections, future plans and strategies, anticipated events or trends, and similar expressions concerning matters that are not historical facts, as well as a
number of assumptions concerning future events. There can be no assurance that actual results will not be materially higher or lower than these expectations. These statements are subject to risks, uncertainties,
assumptions, and other important factors that could cause actual results to differ materially from the results discussed in the forward-looking statements. Factors that might cause such a difference include, without
limitation, our failure to obtain capital (debt, construction financing, and/or equity) or refinance debt maturities, lower than expected yields, increased interest rates and operating costs, adverse economic or real
estate developments in our markets, our failure to successfully place into service and lease any properties undergoing development or redevelopment and our existing space held for future development or
redevelopment (including new properties acquired for that purpose), our failure to successfully operate or lease acquired properties, decreased rental rates, increased vacancy rates or failure to renew or replace
expiring leases, defaults on or non-renewal of leases by tenants, adverse general and local economic conditions, an unfavorable capital market environment, decreased leasing activity or lease renewals, failure to
obtain LEED and other healthy building certifications and efficiencies, and other risks and uncertainties detailed in our filings with the Securities and Exchange Commission (“SEC”). Accordingly, you are cautioned
not to place undue reliance on such forward-looking statements. All forward-looking statements are made as of the date of this Earnings Press Release and Supplemental Information, and unless otherwise stated,
we assume no obligation to update this information and expressly disclaim any obligation to update or revise any forward-looking statements, whether as a result of new information, future events, or otherwise. For
more discussion relating to risks and uncertainties that could cause actual results to differ materially from those anticipated in our forward-looking statements, and risks to our business in general, please refer to our
SEC filings, including our most recent annual report on Form 10-K and any subsequent quarterly reports on Form 10-Q.
This document is not an offer to sell or a solicitation to buy securities of Alexandria Real Estate Equities, Inc. Any offers to sell or solicitations to buy our securities shall be made only by means of a
prospectus approved for that purpose. Unless otherwise indicated, the “Company,” “Alexandria,” “ARE,” “we,” “us,” and “our” refer to Alexandria Real Estate Equities, Inc. and our consolidated subsidiaries.
Alexandria®, Lighthouse Design® logo, Building the Future of Life-Changing Innovation®, That’s What’s in Our DNA®, Megacampus™, At the Vanguard and Heart of the Life Science Ecosystem™, Alexandria
Center®, Alexandria Technology Square®, Alexandria Technology Center®, and Alexandria Innovation Center® are copyrights and trademarks of Alexandria Real Estate Equities, Inc. All other company names,
trademarks, and logos referenced herein are the property of their respective owners.
Consolidated Statements of Operations
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December 31, 2025
(Dollars in thousands, except per share amounts)
 
Three Months Ended
Year Ended
 
12/31/25
9/30/25
6/30/25
3/31/25
12/31/24
12/31/25
12/31/24
Revenues:
 
 
 
 
 
 
 
Income from rentals
$728,872
$735,849
$737,279
$743,175
$763,249
$2,945,175
$3,049,706
Other income
25,542
(1)
16,095
24,761
14,983
25,696
81,381
66,688
Total revenues
754,414
751,944
762,040
758,158
788,945
3,026,556
3,116,394
Expenses:
Rental operations
232,543
239,234
224,433
226,395
240,432
922,605
909,265
General and administrative
28,020
29,224
29,128
30,675
32,730
117,047
168,359
Interest
65,674
54,852
55,296
50,876
55,659
226,698
185,838
Depreciation and amortization
322,063
340,230
346,123
342,062
330,108
1,350,478
1,202,380
Impairment of real estate
1,717,188
(2)
323,870
129,606
32,154
186,564
2,202,818
223,068
Loss on early extinguishment of debt
107
107
Total expenses
2,365,488
987,517
784,586
682,162
845,493
4,819,753
2,688,910
Equity in (losses) earnings of unconsolidated real estate joint ventures
(304)
201
(9,021)
(507)
6,635
(9,631)
7,059
Investment (loss) income
(3,890)
28,161
(30,622)
(49,992)
(67,988)
(56,343)
(53,122)
Gain on sales of real estate
619,914
(2)
9,366
13,165
101,806
642,445
129,312
Net (loss) income
(995,354)
(197,845)
(62,189)
38,662
(16,095)
(1,216,726)
510,733
Net income attributable to noncontrolling interests
(85,521)
(2)
(34,909)
(44,813)
(47,601)
(46,150)
(212,844)
(187,784)
Net (loss) income attributable to Alexandria Real Estate Equities, Inc.’s
stockholders
(1,080,875)
(232,754)
(107,002)
(8,939)
(62,245)
(1,429,570)
322,949
Net income attributable to unvested restricted stock awards
(965)
(2,183)
(2,609)
(2,660)
(2,677)
(8,417)
(13,394)
Net (loss) income attributable to Alexandria Real Estate Equities, Inc.’s
common stockholders
$(1,081,840)
$(234,937)
$(109,611)
$(11,599)
$(64,922)
$(1,437,987)
$309,555
Net (loss) income per share attributable to Alexandria Real Estate Equities,
Inc.’s common stockholders:
Basic
$(6.35)
$(1.38)
$(0.64)
$(0.07)
$(0.38)
$(8.44)
$1.80
Diluted
$(6.35)
$(1.38)
$(0.64)
$(0.07)
$(0.38)
$(8.44)
$1.80
Weighted-average shares of common stock outstanding:
Basic
170,394
170,181
170,135
170,522
172,262
170,307
172,071
Diluted
170,394
170,181
170,135
170,522
172,262
170,307
172,071
Dividends declared per share of common stock
$0.72
$1.32
$1.32
$1.32
$1.32
$4.68
$5.19
(1)Includes an asset management fee paid by our joint venture partner of $7.0 million, which was recognized in connection with the disposition of 409 and 499 Illinois Street. Refer to “2025 dispositions and sales of partial interests” in the
Earnings Press Release for additional details.
(2)Refer to footnote 1 and 2 in “Funds from operations and funds from operations per share” in the Earnings Press Release for additional details.
Consolidated Balance Sheets
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December 31, 2025
(In thousands)
12/31/25
9/30/25
6/30/25
3/31/25
12/31/24
Assets
 
 
 
 
Investments in real estate
$28,689,996
$31,743,917
$32,160,600
$32,121,712
$32,110,039
Investments in unconsolidated real estate joint ventures
30,677
39,601
40,234
50,086
39,873
Cash and cash equivalents
549,062
579,474
520,545
476,430
552,146
Restricted cash
4,693
4,705
7,403
7,324
7,701
Tenant receivables
6,672
6,409
6,267
6,875
6,409
Deferred rent
1,179,403
1,257,378
1,232,719
1,210,584
1,187,031
Deferred leasing costs
458,311
505,241
491,074
489,287
485,959
Investments
1,501,249
1,537,638
1,476,696
1,479,688
1,476,985
Other assets
1,661,772
1,700,785
1,688,091
1,758,442
1,661,306
Total assets
$34,081,835
$37,375,148
$37,623,629
$37,600,428
$37,527,449
Liabilities, Noncontrolling Interests, and Equity
Secured notes payable
$
$
$153,500
$150,807
$149,909
Unsecured senior notes payable
12,047,394
12,044,999
12,042,607
12,640,144
12,094,465
Unsecured senior line of credit and commercial paper
353,161
1,548,542
1,097,993
299,883
Accounts payable, accrued expenses, and other liabilities
2,397,073
2,432,726
2,360,840
2,281,414
2,654,351
Dividends payable
127,771
230,603
229,686
228,622
230,263
Total liabilities
14,925,399
16,256,870
15,884,626
15,600,870
15,128,988
Commitments and contingencies
Redeemable noncontrolling interests
58,788
58,662
9,612
9,612
19,972
Alexandria Real Estate Equities, Inc.’s stockholders’ equity:
Common stock
1,705
1,703
1,701
1,701
1,722
Additional paid-in capital
15,497,760
16,669,802
17,200,949
17,509,148
17,933,572
Accumulated other comprehensive loss
(29,395)
(32,203)
(27,415)
(46,202)
(46,252)
Alexandria Real Estate Equities, Inc.’s stockholders’ equity
15,470,070
16,639,302
17,175,235
17,464,647
17,889,042
Noncontrolling interests
3,627,578
4,420,314
4,554,156
4,525,299
4,489,447
Total equity
19,097,648
21,059,616
21,729,391
21,989,946
22,378,489
Total liabilities, noncontrolling interests, and equity
$34,081,835
$37,375,148
$37,623,629
$37,600,428
$37,527,449
Funds From Operations and Funds From Operations per Share
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December 31, 2025
(In thousands)
The following table presents a reconciliation of net income (loss) attributable to Alexandria’s common stockholders, the most directly comparable financial measure presented in accordance
with U.S. generally accepted accounting principles (“GAAP”), including our share of amounts from consolidated and unconsolidated real estate joint ventures, to funds from operations attributable to
Alexandria’s common stockholders – diluted, and funds from operations attributable to Alexandria’s common stockholders – diluted, as adjusted, for the periods below:
 
Three Months Ended
Year Ended
12/31/25
9/30/25
6/30/25
3/31/25
12/31/24
12/31/25
12/31/24
Net (loss) income attributable to Alexandria’s common stockholders – basic and diluted
$(1,081,840)
$(234,937)
$(109,611)
$(11,599)
$(64,922)
$(1,437,987)
$309,555
Depreciation and amortization of real estate assets
319,865
338,182
343,729
339,381
327,198
1,341,157
1,191,524
Noncontrolling share of depreciation and amortization from consolidated real estate JVs
(39,942)
(45,327)
(36,047)
(33,411)
(34,986)
(154,727)
(129,711)
Our share of depreciation and amortization from unconsolidated real estate JVs
855
852
942
1,054
1,061
3,703
4,238
Gain on sales of real estate
(307,132)
(1)
(9,824)
(13,165)
(100,109)
(330,121)
(127,615)
Impairment of real estate – rental properties and land
1,439,303
(2)
323,870
131,090
184,532
1,894,263
192,455
Allocation to unvested restricted stock awards
(1,903)
(1,648)
(1,222)
(686)
(1,182)
(5,681)
(8,696)
Funds from operations attributable to Alexandria’s common stockholders – diluted(3)
329,206
371,168
328,881
281,574
311,592
1,310,607
1,431,750
Unrealized (gains) losses on non-real estate investments
(98,548)
(18,515)
21,938
68,145
79,776
(26,980)
112,246
Significant realized losses on non-real estate investments
103,329
(4)
103,329
Impairment of non-real estate investments
20,181
(5)
25,139
39,216
11,180
20,266
95,716
58,090
Impairment of real estate
12,619
(2)
7,189
32,154
2,032
51,962
30,613
Loss on early extinguishment of debt
107
107
Acceleration of stock compensation expense due to executive officer resignation
2,455
(6)
2,455
(Decrease) increase in provision for expected credit losses on financial instruments
(341)
285
(434)
(56)
(434)
Allocation to unvested restricted stock awards
(363)
(74)
(794)
(1,329)
(1,407)
(2,476)
(3,188)
Funds from operations attributable to Alexandria’s common stockholders – diluted, as
adjusted
$368,538
$377,825
$396,430
$392,009
$411,825
$1,534,664
$1,629,077
Refer to “Definitions and reconciliations” in the Supplemental Information for additional details.
(1)Excludes our partner’s share of gain on sale of real estate aggregating $312.8 million at our consolidated real estate joint venture at 409 and 499 Illinois Street.
(2)During 4Q25, we finalized the Company’s 2025 capital plan and established an initial 2026 capital plan to fund 2026 construction primarily through the sale of land and non-core real estate assets. As a result, we recognized the following
impairment charges to reduce the carrying amounts of certain assets to their estimated fair values less cost to sell:
Property
Submarket
Impairment
(ARE Share)
Asset Type
Assets designated as held for sale and sold in 4Q25:
601, 611, 651, 681, 685, 701, and 751 Gateway Boulevard (50% and 51% consolidated JVs)
South San Francisco
$205,957
Non-stabilized
285, 299, 307, and 345 Dorchester Avenue (60% consolidated JV)
Seaport Innovation District
149,720
Land
3029 East Cornwallis Road
Research Triangle
82,540
Land
1290 and 1300 Rancho Conejo Boulevard and 2101 Corporate Center Drive
Non-cluster
68,566
Non-stabilized
Assets designated as held for sale in 4Q25 and expected to be sold in 2026:
88 Bluxome Street
SoMa
333,446
Land
100 Edwin H. Land Boulevard
Cambridge
156,370
Land
3825 and 3875 Fabian Way
Greater Stanford
144,682
Stabilized/land
Montreal
Canada
107,056
Non-stabilized
One Hampshire Street
Cambridge
105,694
Non-stabilized
Other non-core assets designated as held for sale in 4Q25
97,891
1,451,922
Noncontrolling interest’s share of impairment in real estate from consolidated real estate JVs
265,266
Consolidated impairment of real estate
$1,717,188
(3)Calculated in accordance with standards established by the Nareit Board of Governors.
(4)In November 2025, we contributed certain publicly traded securities to an unconsolidated joint venture, which resulted in a realized loss of $103.3 million on one transaction that was previously reflected as unrealized losses within
investment income in our consolidated statement of operations. The unconsolidated joint venture sold these securities and distributed $39.9 million to us in December 2025.
(5)Primarily related to two non-real estate investments in privately held entities that do not report NAV.
(6)Relates to the resignation of an executive officer, Daniel J. Ryan, from his position as Co-President & Regional Marketing Director – San Diego.
Funds From Operations and Funds From Operations per Share (continued)
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December 31, 2025
(In thousands, except per share amounts)
The following table presents a reconciliation of net income (loss) per share attributable to Alexandria’s common stockholders, the most directly comparable financial measure presented in
accordance with GAAP, including our share of amounts from consolidated and unconsolidated real estate joint ventures, to funds from operations per share attributable to Alexandria’s common
stockholders – diluted, and funds from operations per share attributable to Alexandria’s common stockholders – diluted, as adjusted, for the periods below. Per share amounts may not add due to
rounding.
Three Months Ended
Year Ended
12/31/25
9/30/25
6/30/25
3/31/25
12/31/24
12/31/25
12/31/24
Net (loss) income per share attributable to Alexandria’s common stockholders – diluted
$(6.35)
$(1.38)
$(0.64)
$(0.07)
$(0.38)
$(8.44)
$1.80
Depreciation and amortization of real estate assets
1.65
1.73
1.81
1.80
1.70
6.99
6.20
Gain on sales of real estate
(1.80)
(0.06)
(0.08)
(0.58)
(1.94)
(0.74)
Impairment of real estate – rental properties and land
8.45
1.90
0.77
1.07
11.12
1.12
Allocation to unvested restricted stock awards
(0.02)
(0.01)
(0.01)
(0.04)
(0.06)
Funds from operations per share attributable to Alexandria’s common stockholders –
diluted
1.93
2.18
1.93
1.65
1.81
7.69
8.32
Unrealized (gains) losses on non-real estate investments
(0.58)
(0.11)
0.13
0.40
0.46
(0.16)
0.65
Significant realized losses on non-real estate investments
0.61
0.62
Impairment of non-real estate investments
0.12
0.15
0.23
0.07
0.12
0.56
0.34
Impairment of real estate
0.07
0.04
0.19
0.01
0.30
0.18
Acceleration of stock compensation expense due to executive officer resignation
0.01
0.01
Allocation to unvested restricted stock awards
(0.01)
(0.01)
(0.01)
(0.02)
Funds from operations per share attributable to Alexandria’s common stockholders –
diluted, as adjusted
$2.16
$2.22
$2.33
$2.30
$2.39
$9.01
$9.47
Weighted-average shares of common stock outstanding – diluted
Earnings per share – diluted
170,394
170,181
170,135
170,522
172,262
170,307
172,071
Funds from operations – diluted, per share
170,504
170,305
170,192
170,599
172,262
170,390
172,071
Funds from operations – diluted, as adjusted, per share
170,504
170,305
170,192
170,599
172,262
170,390
172,071
Refer to “Definitions and reconciliations” in the Supplemental Information for additional details.
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
SUPPLEMENTAL
INFORMATION
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Company Profile
December 31, 2025
Alexandria Real Estate Equities, Inc. (NYSE: ARE), an S&P 500® company, is a
best-in-class, mission-driven life science REIT making a positive and lasting impact on the
world. With our founding in 1994, Alexandria pioneered the life science real estate niche.
Alexandria is the preeminent and longest-tenured owner, operator, and developer of
collaborative Megacampus™ ecosystems in AAA life science innovation cluster locations,
including Greater Boston, the San Francisco Bay Area, San Diego, Seattle, Maryland,
Research Triangle, and New York City.
As of December 31, 2025, Alexandria has a total market capitalization of
$20.75 billion and an asset base in North America that includes 35.9 million RSF of
operating properties and 3.5 million RSF of Class A/A+ properties undergoing construction.
Alexandria has a long-standing and proven track record of developing Class A/A+
properties clustered in highly dynamic and collaborative Megacampus environments that
enhance our tenants’ ability to successfully recruit and retain world-class talent and inspire
productivity, efficiency, creativity, and success.
Alexandria also provides strategic capital to transformative life science
companies through our venture capital platform. We believe our unique business model
and diligent underwriting ensure a high-quality and diverse tenant base that results in
higher occupancy levels, longer lease terms, higher rental income, higher returns, and
greater long-term asset value. For more information on Alexandria, please visit
www.are.com.
Tenant base
Alexandria is known for our high-quality and diverse tenant base, with 53% of our 
annual rental revenue being generated from tenants that are investment-grade rated or
publicly traded large cap companies. The quality, diversity, breadth, and depth of our
significant relationships with our tenants provide Alexandria with high-quality and stable
cash flows. Alexandria’s underwriting team and long-term industry relationships positively
distinguish us from all other publicly traded REITs and real estate companies.
Executive and senior management team
Alexandria’s executive and senior management team has unique experience and
expertise in creating, owning, and operating highly dynamic and collaborative
Megacampus real estate in key life science cluster locations to catalyze innovation. From
design to development to the management of our high-quality, sustainable real estate, as
well as our ongoing cultivation of collaborative environments with unique amenities and
events, the Alexandria team has a best-in-class reputation of excellence in life science real
estate. Alexandria’s highly experienced management team includes regional market
directors with leading reputations and long-standing relationships within the life science
communities in their respective innovation clusters. We believe that our experience,
expertise, reputation, and key relationships in the real estate and life science industries
provide Alexandria significant competitive advantages in attracting new business
opportunities.
Alexandria’s executive and senior management team consists of 59
individuals averaging 24 years of real estate experience, including 13 years
with Alexandria. Our executive management team alone averages 15 years
with Alexandria.
EXECUTIVE MANAGEMENT TEAM
Joel S. Marcus
Peter M. Moglia
Executive Chairman &
Founder
Chief Executive Officer &
Chief Investment Officer
Hunter L. Kass
Hart Cole
Co-President & Regional Market Director –
Greater Boston
Co-President & Co-Regional Market
Director – Seattle
Marc E. Binda
Lawrence J. Diamond
Chief Financial Officer &
Treasurer
Co-Chief Operating Officer & Regional
Market Director – Maryland
Joseph Hakman
Jesse J. Nelson
Co-Chief Operating Officer &
Chief Strategic Transactions Officer
EVP – Regional Market Director – San
Francisco
Michael E. Boss
Bret E. Gossett
EVP – Co-Regional Market Director – San
Diego
EVP – Co-Regional Market Director &
Head of Leasing – San Diego
Blake L. Stevens
Joshua J. Mitchell
EVP – Regional Market Director –
Research Triangle
EVP – Regional Market Director – New
York
Hallie E. Kuhn
Jenna R. Foger
EVP – Capital Markets & Co-Lead – Life
Science
EVP – Co-Lead – Life Science
Jackie B. Clem
Gary D. Dean
General Counsel & Secretary
EVP – Real Estate Legal Affairs
Andres R. Gavinet
Onn C. Lee
Chief Accounting Officer
EVP – Accounting
Kristina A. Fukuzaki-Carlson
Madeleine T. Alsbrook
EVP – Business Operations
EVP – Talent Management
Gregory C. Thomas
EVP – Chief Technology Officer
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Investor Information
December 31, 2025
Corporate Headquarters
 
New York Stock Exchange Trading Symbol
 
Information Requests
26 North Euclid Avenue
 
Common stock: ARE
 
Phone:
(626) 578-0777
Pasadena, California 91101
 
 
Email:
corporateinformation@are.com
www.are.com
 
 
Website:
investor.are.com
Equity Research Coverage
Alexandria is currently covered by the following research analysts. This list may be incomplete and is subject to change as firms initiate or discontinue coverage of our company.
Please note that any opinions, estimates, or forecasts regarding our historical or predicted performance made by these analysts are theirs alone and do not represent opinions, estimates, or
forecasts of Alexandria or our management. Alexandria does not by our reference or distribution of the information below imply our endorsement of or concurrence with any opinions,
estimates, or forecasts of these analysts. Interested persons may obtain copies of analysts’ reports on their own as we do not distribute these reports. Several of these firms may, from time to
time, own our stock and/or hold other long or short positions in our stock and may provide compensated services to us.
BMO
CFRA
Green Street
RBC Capital Markets
John Kim / Juan Sanabria
Nathan Schmidt
Dylan Burzinski
Michael Carroll
(212) 885-4115 / (312) 845-4074
(646) 517-1144
(949) 640-8780
(440) 715-2649
BNP Paribas Exane
Citigroup Global Markets Inc.
J.P. Morgan Securities LLC
Robert W. Baird & Co. Incorporated
Nate Crossett / Monir Koummal
Nicholas Joseph / Seth Bergey
Anthony Paolone / Ray Zhong
Wesley Golladay / Nicholas Thillman
(646) 342-1588 / (646) 342-1554
(212) 816-1909 / (212) 816-2066
(212) 622-6682 / (212) 622-5411
(216) 737-7510 / (414) 298-5053
BofA Securities
Citizens
Jefferies
Farrell Granath / Jeff Spector
Aaron Hecht / Linda Fu
Joe Dickstein / Katie Elders
(646) 855-1351 / (646) 855-1363
(415) 835-3963 / (415) 869-4411
(212) 778-8771 / (917) 421-1968
BTIG, LLC
Deutsche Bank AG
Mizuho Securities USA LLC
Tom Catherwood / Michael Tompkins
Tayo Okusanya / Samuel Ohiomah
Vikram Malhotra / Jyoti Yadav
(212) 738-6140 / (212) 527-3566
(212) 250-9284 / (212) 250-0057
(212) 282-3827 / (212) 471-2683
Cantor Fitzgerald
Evercore ISI
Morgan Stanley & Co. LLC
Richard Anderson / Jeffrey Carr
Steve Sakwa / James Kammert
Ronald Kamdem / Derrick Metzler
(929) 441-6927 / (929) 709-0434
(212) 446-9462 / (312) 705-4233
(212) 296-8319 / (212) 761-3366
Fixed Income Research Coverage
Rating Agencies
Barclays Capital Inc.
J.P. Morgan Securities LLC
Moody’s Ratings
 
S&P Global Ratings
Srinjoy Banerjee / Ishaan Pandya
Mark Streeter / Tyler Schachner
(212) 553-0376
 
Michael Souers
(212) 526-3521 / (212) 526-2970
(212) 834-5086 / (212) 834-2238
 
(212) 438-2508
CreditSights
Mizuho Securities USA LLC
Nicholas Moglia
Thierry Perrein
(212) 340-3886
(212) 205-7665
Financial and Asset Base Highlights
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December 31, 2025
(Dollars in thousands, except per share amounts)
 
Three Months Ended (unless stated otherwise)
12/31/25
9/30/25
6/30/25
3/31/25
12/31/24
Selected financial data from consolidated financial statements and related information
Rental revenues
$538,330
$541,070
$553,377
$552,112
$566,535
Tenant recoveries
$190,542
$194,779
$183,902
$191,063
$196,714
General and administrative expenses
$28,020
$29,224
$29,128
$30,675
$32,730
General and administrative expenses as a percentage of net operating income –
trailing 12 months
5.6%
5.7%
6.3%
6.9%
7.6%
Operating margin
69%
68%
71%
70%
70%
Adjusted EBITDA margin
70%
71%
71%
71%
72%
Adjusted EBITDA – quarter annualized
$2,097,444
$2,130,008
$2,174,160
$2,165,632
$2,273,480
Adjusted EBITDA – trailing 12 months
$2,141,811
$2,185,820
$2,208,226
$2,218,722
$2,228,921
Net debt at end of period
$11,921,114
$13,085,745
$12,844,726
$12,687,856
$11,762,176
Net debt and preferred stock to Adjusted EBITDA – quarter annualized
5.7x
6.1x
5.9x
5.9x
5.2x
Net debt and preferred stock to Adjusted EBITDA – trailing 12 months
5.6x
6.0x
5.8x
5.7x
5.3x
Total debt and preferred stock at end of period
$12,400,555
$13,593,541
$13,294,100
$13,090,834
$12,244,374
Gross assets at end of period
$40,209,360
$43,791,893
$43,770,007
$43,486,989
$43,152,628
Total debt and preferred stock to gross assets at end of period
31%
31%
30%
30%
28%
Fixed-charge coverage ratio – quarter annualized
3.7x
3.9x
4.1x
4.3x
4.3x
Fixed-charge coverage ratio – trailing 12 months
4.0x
4.1x
4.3x
4.4x
4.5x
Unencumbered net operating income as a percentage of total net operating income
100.0%
100.0%
99.7%
99.8%
99.9%
Closing stock price at end of period
$48.94
$83.34
$72.63
$92.51
$97.55
Common shares outstanding (in thousands) at end of period
170,538
170,339
170,146
170,130
172,203
Total equity capitalization at end of period
$8,346,123
$14,196,059
$12,357,709
$15,738,715
$16,798,446
Total market capitalization at end of period
$20,746,678
$27,789,600
$25,651,809
$28,829,549
$29,042,820
Dividend per share – quarter/annualized
$0.72/$2.88
$1.32/$5.28
$1.32/$5.28
$1.32/$5.28
$1.32/$5.28
Dividend payout ratio for the quarter
33%
60%
57%
57%
55%
Dividend yield – annualized
5.9%
6.3%
7.3%
5.7%
5.4%
Amounts related to operating leases:
Operating lease liabilities at end of period
$360,543
$361,986
$363,419
$371,412
$507,127
Rent expense
$8,566
$10,645
$12,139
$11,666
$10,685
Capitalized interest
$81,845
$86,091
$82,423
$80,065
$81,586
Average real estate basis capitalized during the period
$8,046,984
$8,407,332
$8,107,180
$8,026,566
$8,118,010
Weighted-average interest rate for capitalization of interest during the period
4.07%
4.10%
4.07%
3.99%
4.02%
Refer to “Definitions and reconciliations” in the Supplemental Information for additional details.
Financial and Asset Base Highlights (continued)
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December 31, 2025
(Dollars in thousands, except annual rental revenue per occupied RSF amounts)
 
Three Months Ended (unless stated otherwise)
12/31/25
9/30/25
6/30/25
3/31/25
12/31/24
Amounts included in funds from operations and non-revenue-enhancing capital expenditures
Straight-line rent revenue
$14,096
$18,821
$18,536
$22,023
$17,653
Amortization of acquired below-market leases
$5,889
$6,456
$10,196
$15,222
$15,512
Amortization of deferred revenue related to tenant-funded and -built landlord improvements
$5,264
$5,455
$2,401
$1,651
$1,214
Straight-line rent expense on ground leases
$116
$114
$87
$149
$1,021
Cash payment for ground lease extension
$
$
$
$(135,000)
$(135,000)
Stock compensation expense
$8,232
$10,293
$12,530
$10,064
$12,477
Amortization of loan fees
$4,481
$4,505
$4,615
$4,691
$4,620
Amortization of debt discounts
$327
$325
$335
$349
$333
Non-revenue-enhancing capital expenditures:
Building improvements
$4,372
$3,948
$4,622
$3,789
$4,313
Tenant improvements and leasing commissions
$26,494
$16,707
$23,971
$73,483
$81,918
Funds from operations attributable to noncontrolling interests
$77,922
$80,236
$80,860
$81,012
$76,111
Operating statistics and related information (at end of period)
Number of properties – North America
340
375
384
386
391
RSF – North America (including development and redevelopment projects under construction)
39,449,372
42,887,964
43,699,922
43,687,343
44,124,001
Total square footage – North America
59,382,079
66,417,026
67,220,337
68,518,184
69,289,411
Annual rental revenue per occupied RSF – North America
$59.97
$58.94
$58.68
$58.38
$56.98
Occupancy of operating properties – North America
90.9%
(1)
90.6%
90.8%
91.7%
94.6%
Occupancy of operating and redevelopment properties – North America
86.9%
85.8%
86.2%
86.9%
89.7%
Weighted-average remaining lease term (in years)
7.5
7.5
7.4
7.6
7.5
Total leasing activity – RSF
1,220,944
1,171,344
769,815
1,030,553
1,310,999
Lease renewals and re-leasing of space – change in new rental rates over expiring rates:
Rental rate changes
(9.9)%
15.2%
5.5%
18.5%
18.1%
Rental rate changes (cash basis)
(5.2)%
6.1%
6.1%
7.5%
3.3%
RSF (included in total leasing activity above)
821,289
354,367
483,409
884,408
1,024,862
Previously vacant leasing activity – RSF
393,376
256,633
154,638
139,715
273,138
Top 20 tenants:
Annual rental revenue
$725,559
$768,528
$795,244
$754,354
$741,965
Annual rental revenue from investment-grade or publicly traded large cap tenants
84%
90%
89%
87%
92%
Weighted-average remaining lease term (in years)
9.7
9.4
9.4
9.6
9.3
Same property performance – percentage change over comparable quarter from prior year:
Net operating income changes
(6.0)%
(2)
(6.0)%
(5.4)%
(3.1)%
0.6%
Net operating income changes (cash basis)
(1.7)%
(2)
(3.1)%
2.0%
5.1%
6.3%
Refer to “Definitions and reconciliations” in the Supplemental Information for additional details.
(1)Refer to page 2 in the Earnings Press Release and “Summary of properties and occupancy” in the Supplemental Information for additional details.
(2)Refer to “Same property performance” in the Supplemental Information for additional details.
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High-Quality and Diverse Client Base
December 31, 2025
Stable Cash Flows From Our High-Quality and Diverse Mix of Tenants
Investment-Grade or Publicly Traded
Large Cap Tenants
84%
of ARE’s Top 20 Tenant
Annual Rental Revenue
53%
of ARE’s Total
Annual Rental Revenue
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Life Science Product,
Service, and Device
Multinational
Pharmaceutical
Public
Biotechnology –
Approved or
Marketed
Other(1)
Advanced
Technologies(2)
Public
Biotechnology –
Preclinical or
Clinical Stage
Government
Institutions
Biomedical
Institutions(3)
Private
Biotechnology
Percentage of ARE’s Annual Rental Revenue
As of December 31, 2025. Annual rental revenue represents amounts in effect as of December 31, 2025. Refer to “Definitions and reconciliations” in the Supplemental Information for additional details, including our methodology of calculating
annual rental revenue from unconsolidated real estate joint ventures.
(1)Represents the percentage of our annual rental revenue generated by professional services, finance, construction/real estate companies, and retail-related tenants.
(2)71% of our annual rental revenue from advanced technologies tenants is from investment-grade or publicly traded large cap tenants.
(3)82% of our annual rental revenue from biomedical institutions is from investment-grade or publicly traded large cap tenants.
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Key Operating Metrics
December 31, 2025
Same Property Performance:
Net Operating Income Changes
Rental Rate Growth:
Renewed/Re-Leased Space
Margins(1)
Favorable Lease Structure(2)
Operating
Adjusted EBITDA
Strategic Lease Structure by Owner and Operator
of Collaborative Megacampus Ecosystems
69%
70%
Increasing cash flows
Percentage of leases containing
annual rent escalations
97%
Stable cash flows
Long-Duration Lease Terms(3)
Percentage of triple net leases
92%
9.7 Years
7.5 Years
Lower capex burden
Percentage of leases providing for the
recapture of capital expenditures
92%
Top 20 Tenants
All Tenants
chart-dd31d154c1b148ef830.gif
chart-3930a7501b774816bd3.gif
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(3.5)%
2024
2025
Refer to “Same property performance” and “Definitions and reconciliations” in the Supplemental Information for additional details. “Definitions and reconciliations” contains the definition of “Net operating income” and its reconciliation
from the most directly comparable financial measure presented in accordance with GAAP.
(1)For the three months ended December 31, 2025.
(2)Percentages calculated based on our annual rental revenue in effect as of December 31, 2025.
(3)Represents the weighted-average remaining term based on annual rental revenue in effect as of December 31, 2025.
Same Property Performance
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December 31, 2025
(Dollars in thousands)
December 31, 2025
December 31, 2025
Same Property Financial Data
Three Months
Ended
Year Ended
Same Property Statistical Data
Three Months
Ended
Year Ended
Percentage change over comparable period from prior year:
Number of same properties
286
282
Net operating income changes
(6.0)%
(3.5)%
Rentable square feet
30,622,240
29,774,548
Net operating income changes (cash basis)
(1.7)%
0.9%
(1)
Occupancy – current-period average
91.0%
92.5%
Operating margin
67%
68%
Occupancy – same-period prior-year average
95.5%
95.2%
 
Three Months Ended December 31,
Year Ended December 31,
2025
2024
$ Change
% Change
2025
2024
$ Change
% Change
Income from rentals:
Same properties
$425,975
$451,251
$(25,276)
(5.6)%
$1,687,734
$1,732,019
$(44,285)
(2.6)%
Non-same properties
112,355
115,284
(2,929)
(2.5)
497,155
572,320
(75,165)
(13.1)
Rental revenues
538,330
566,535
(28,205)
(5.0)
2,184,889
2,304,339
(119,450)
(5.2)
Same properties
163,222
160,984
2,238
1.4
627,224
594,471
32,753
5.5
Non-same properties
27,320
35,730
(8,410)
(23.5)
133,062
150,896
(17,834)
(11.8)
Tenant recoveries
190,542
196,714
(6,172)
(3.1)
760,286
745,367
14,919
2.0
Income from rentals
728,872
763,249
(34,377)
(4.5)
2,945,175
3,049,706
(104,531)
(3.4)
Same properties
793
335
458
136.7
1,791
1,267
524
41.4
Non-same properties
24,749
25,361
(612)
(2.4)
79,590
65,421
14,169
21.7
Other income
25,542
25,696
(154)
(0.6)
81,381
66,688
14,693
22.0
Same properties
589,990
612,570
(22,580)
(3.7)
2,316,749
2,327,757
(11,008)
(0.5)
Non-same properties
164,424
176,375
(11,951)
(6.8)
709,807
788,637
(78,830)
(10.0)
Total revenues
754,414
788,945
(34,531)
(4.4)
3,026,556
3,116,394
(89,838)
(2.9)
Same properties
195,291
192,768
2,523
1.3
752,481
706,904
45,577
6.4
Non-same properties
37,252
47,664
(10,412)
(21.8)
170,124
202,361
(32,237)
(15.9)
Rental operations
232,543
240,432
(7,889)
(3.3)
922,605
909,265
13,340
1.5
Same properties
394,699
419,802
(25,103)
(6.0)
1,564,268
1,620,853
(56,585)
(3.5)
Non-same properties
127,172
128,711
(1,539)
(1.2)
539,683
586,276
(46,593)
(7.9)
Net operating income
$521,871
$548,513
$(26,642)
(4.9)%
(2)
$2,103,951
$2,207,129
$(103,178)
(4.7)%
(2)
Net operating income – same properties
$394,699
$419,802
$(25,103)
(6.0)%
$1,564,268
$1,620,853
$(56,585)
(3.5)%
Straight-line rent revenue
(5,296)
(21,637)
16,341
(75.5)
(25,078)
(94,232)
69,154
(73.4)
Amortization of acquired below-market leases and deferred
revenue related to tenant-funded and -built landlord
improvements
(9,503)
(11,504)
2,001
(17.4)
(36,763)
(37,512)
749
(2.0)
Net operating income – same properties (cash basis)
$379,900
$386,661
$(6,761)
(1.7)%
$1,502,427
$1,489,109
$13,318
0.9%
Refer to “Same property comparisons” under “Definitions and reconciliations” in the Supplemental Information for additional details, including a reconciliation of same properties to total properties. “Definitions and reconciliations” also
contains definitions of “Tenant recoveries” and “Net operating income” and their respective reconciliations from the most directly comparable financial measures presented in accordance with GAAP.
(1)Includes the impact of initial free rent concessions that burned off after January 1, 2024 for development and redevelopment projects that were placed into service in 2023, and accordingly are part of our same property pool for the
year ended December 31, 2025, including at 325 Binney Street in our Cambridge submarket and 15 Necco Street in our Seaport Innovation District submarket. Excluding the impact of these initial free rent concessions, same property
net operating income (cash basis) for the year ended December 31, 2025 would have decreased by 1.4%.
(2)Decrease in net operating income includes the impact of operating properties disposed of after January 1, 2024. Excluding these dispositions, net operating income for the three months ended December 31, 2025 and the year ended
December 31, 2025 would have decreased by 1.7%, and would have increased by 0.9%, respectively, compared to the corresponding periods in 2024.
Leasing Activity
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December 31, 2025
(Dollars per RSF)
Three Months Ended
Year Ended
Year Ended
December 31, 2025
December 31, 2025
December 31, 2024
Including
Straight-Line Rent
Cash Basis
Including
Straight-Line Rent
Cash Basis
Including
Straight-Line Rent
Cash Basis
Leasing activity:
Renewed/re-leased space(1)
 
 
Rental rate changes
(9.9)%
(2)
(5.2)%
(2)
7.0%
3.5%
16.9%
7.2%
New rates
$38.58
$42.11
$52.71
$53.66
$65.48
$64.18
Expiring rates
$42.82
$44.44
$49.27
$51.87
$56.01
$59.85
RSF
821,289
2,543,473
3,888,139
Tenant improvements/leasing commissions
$32.26
$55.34
$46.89
Weighted-average lease term
5.9 years
9.0 years
8.5 years
Previously vacant/developed/redeveloped space leased(3)
New rates
$64.08
$62.55
$72.30
$67.56
$59.44
$57.34
Previously vacant RSF
393,376
944,362
672,474
Developed/redeveloped RSF
6,279
704,821
493,341
Weighted-average lease term
8.8 years
13.8 years
10.0 years
Leasing activity summary (totals):
New rates
$46.93
$48.80
$60.42
$59.13
$64.16
$62.68
RSF
1,220,944
4,192,656
5,053,954
Weighted-average lease term
7.6 years
11.9 years
8.9 years
Lease expirations(1)
Expiring rates
$44.66
$46.13
$54.22
$55.56
$53.82
$57.24
RSF
911,029
4,460,081
5,005,638
Leasing activity includes 100% of results for properties in North America in which we have an investment.
(1)Excludes month-to-month leases aggregating 58,516 RSF and 136,131 RSF as of December 31, 2025 and 2024, respectively. During the year ended December 31, 2025, we granted free rent concessions averaging 1.5
months per annum.
(2)Includes (i) a one-year lease extension aggregating 247,743 RSF with an investment-grade-rated government institution tenant at an office property in Canada and (ii) a 7.4-year lease aggregating 83,354 RSF with an
anchor tenant at one property in our Sorrento Mesa submarket. At acquisition, the office property in Canada was originally targeted for a future change in use, but we instead renewed the existing tenant through the
beginning of 2027, with no incremental capital investment. We continue to evaluate business strategy for this property, including the potential sale of the asset, subject to market conditions. Excluding these leases, rental
rates for renewed and re-leased space for the three months ended December 31, 2025 increased by 4.6% and decreased by 5.0% (cash basis).
(3)Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” in the Supplemental Information for additional details, including total project costs.
Leasing Activity – Tenant Mix
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December 31, 2025
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Alexandria’s Leasing Volume Is Driven
by Our Diverse Tenant Mix
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Life Science
Product, Service,
and Device
Life Science
Product, Service,
and Device
Multinational
Pharmaceutical
Public
Biotechnology
Multinational
Pharmaceutical
4Q25
2025
Private
Biotechnology
Public
Biotechnology
Other
Advanced
Technology
Other
Biomedical
Institutions
Private
Biotechnology
Advanced
Technology
Biomedical
Institutions
Contractual Lease Expirations
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December 31, 2025
Year
RSF
Percentage of Occupied RSF
Annual Rental Revenue (per RSF)(1)
Percentage of Annual Rental Revenue
2026
(2)
2,900,665
9.3%
$52.73
8.2%
2027
3,220,834
10.3%
$54.52
9.4%
2028
3,848,085
12.4%
$51.80
10.7%
2029
1,741,417
5.6%
$46.91
4.4%
2030
2,482,633
8.0%
$43.28
5.7%
2031
3,550,982
11.4%
$54.17
10.3%
2032
864,810
2.8%
$58.02
2.7%
2033
2,164,696
6.9%
$50.94
5.9%
2034
2,733,787
8.8%
$67.66
9.9%
2035
1,042,126
3.3%
$57.39
3.2%
Thereafter
6,601,764
21.2%
$84.09
29.6%
Market
2026 Contractual Lease Expirations (in RSF)
Annual
Rental
Revenue
(per RSF)(1)
2027 Contractual Lease Expirations (in RSF)
Annual
Rental
Revenue
(per RSF)(1)
Leased
Negotiating/
Anticipating
Targeted for
Future
Development/
Redevelopment
Remaining
Expiring
Leases
Total(2)
Leased
Negotiating/
Anticipating
Targeted for
Future
Development/
Redevelopment
Remaining
Expiring Leases
Total
Greater Boston
144,451
248,627
393,078
$44.01
50,649
179,430
230,079
$94.88
San Francisco Bay Area
6,527
22,000
286,652
315,179
69.98
1,873
215,684
217,557
70.96
San Diego
49,791
52,620
(3)
153,477
255,888
54.62
339,716
339,716
43.71
Seattle
32,500
150,145
182,645
28.00
4,320
25,898
486,950
517,168
43.59
Maryland
171,239
173,729
344,968
29.48
261,550
261,550
27.38
Research Triangle
42,318
6,439
99,209
147,966
43.66
34,910
242,303
277,213
34.74
New York City
35,256
39,659
74,915
71.65
98,299
98,299
91.95
Texas
91,711
91,711
26.10
Non-cluster/other markets
24,567
24,567
59.21
11,418
11,418
N/A
Subtotal
432,291
78,230
52,620
1,176,065
1,739,206
47.11
91,752
25,898
1,927,061
2,044,711
50.43
Key lease expirations with
expected downtime
140,986
9,836
1,010,637
(4)
1,161,459
(4)
61.14
1,176,123
1,176,123
(5)
61.61
Total
573,277
88,066
52,620
2,186,702
2,900,665
$52.73
91,752
25,898
3,103,184
3,220,834
$54.52
Percentage of expiring leases
20%
3%
2%
75%
100%
3%
1%
0%
96%
100%
Contractual lease expirations for properties classified as held for sale as of December 31, 2025 are excluded from the information on this page.
(1)Represents amounts in effect as of December 31, 2025.
(2)Excludes month-to-month leases aggregating 58,516 RSF as of December 31, 2025.
(3)Relates to a single-tenant, 100% pre-leased development project aggregating 466,598 RSF that expands the existing Campus Point by Alexandria Megacampus. At the beginning of 2026, the tenant will vacate 52,620 RSF from an
existing building, which generated annual rental revenue of $4.1 million as of 4Q25, to allow for the demolition and development of the new, build-to-suit life science building at this site. Refer to “New Class A/A+ development and
redevelopment properties: current projects” in the Supplemental Information for additional details.
(4)Key lease expirations with expected downtime represent space expected to become vacant at lease expiration and re-leased to new tenants. We have identified prospects or have early discussions with prospective tenants for 468,470
RSF of the 1.0 million RSF listed under remaining expiring leases. We continue to evaluate business plans and re-leasing strategies for these projects to maximize occupancy and rental revenue. We expect downtime for 2026 key lease
expirations to be approximately 6 to 24 months on a weighted-average basis, and we expect these properties to remain operating properties.
Property or Campus
Submarket
RSF
% of Leased/
Negotiating
Weighted Average
Expiration Date
Located on
Megacampus
Annual Rental Revenue
From Lease Expirations/
Known Vacancies
Alexandria Stanford Life Science District
Greater Stanford
137,970
—%
June 2026
$12,899
One Alexandria Square
Torrey Pines
118,225
38
January 2026
X
10,064
Alexandria Center® at One Kendall Square
Cambridge
92,775
May 2026
X
7,783
9625 Towne Centre Drive
University Town Center
163,648
January 2026
6,520
5810/5820 Nancy Ridge Drive
Sorrento Mesa
83,354
100
January 2026
3,389
Alexandria Center® at Kendall Square
Cambridge
45,636
January 2026
X
4,564
Remaining
Various
519,851
4
May 2026
(6)
25,792
1,161,459
13%
April 2026
$71,011
(5)Represents key 2027 lease expirations with expected downtime primarily in our Greater Boston, San Francisco Bay Area, and San Diego markets aggregating 1.2 million RSF with a weighted-average expiration date in March 2027 and
annual rental revenue aggregating $72 million. Included in these expirations are seven leases aggregating 531,984 RSF and $42.3 million in annual rental revenue with four separate tenants that will relocate to our current active
development and redevelopment projects upon completion of their tenant improvements. On a combined basis, these tenants will expand their footprint within our portfolio by over 41%. Additionally, we have identified prospects or have
early discussions with prospective tenants for 302,028 RSF of the total 1.2 million RSF. We expect downtime to be approximately 9 to 24 months on a weighted-average basis, and we expect these properties to remain operating properties.
(6)Approximately 69% of the 519,851 RSF expiring leases are located on a Megacampus.
Top 20 Tenants
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December 31, 2025
(Dollars in thousands, except average market cap amounts)
84% of Top 20 Tenant Annual Rental Revenue Is From Investment-Grade
or Publicly Traded Large Cap Tenants(1)
Tenant
Remaining Lease
Term(1) (in years)
Aggregate
RSF
Annual Rental
Revenue(1)
Percentage of
Annual Rental
Revenue(1)
Investment-Grade
Credit Ratings
Average
Market Cap
(in billions)
Moody’s
S&P
1
Bristol-Myers Squibb Company
5.6
1,344,987
$116,140
6.1%
A2
A
$102.64
2
Eli Lilly and Company
9.3
1,000,591
84,928
4.5
Aa3
A+
$784.24
3
Moderna, Inc.
12.9
462,100
71,571
3.8
$11.32
4
Takeda Pharmaceutical Company Limited
9.4
549,759
47,899
2.5
Baa1
BBB+
$46.08
5
Eikon Therapeutics, Inc.(2)
13.1
311,806
40,005
2.1
$
6
AstraZeneca PLC
6.1
440,087
39,413
2.1
A1
A+
$237.13
7
Illumina, Inc.
5.8
792,687
29,977
1.6
Baa3
BBB
$15.91
8
Novartis AG
2.1
377,095
29,463
1.6
Aa3
AA-
$251.26
9
United States Government
4.6
414,499
29,243
(3)
1.5
Aaa
AA+
$
10
Uber Technologies, Inc.
56.8
(4)
1,009,188
27,831
1.5
Baa1
BBB
$176.44
11
Boston Children's Hospital
11.2
309,231
26,294
1.4
Aa2
AA
$
12
Sanofi
5.0
267,278
21,851
1.2
Aa3
AA
$125.29
13
Alphabet Inc.
2.4
418,600
21,837
1.1
Aa2
AA+
$2,562.42
14
New York University
6.6
218,983
21,110
1.1
Aa2
AA-
$
15
Cloud Software Group Holdings, Inc.
0.7
(5)
216,278
20,553
1.1
$
16
Massachusetts Institute of Technology
4.0
242,428
20,529
1.1
Aaa
AAA
$
17
Charles River Laboratories, Inc.
9.7
242,693
20,207
1.1
$7.97
18
Merck & Co., Inc.
8.0
308,356
19,610
1.0
Aa3
A+
$219.09
19
Vaxcyte, Inc.
9.0
230,755
18,692
1.0
$6.09
20
Altos Labs, Inc.(6)
15.3
158,990
18,406
1.0
$
Total/weighted-average
9.7
(4)
9,316,391
$725,559
38.4%
Annual rental revenue and RSF include 100% of each property managed by us in North America. Refer to “Annual rental revenue” and “Investment-grade or publicly traded large cap tenants” under “Definitions and reconciliations” in the
Supplemental Information for additional details, including our methodology of calculating annual rental revenue from unconsolidated real estate joint ventures and average market capitalization, respectively.
(1)Based on annual rental revenue in effect as of December 31, 2025.
(2)Eikon Therapeutics, Inc. is a private biotechnology company led by renowned biopharmaceutical executive Roger Perlmutter, formerly an executive vice president at Merck & Co., Inc. As of February 25, 2025, the company has raised over
$1.16 billion in private venture capital funding.
(3)Includes leases, which are not subject to annual appropriations, with governmental entities such as the NIH and the General Services Administration. Approximately 2% of the annual rental revenue derived from our leases with the United
States Government is cancellable prior to the lease expiration date.
(4)Includes (i) ground leases for land at 1455 and 1515 Third Street (two buildings aggregating 422,980 RSF) and (ii) leases at 1655 and 1725 Third Street (two buildings aggregating 586,208 RSF) in our Mission Bay submarket owned by
our unconsolidated real estate joint venture in which we have an ownership interest of 10%. Annual rental revenue is presented using 100% of the annual rental revenue from our consolidated properties and our share of annual rental
revenue from our unconsolidated real estate joint ventures. Excluding these ground leases, the weighted-average remaining lease term for our top 20 tenants was 7.9 years as of December 31, 2025.
(5)Represents one lease encompassing three properties located on the Alexandria Stanford Life Science District campus, which we acquired in 2022 and for which we are evaluating business strategy based on market conditions. This lease
with Cloud Software Group, Inc. (formerly known as TIBCO Software, Inc.) was in place when we acquired the properties, of which 137,970 RSF has lease expirations through 2026. Refer to “Contractual lease expirations” in the
Supplemental Information for additional details.
(6)Altos Labs, Inc. is a private biotechnology company led by Hal Barron, M.D., former Chief Scientific Officer of GlaxoSmithKline. Altos Labs is backed by a group of prominent long-term investors and has raised $3.0 billion in private
funding.
Summary of Properties and Occupancy
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December 31, 2025
(Dollars in thousands, except per RSF amounts)
Summary of properties
RSF
Number of
Properties
Annual Rental Revenue
Market
Operating
Development
Redevelopment
Total
% of Total
Total
% of Total
Per RSF
Greater Boston
9,220,527
583,407
1,383,691
11,187,625
28%
62
$709,347
37%
$89.07
San Francisco Bay Area
6,131,550
212,796
107,250
6,451,596
16
53
347,448
18
68.83
San Diego
6,093,824
975,135
7,068,959
19
59
320,581
18
54.14
Seattle
2,926,554
227,577
3,154,131
8
42
121,514
6
46.95
Maryland
3,732,888
3,732,888
9
48
153,169
8
44.35
Research Triangle
3,435,634
3,435,634
9
34
94,667
5
28.94
New York City
729,461
729,461
2
2
66,085
3
93.96
Texas
1,646,187
73,298
1,719,485
4
13
36,866
2
28.02
Non-cluster/other markets(1)
414,216
414,216
1
7
12,379
1
32.75
Properties held for sale
1,555,377
1,555,377
4
20
37,697
2
36.46
North America
35,886,218
1,998,915
1,564,239
39,449,372
100%
340
$1,899,753
100%
$59.97
3,563,154
Summary of occupancy
 
Operating Properties
Operating and Redevelopment Properties
Market
12/31/25
9/30/25
12/31/24
12/31/25
9/30/25
12/31/24
Greater Boston
86.4%
86.8%
94.8%
75.1%
73.6%
80.8%
San Francisco Bay Area
90.9
90.4
93.3
89.4
86.4
89.1
San Diego
97.2
95.2
96.3
97.2
95.2
96.3
Seattle
88.4
(2)
90.1
92.4
88.4
90.1
92.4
Maryland
93.6
93.9
95.7
93.6
93.9
95.7
Research Triangle
95.2
94.9
97.4
95.2
94.9
97.4
New York City
96.4
98.3
88.4
96.4
98.3
88.4
Texas
79.9
79.9
95.5
76.5
76.5
91.8
Subtotal
90.9
90.8
94.8
86.9
85.9
90.0
Canada
N/A
(3)
90.3
95.9
N/A
85.4
82.9
Non-cluster/other markets
91.2
(1)
69.6
72.5
91.2
69.6
72.5
North America
90.9%
(4)
90.6%
94.6%
86.9%
85.8%
89.7%
(1)Includes one property aggregating 247,743 RSF previously included in our Canada market.
(2)Decline in occupancy primarily related to temporary vacancy from one lease expiration aggregating 50,552 RSF in our Bothell submarket. This space is already re-leased, with occupancy expected to commence in 1Q26.
(3)10 properties in Canada were designated as held for sale in 4Q25 and the remaining one property was reclassified into our non-cluster market.
(4)Includes temporary vacancies as of December 31, 2025 aggregating 899,259 RSF, or 2.5% of total operating RSF, primarily in the Greater Boston, San Francisco Bay Area, and Seattle markets, which are leased and expected
to be occupied upon completion of building and/or tenant improvements. The weighted-average expected delivery date is approximately August 2026 and the expected annual rental revenue is approximately $52 million.
Property Listing
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December 31, 2025
(Dollars in thousands)
Our Megacampus Properties Account for 78% of Our Annual Rental Revenue
Market / Submarket / Address
RSF
Number of
Properties
Annual
Rental
Revenue
Occupancy Percentage
Operating
Operating and
Redevelopment
Operating
Development
Redevelopment
Total
Greater Boston
Cambridge/Inner Suburbs
Megacampus: Alexandria Center® at Kendall Square
2,213,866
2,213,866
8
$212,458
93.7%
93.7%
50(1), 60(1), 75/125(1), 90, 100(1), and 225(1) Binney Street, 140 First Street, and
300 Third Street(1)
Megacampus: Alexandria Center® at One Kendall Square
1,294,598
1,294,598
11
136,034
91.2
91.2
One Kendall Square (Buildings 100, 200, 300, 400, 500, 600/700, 1400, 1800,
and 2000), and 325 and 399 Binney Street
Megacampus: Alexandria Technology Square®
1,192,075
1,192,075
7
79,341
73.9
73.9
100, 200, 300, 400, 500, 600, and 700 Technology Square
Megacampus: The Arsenal on the Charles
787,760
333,758
1,121,518
13
46,020
78.0
54.8
  311, 321, and 343 Arsenal Street, 300, 400, and 500 North Beacon Street,
1, 2, 3, and 4 Kingsbury Avenue, and 100, 200, and 400 Talcott Avenue
Megacampus: 480 Arsenal Way, 446, 458, and 500 Arsenal Street, and 99
Coolidge Avenue(1)
386,780
191,396
578,176
5
26,298
91.4
91.4
Cambridge/Inner Suburbs
5,875,079
191,396
333,758
6,400,233
44
500,151
86.9
82.2
Fenway
Megacampus: Alexandria Center® for Life Science – Fenway
1,452,183
392,011
1,844,194
3
104,651
79.2
79.2
401 and 421 Park Drive and 201 Brookline Avenue
Seaport Innovation District
5 and 15(1) Necco Street
459,395
459,395
2
47,019
97.0
97.0
Route 128
Megacampus: Alexandria Center® for Life Science – Waltham
465,981
596,064
1,062,045
5
38,566
97.8
42.9
40, 50, and 60 Sylvan Road, 35 Gatehouse Drive, and 840 Winter Street
19, 225, and 235 Presidential Way
585,226
585,226
3
14,194
97.0
97.0
Route 128
1,051,207
596,064
1,647,271
8
52,760
97.4
62.1
Other
Megacampus: 30, 200, and 3000 Minuteman Road
382,663
453,869
836,532
5
4,766
62.5
28.6
Greater Boston
9,220,527
583,407
1,383,691
11,187,625
62
$709,347
86.4%
75.1%
Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” and “Definitions and reconciliations” in the Supplemental Information for additional details.
(1)We own a partial interest in this property through a real estate joint venture. Refer to “Joint venture financial information” in the Supplemental Information for additional details.
Property Listing (continued)
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December 31, 2025
(Dollars in thousands)
Market / Submarket / Address
RSF
Number of
Properties
Annual
Rental
Revenue
Occupancy Percentage
Operating
Operating and
Redevelopment
Operating
Development
Redevelopment
Total
San Francisco Bay Area
Mission Bay
Megacampus: Alexandria Center® for Science and Technology –
Mission Bay(1)
1,557,403
212,796
1,770,199
8
$65,400
96.0%
96.0%
1455(2), 1515(2), 1655, and 1725 Third Street, 1450, 1500, and 1700 Owens
Street, and 455 Mission Bay Boulevard South
Mission Bay
1,557,403
212,796
1,770,199
8
65,400
96.0
96.0
South San Francisco
Megacampus: Alexandria Center® for Advanced Technologies – South San
Francisco
812,453
107,250
919,703
5
42,600
79.0
69.8
213(1), 249, 259, 269, and 279 East Grand Avenue
Alexandria Center® for Life Science – South San Francisco
504,232
504,232
3
28,642
83.0
83.0
201 Haskins Way and 400 and 450 East Jamie Court
Megacampus: Alexandria Center® for Advanced Technologies – Tanforan
445,232
445,232
2
2,365
100.0
100.0
1122 and 1150 El Camino Real
Alexandria Technology Center® – Gateway
326,197
326,197
5
19,461
89.7
89.7
600, 630, 650, 901, and 951 Gateway Boulevard
Alexandria Center® for Life Science – Millbrae(1)
285,346
285,346
1
37,003
100.0
100.0
230 Harriet Tubman Way
500 Forbes Boulevard(1)
155,685
155,685
1
10,908
100.0
100.0
South San Francisco
2,529,145
107,250
2,636,395
17
140,979
88.5
84.9
Greater Stanford
Megacampus: Alexandria Center® for Life Science – San Carlos
738,038
738,038
9
46,677
91.4
91.4
825, 835, 960, and 1501-1599 Industrial Road
Alexandria Stanford Life Science District
705,787
705,787
9
53,480
86.8
86.8
3160, 3165, 3170, and 3181 Porter Drive and 3301, 3303, 3305, 3307, and
3330 Hillview Avenue
3412, 3420, 3440, 3450, and 3460 Hillview Avenue
340,103
340,103
5
24,429
86.5
86.5
2475 and 2625/2627/2631 Hanover Street and 1450 Page Mill Road
198,548
198,548
3
13,751
100.0
100.0
2100 and 2200 Geng Road
62,526
62,526
2
2,732
100.0
100.0
Greater Stanford
2,045,002
2,045,002
28
141,069
90.1
90.1
San Francisco Bay Area
6,131,550
212,796
107,250
6,451,596
53
$347,448
90.9%
89.4%
Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” and “Definitions and reconciliations” in the Supplemental Information for additional details.
(1)We own a partial interest in this property through a real estate joint venture. Refer to “Joint venture financial information” in the Supplemental Information for additional details.
(2)We own 100% of this property.
Property Listing (continued)
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December 31, 2025
(Dollars in thousands)
Market / Submarket / Address
RSF
Number of
Properties
Annual
Rental
Revenue
Occupancy Percentage
Operating
Operating and
Redevelopment
Operating
Development
Redevelopment
Total
San Diego
Torrey Pines
Megacampus: One Alexandria Square
1,090,906
1,090,906
10
$77,138
96.5%
96.5%
3115 and 3215(1) Merryfield Row, 3010, 3013, and 3033 Science Park Road,
10935, 10945, 10955, and 10970 Alexandria Way, 10996 Torreyana Road,
and 3545 Cray Court
ARE Torrey Ridge
308,565
308,565
3
14,461
86.2
86.2
10578, 10618, and 10628 Science Center Drive
Torrey Pines
1,399,471
1,399,471
13
91,599
94.2
94.2
University Town Center
Megacampus: Campus Point by Alexandria(1)
1,310,696
893,525
2,204,221
8
84,466
99.5
99.5
9880(2), 10210, 10290, and 10300 Campus Point Drive and 4135, 4155, 4224,
and 4242 Campus Point Court
Megacampus: 5200 Illumina Way(1)
792,687
792,687
6
29,978
100.0
100.0
9625 Towne Centre Drive(1)
163,648
163,648
1
6,520
100.0
100.0
University Town Center
2,267,031
893,525
3,160,556
15
120,964
99.7
99.7
Sorrento Mesa
Megacampus: SD Tech by Alexandria(1)
969,416
81,610
1,051,026
11
48,072
98.0
98.0
9605, 9645, 9675, 9725, 9735, 9808, 9855, and 9868 Scranton Road, and
10055, 10065, and 10075 Barnes Canyon Road
Megacampus: Sequence District by Alexandria
671,039
671,039
6
24,306
100.0
100.0
6290, 6310, 6340, 6350, 6420, and 6450 Sequence Drive
Summers Ridge Science Park(1)
316,531
316,531
4
11,521
100.0
100.0
9965, 9975, 9985, and 9995 Summers Ridge Road
10102 Hoyt Park Drive
144,113
144,113
1
11,379
100.0
100.0
5810/5820 Nancy Ridge Drive
83,354
83,354
1
3,389
100.0
100.0
9877 Waples Street
63,774
63,774
1
2,680
100.0
100.0
Sorrento Mesa
2,248,227
81,610
2,329,837
24
101,347
99.1
99.1
Sorrento Valley
3911, 3931, 3985, 4025, 4031, and 4045 Sorrento Valley Boulevard
151,406
151,406
6
4,857
55.9
55.9
11045 Roselle Street
27,689
27,689
1
1,814
100.0
100.0
Sorrento Valley
179,095
179,095
7
6,671
62.7
62.7
San Diego
6,093,824
975,135
7,068,959
59
$320,581
97.2%
97.2%
Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” and “Definitions and reconciliations” in the Supplemental Information for additional details.
(1)We own a partial interest in this property through a real estate joint venture. Refer to “Joint venture financial information” in the Supplemental Information for additional details.
(2)We own 100% of this property.
Property Listing (continued)
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December 31, 2025
(Dollars in thousands)
Market / Submarket / Address
RSF
Number of
Properties
Annual
Rental
Revenue
Occupancy Percentage
Operating
Operating and
Redevelopment
Operating
Development
Redevelopment
Total
Seattle
Lake Union
Megacampus: Alexandria Center® for Life Science – Eastlake
1,151,975
1,151,975
9
$68,694
91.3%
91.3%
1150, 1201(1), 1208(1), 1551, 1600, and 1616 Eastlake Avenue East, 188 and
199 East Blaine Street, and 1600 Fairview Avenue East
Megacampus: Alexandria Center® for Advanced Technologies – South
Lake Union
413,178
227,577
640,755
4
23,372
98.8
98.8
400(1) and 701 Dexter Avenue North, 428 Westlake Avenue North, and 219
Terry Avenue North
Lake Union
1,565,153
227,577
1,792,730
13
92,066
93.3
93.3
Elliott Bay
410 West Harrison Street and 410 Elliott Avenue West
20,101
20,101
2
459
72.5
72.5
Bothell
Megacampus: Alexandria Center® for Advanced Technologies – Canyon
Park
815,000
815,000
19
15,674
84.2
84.2
22121 and 22125 17th Avenue Southeast, 22021, 22025, 22026, 22030,
22118, and 22122 20th Avenue Southeast, 22333, 22422, 22515, and
22522 29th Drive Southeast, 22213 and 22309 30th Drive Southeast, and
1629, 1631, 1725, 1916, and 1930 220th Street Southeast
Alexandria Center® for Advanced Technologies – Monte Villa Parkway
463,243
463,243
6
12,834
79.7
79.7
3301, 3303, 3305, 3307, 3555, and 3755 Monte Villa Parkway
Bothell
1,278,243
1,278,243
25
28,508
82.6
82.6
Other
63,057
63,057
2
481
91.7
91.7
Seattle
2,926,554
227,577
3,154,131
42
121,514
88.4
88.4
Maryland
Rockville
Megacampus: Alexandria Center® for Life Science – Shady Grove
1,691,960
1,691,960
20
93,315
94.7
94.7
9601, 9603, 9605, 9704, 9708, 9712, 9714, 9800, 9804, 9808, 9900, and 9950
Medical Center Drive, 14920 and 15010 Broschart Road, 9920 Belward
Campus Drive, and 9810 and 9820 Darnestown Road
1330 Piccard Drive
131,507
131,507
1
3,813
87.6
87.6
1405 Research Boulevard
72,170
72,170
1
2,501
94.7
94.7
1500 and 1550 East Gude Drive
91,359
91,359
2
1,844
100.0
100.0
5 Research Place
63,852
63,852
1
3,125
100.0
100.0
5 Research Court
51,520
51,520
1
1,976
100.0
100.0
12301 Parklawn Drive
49,185
49,185
1
1,853
100.0
100.0
Rockville
2,151,553
2,151,553
27
$108,427
94.9%
94.9%
Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” and “Definitions and reconciliations” in the Supplemental Information for additional details.
(1)We own a partial interest in this property through a real estate joint venture. Refer to “Joint venture financial information” in the Supplemental Information for additional details.
Property Listing (continued)
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December 31, 2025
(Dollars in thousands)
Market / Submarket / Address
RSF
Number of
Properties
Annual
Rental
Revenue
Occupancy Percentage
Operating
Operating and
Redevelopment
Operating
Development
Redevelopment
Total
Maryland (continued)
Gaithersburg
Alexandria Technology Center® – Gaithersburg I
619,061
619,061
9
$19,663
93.6%
93.6%
9, 25, 35, 45, 50, and 55 West Watkins Mill Road and 910, 930, and 940
Clopper Road
Alexandria Technology Center® – Gaithersburg II
486,300
486,300
7
16,254
95.1
95.1
700, 704, and 708 Quince Orchard Road and 19, 20, 21, and 22 Firstfield
Road
401 Professional Drive
63,207
63,207
1
1,351
79.7
79.7
950 Wind River Lane
50,000
50,000
1
1,234
100.0
100.0
620 Professional Drive
27,950
27,950
1
1,207
100.0
100.0
Gaithersburg
1,246,518
1,246,518
19
39,709
93.9
93.9
Beltsville
8000/9000/10000 Virginia Manor Road
191,884
191,884
1
3,307
96.4
96.4
101 West Dickman Street(1)
142,933
142,933
1
1,726
66.5
66.5
Beltsville
334,817
334,817
2
5,033
83.6
83.6
Maryland
3,732,888
3,732,888
48
153,169
93.6
93.6
Research Triangle
Research Triangle
Megacampus: Alexandria Center® for Life Science – Durham
2,041,067
2,041,067
15
44,493
97.3
97.3
6, 8, 10, 12, 14, 40, 41, 42, and 65 Moore Drive, 21, 25, 27, 29, and 31
Alexandria Way, and 2400 Ellis Road
Megacampus: Alexandria Center® for Advanced Technologies and AgTech
– Research Triangle
711,886
711,886
6
29,585
94.1
94.1
6, 8, 10, and 12 Davis Drive and 5 and 9 Laboratory Drive
Megacampus: Alexandria Center® for Sustainable Technologies
259,962
259,962
6
7,343
84.8
84.8
104, 108, 110, 112, and 114 TW Alexander Drive and 5 Triangle Drive
Alexandria Technology Center® – Alston
121,204
121,204
2
2,279
80.5
80.5
800 and 801 Capitola Drive
Alexandria Innovation Center® – Research Triangle
136,563
136,563
3
4,064
96.1
96.1
7010, 7020, and 7030 Kit Creek Road
2525 East NC Highway 54
82,996
82,996
1
3,580
100.0
100.0
407 Davis Drive
81,956
81,956
1
3,323
100.0
100.0
Research Triangle
3,435,634
3,435,634
34
$94,667
95.2%
95.2%
Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” and “Definitions and reconciliations” in the Supplemental Information for additional details.
(1)We own a partial interest in this property through a real estate joint venture. Refer to “Joint venture financial information” in the Supplemental Information for additional details.
Property Listing (continued)
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December 31, 2025
(Dollars in thousands)
 
Market / Submarket / Address
RSF
Number of
Properties
Annual
Rental
Revenue
Occupancy Percentage
Operating
Operating and
Redevelopment
Operating
Development
Redevelopment
Total
New York City
New York City
Megacampus: Alexandria Center® for Life Science – New York City
729,461
729,461
2
$66,085
96.4%
96.4%
430 and 450 East 29th Street
New York City
729,461
729,461
2
66,085
96.4
96.4
Texas
Austin
Megacampus: Intersection Campus
1,525,359
1,525,359
12
33,694
83.0
83.0
507 East Howard Lane, 13011 McCallen Pass, 13813 and 13929 Center Lake
Drive, and 12535, 12545, 12555, and 12565 Riata Vista Circle
Austin
1,525,359
1,525,359
12
33,694
83.0
83.0
Greater Houston
Alexandria Center® for Advanced Technologies at The Woodlands
120,828
73,298
194,126
1
3,172
41.5
25.8
8800 Technology Forest Place
Texas
1,646,187
73,298
1,719,485
13
36,866
79.9
76.5
Non-cluster/other markets
414,216
414,216
7
12,379
91.2
91.2
North America, excluding properties held for sale
34,330,841
1,998,915
1,564,239
37,893,995
320
1,862,056
90.9%
86.9%
Properties held for sale
1,555,377
1,555,377
20
37,697
66.5%
66.5%
Total North America
35,886,218
1,998,915
1,564,239
39,449,372
340
$1,899,753
Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” and “Definitions and reconciliations” in the Supplemental Information for additional details.
Investments in Real Estate
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December 31, 2025
pipelinepagev2.jpg
ALEXANDRIA’S DEVELOPMENT AND REDEVELOPMENT
DELIVERIES ARE EXPECTED TO PROVIDE INCREMENTAL
GROWTH IN ANNUAL NET OPERATING INCOME
Placed Into
Service
Near-Term
Deliveries
Intermediate-
Term Deliveries
Evaluating
Business
Strategy
2025
2026
20272028
2026-2028
$78M
$97M
$123M
$113M
97%
Occupied
86%
Leased/Negotiating
51%
Leased/Negotiating
8%
Leased/Negotiating
852,764 RSF
699,933 RSF
1.6 million RSF
1.2 million RSF
(1)
(2)
(3)
(4)
(5)
Refer to “Net operating income” under “Definitions and reconciliations” in the Supplemental Information for additional details, including its reconciliation from the most directly comparable financial measure presented in accordance with GAAP.
(1)Excludes future incremental annual net operating income from recently delivered spaces aggregating 20,444 RSF that were vacant and/or unleased at delivery.
(2)Includes expected partial deliveries through 2026 from projects expected to stabilize in 2027-2028, including speculative future leasing that is not yet fully committed. Our share of incremental annual net operating income from projects
expected to be placed into service primarily commencing through 2026 is projected to be $74 million. Refer to the initial and stabilized occupancy years under “New Class A/A+ development and redevelopment properties: current
projects” in the Supplemental Information for additional details.
(3)Our share of incremental annual net operating income from projects expected to stabilize in 2027-2028 is projected to be $92 million.
(4)Represents the current leased/negotiating percentage of development and redevelopment projects that are expected to stabilize through 2026.
(5)Represents the RSF related to projects expected to stabilize in 2026. Does not include RSF for partial deliveries through 2026 from projects expected to stabilize in 2027-2028.
Investments in Real Estate
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December 31, 2025
(Dollars in thousands)
Development and Redevelopment
Under Construction
Operating
2026
Stabilization
2027- 2028
Stabilization
Evaluating
Strategy
Future
Subtotal
Total
Square footage
Operating
34,330,841
34,330,841
Future Class A/A+ development and redevelopment properties
699,933
1,614,994
1,248,227
19,907,130
23,470,284
23,470,284
Future development and redevelopment square feet currently included in
rental properties(1)
(52,620)
(1,815,084)
(1,867,704)
(1,867,704)
Total square footage, excluding properties held for sale
34,330,841
699,933
1,562,374
1,248,227
18,092,046
21,602,580
55,933,421
Properties held for sale
1,555,377
1,893,281
1,893,281
3,448,658
Total square footage
35,886,218
699,933
1,562,374
1,248,227
19,985,327
23,495,861
59,382,079
Investments in real estate
Gross book value as of December 31, 2025(2)
$27,767,849
$777,861
$1,382,807
$1,020,344
$3,868,660
$7,049,672
(3)
$34,817,521
Properties held for sale
452,825
261,208
261,208
714,033
Total gross investment in real estate, excluding properties held for sale
$27,315,024
$777,861
$1,382,807
$1,020,344
$3,607,452
$6,788,464
$34,103,488
chart-305043ce50344fef8dda.gif
20%
17%
11% to 16%
Non-Income-Producing Assets(4) as a Percentage of Gross Assets
(1)Refer to “Investments in real estate” under “Definitions and reconciliations” in the Supplemental Information for additional details, including future development and redevelopment square feet currently included in rental properties.
(2)Balances exclude accumulated depreciation and our share of the cost basis associated with our properties held by our unconsolidated real estate joint ventures, which is classified as investments in unconsolidated real estate joint
ventures in our consolidated balance sheet. Refer to “Investments in real estate” under “Definitions and reconciliations” in the Supplemental Information for additional details.
(3)Our share of investment in our development and redevelopment pipeline is $6.35 billion.
(4)Excludes properties classified as held for sale, of which land parcels represent approximately 1% of total non-income producing assets.
New Class A/A+ Development and Redevelopment Properties: Recent Deliveries
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December 31, 2025
99 Coolidge Avenue
500 North Beacon Street and
4 Kingsbury Avenue(1)
Greater Boston/
Cambridge/Inner Suburbs
Greater Boston/
Cambridge/Inner Suburbs
129,413 RSF
248,018 RSF
100% Occupancy
92% Occupancy
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230 Harriet Tubman Way
10935, 10945, and 10955
Alexandria Way(2)
10075 Barnes Canyon Road
San Francisco Bay Area/
South San Francisco
San Diego/Torrey Pines
San Diego/Sorrento Mesa
285,346 RSF
334,996 RSF
171,469 RSF
100% Occupancy
100% Occupancy
100% Occupancy
harriettubmanv2.jpg
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(1)Image represents 500 North Beacon Street on The Arsenal on the Charles Megacampus.
(2)Image represents 10955 Alexandria Way on the One Alexandria Square Megacampus.
New Class A/A+ Development and Redevelopment Properties: Recent Deliveries
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December 31, 2025
(Dollars in thousands)
Incremental Annual Net Operating Income Generated From 2025 Deliveries
Aggregated $78 Million(1), Including $10 Million in 4Q25
Property/Market/Submarket
Our
Ownership
Interest
RSF Placed in Service
Occupancy
Percentage(3)
Total Project
Unlevered Yields
4Q25
Delivery
Date(2)
Prior to
1/1/25
1Q25
2Q25
3Q25
4Q25
Total
Initial
Stabilized
Initial
Stabilized
(Cash Basis)
RSF
Investment
Development projects
99 Coolidge Avenue/Greater Boston/
Cambridge/Inner Suburbs
N/A
100%
116,414
12,999
129,413
100%
320,809
$444,000
6.0%
6.8%
500 North Beacon Street and 4 Kingsbury
Avenue/Greater Boston/Cambridge/Inner
Suburbs
N/A
100%
211,574
36,444
248,018
92%
248,018
429,000
6.5
5.9
230 Harriet Tubman Way/San Francisco
Bay Area/South San Francisco
N/A
48.6%
285,346
285,346
100%
285,346
476,000
7.5
6.2
10935, 10945, and 10955 Alexandria Way/
San Diego/Torrey Pines
N/A
100%
93,492
119,202
122,302
334,996
100%
334,996
480,000
7.2
6.9
10075 Barnes Canyon Road/San Diego/
Sorrento Mesa
12/18/25
50.0%
17,718
13,772
139,979
171,469
100%
253,079
321,000
5.5
5.7
Weighted average/total
12/18/25
421,480
303,064
119,202
185,517
139,979
1,169,242
1,442,248
$2,150,000
6.6%
6.3%
Assets sold in 2025 or designated as held for sale in 4Q25:
651 Gateway Boulevard/San Francisco Bay
Area/South San Francisco(4)
N/A
N/A
67,017
22,005
89,022
N/A
Canada(5)
N/A
N/A
78,487
6,430
76,567
161,484
N/A
Refer to “New Class A/A+ development and redevelopment properties: current projects” in the Supplemental Information for additional details on the square footage in service and under construction, if applicable.
(1)Excludes future incremental annual net operating income from recently delivered spaces aggregating 20,444 RSF that were vacant and/or unleased at delivery.
(2)Represents the average delivery date for deliveries that occurred during the current quarter, weighted by annual rental revenue.
(3)Occupancy reflects total operating RSF placed in service as of each respective delivery date when the space was placed into service. Subsequent occupancy changes are not reflected.
(4)During December 2025, we sold our 50% controlling interest in a consolidated real estate joint venture at 651 Gateway Boulevard. Refer to “2025 Dispositions and sales of partial interests” in the Earnings Press Release for additional
details.
(5)As of December 31, 2025, our Canada project was designated as held for sale.
New Class A/A+ Development and Redevelopment Properties: Current Projects
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December 31, 2025
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REDUCED FUTURE CONSTRUCTION COMMITMENTS
BY MORE THAN $300 MILLION
FROM FOUR PROJECTS
Submarket
As of 3Q25
Property
CIP RSF
Total Project
Leased/
Negotiating
Project Status
as of 4Q25
Projects under construction as of 3Q25
4,239,762
43%
Redevelopment projects removed from pipeline in 4Q25:
651 Gateway Boulevard
South San Francisco
(237,684)
21%
Sold in 4Q25
Canada
Canada
(56,314)
78
Held for sale as of 4Q25
One Hampshire Street
Cambridge
(104,956)
Held for sale as of 4Q25
401 Park Drive
Fenway
(137,675)
Reclassified to operating(1)
(536,629)
32
Projects placed into service in 4Q25
(139,979)
100
Projects under construction as of 4Q25
3,563,154
46%
(1)We plan to lease this property as office which will require less incremental capital.
New Class A/A+ Development and Redevelopment Properties: Current Projects (continued)
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December 31, 2025
99 Coolidge Avenue
311 Arsenal Street
50 and 60 Sylvan Road(1)
1450 Owens Street
Greater Boston/
Cambridge/Inner Suburbs
Greater Boston/
Cambridge/Inner Suburbs
Greater Boston/Route 128
San Francisco Bay Area/
Mission Bay
191,396 RSF
333,758 RSF
267,015 RSF
212,796 RSF
81% Leased/Negotiating
7% Leased/Negotiating
74% Leased/Negotiating
49% Leased/Negotiating
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269 East Grand Avenue
4135 Campus Point Court
Campus Point by Alexandria
10075 Barnes Canyon Road
701 Dexter Avenue North
San Francisco Bay Area/
South San Francisco
San Diego/
University Town Center
San Diego/
University Town Center
San Diego/Sorrento Mesa
Seattle/Lake Union
107,250 RSF
426,927 RSF
466,598 RSF
81,610 RSF
227,577 RSF
—% Leased/Negotiating
100% Leased
100% Leased
68% Leased/Negotiating
23% Leased/Negotiating
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(1)Image represents 60 Sylvan Road on the Alexandria Center® for Life Science – Waltham Megacampus. The project is expected to capture demand in our Route 128 submarket.
New Class A/A+ Development and Redevelopment Properties: Current Projects (continued)
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December 31, 2025
 
Property/Market/Submarket
Located
on Mega-
campus
Dev/
Redev
Square Footage
Percentage
Occupancy(1)
In Service
CIP
Total
Leased
Leased/
Negotiating
Initial
Stabilized
Under construction
2026 stabilization
99 Coolidge Avenue/Greater Boston/Cambridge/Inner Suburbs
X
Dev
129,413
191,396
320,809
81%
81%
4Q23
4Q26
4135 Campus Point Court/San Diego/University Town Center
X
Dev
426,927
426,927
100
100
3Q26
3Q26
10075 Barnes Canyon Road/San Diego/Sorrento Mesa
X
Dev
171,469
81,610
253,079
68
68
1Q25
2H26
300,882
699,933
1,000,815
86
86
2027-2028 stabilization
311 Arsenal Street/Greater Boston/Cambridge/Inner Suburbs
X
Redev
56,904
333,758
390,662
7
7
2027
2027
50 and 60 Sylvan Road/Greater Boston/Route 128
X
Redev
267,015
267,015
74
74
4Q26
2027
1450 Owens Street/San Francisco Bay Area/Mission Bay
X
Dev
212,796
212,796
49
2027
2027
269 East Grand Avenue/San Francisco Bay Area/South San Francisco
X
Redev
107,250
107,250
2H26
2027
Campus Point by Alexandria/San Diego/University Town Center(2)
X
Dev
466,598
466,598
100
100
2028
2028
701 Dexter Avenue North/Seattle/Lake Union
X
Dev
227,577
227,577
23
23
4Q26
2027
56,904
1,614,994
1,671,898
45
51
Evaluating business strategy
8800 Technology Forest Place/Texas/Greater Houston
Redev
50,094
73,298
123,392
46
46
2Q23
4Q26
3000 Minuteman Road/Greater Boston/Other
X
Redev
453,869
453,869
2027
2027
40 Sylvan Road/Greater Boston/Route 128
X
Redev
329,049
329,049
2027
2027
421 Park Drive/Greater Boston/Fenway
X
Dev
392,011
392,011
13
13
2027
2028
50,094
1,248,227
1,298,321
8
8
Total under construction
407,880
3,563,154
3,971,034
43%
46%
(1)Initial occupancy dates are subject to leasing and/or market conditions. Stabilized occupancy may vary depending on single tenancy versus multi-tenancy. Multi-tenant projects may increase in occupancy over time.
(2)Represents a single-tenant project that expands the existing Campus Point by Alexandria Megacampus, where we currently have a 56.4% interest. The project is fully leased to a longtime multinational pharmaceutical tenant that currently
occupies two buildings within the Megacampus: one building aggregating 52,620 RSF and another building aggregating 52,853 RSF. These buildings generated annual rental revenue of $7.5 million as of 4Q25. At the beginning of 2026, the
tenant will vacate the 52,620 RSF building, and during 2028, the tenant will vacate the 52,853 RSF building. We expect to fund the majority of future construction costs at the Megacampus until our ownership interest increases to 75%, after
which future capital would be contributed pro rata with our joint venture partner.
New Class A/A+ Development and Redevelopment Properties: Current Projects (continued)
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December 31, 2025
(Dollars in thousands)
Our
Ownership
Interest
At 100%
Unlevered Yields
Property/Market/Submarket
In Service
CIP
Cost to
Complete
Total at
Completion
Initial
Stabilized
Initial Stabilized
(Cash Basis)
Under construction
2026 stabilization with 86% leased/negotiating
99 Coolidge Avenue/Greater Boston/Cambridge/Inner Suburbs
100%
$162,887
$210,603
$70,510
$444,000
6.0%
6.8%
4135 Campus Point Court/San Diego/University Town Center
56.4%
434,465
89,535
524,000
9.4%
6.2%
10075 Barnes Canyon Road/San Diego/Sorrento Mesa
50.0%
123,133
132,793
65,074
321,000
5.5%
5.7%
286,020
777,861
2027-2028 stabilization with 51% leased/negotiating(1)
311 Arsenal Street/Greater Boston/Cambridge/Inner Suburbs
100%
21,854
306,028
TBD
50 and 60 Sylvan Road/Greater Boston/Route 128
100%
345,046
1450 Owens Street/San Francisco Bay Area/Mission Bay
25.0%
247,271
269 East Grand Avenue/San Francisco Bay Area/South San Francisco
100%
119,546
Campus Point by Alexandria/San Diego/University Town Center(2)
56.4%
62,790
597,210
660,000
7.3%
6.5%
701 Dexter Avenue North/Seattle/Lake Union
100%
302,126
TBD
21,854
1,382,807
Evaluating business strategy with 8% leased/negotiating
8800 Technology Forest Place/Texas/Greater Houston
100%
60,938
46,578
4,484
112,000
6.3%
6.0%
3000 Minuteman Road/Greater Boston/Other
100%
163,966
TBD
40 Sylvan Road/Greater Boston/Route 128
100%
225,791
421 Park Drive/Greater Boston/Fenway
100%
584,009
60,938
1,020,344
Total under construction
$368,812
$3,181,012
$2,110,000
(3)
$5,660,000
(3)
Our share of investment(3)(4)
$310,000
$2,710,000
$1,710,000
$4,730,000
Refer to “Initial stabilized yield (unlevered)” under “Definitions and reconciliations” in the Supplemental Information for additional details.
(1)We expect to provide total estimated costs and related yields for each project over the next several quarters.
(2)Refer to footnote 2 on the prior page for additional details.
(3)Represents dollar amount rounded to the nearest $10 million and includes preliminary estimated amounts for projects listed as TBD.
(4)Represents our share of investment based on our current ownership percentage upon completion of development or redevelopment projects. Our share of investment will be adjusted as our ownership percentage increases at the Campus
Point project.
New Class A/A+ Development and Redevelopment Properties: Summary of Pipeline
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December 31, 2025
(Dollars in thousands)
77% of Our Total Development and Redevelopment Pipeline RSF
Is Within Our Megacampus Ecosystems
Market
Property/Submarket
Our
Ownership
Interest
Book Value
Square Footage
Development and Redevelopment
Under
Construction
Future
Total(1)
Greater Boston
Megacampus: The Arsenal on the Charles/Cambridge/Inner Suburbs
100%
$318,404
333,758
34,157
367,915
311 Arsenal Street
Megacampus: 480 Arsenal Way and 446, 458, and 500 Arsenal Street, and 99 Coolidge Avenue/
Cambridge/Inner Suburbs
100%
234,388
191,396
560,000
751,396
446, 458, and 500 Arsenal Street, and 99 Coolidge Avenue
Megacampus: Alexandria Center® for Life Science – Fenway/Fenway
100%
584,009
392,011
392,011
421 Park Drive
Megacampus: Alexandria Center® for Life Science – Waltham/Route 128
100%
635,997
596,064
515,000
1,111,064
40, 50, and 60 Sylvan Road, and 35 Gatehouse Drive
Megacampus: 30, 200, and 3000 Minuteman Road/Other
100%
222,659
453,869
608,541
1,062,410
3000 Minuteman Road
Megacampus: Alexandria Technology Square®/Cambridge
100%
8,631
100,000
100,000
10 Necco Street/Seaport Innovation District
100%
107,099
175,000
175,000
215 Presidential Way/Route 128
100%
6,816
112,000
112,000
Other development and redevelopment projects
100%
162,935
740,000
740,000
$2,280,938
1,967,098
2,844,698
4,811,796
Refer to “Megacampus™” under “Definitions and reconciliations” in the Supplemental Information for additional details.
(1)Represents total square footage upon completion of development or redevelopment of one or more new Class A/A+ properties. Square footage presented includes the RSF of buildings currently in operation at properties that also have
future development or redevelopment opportunities. Upon expiration of existing in-place leases, we have the intent to demolish or redevelop the existing property subject to market conditions and leasing. Refer to “Investments in real
estate” under “Definitions and reconciliations” in the Supplemental Information for additional details, including development and redevelopment square feet currently included in rental properties.
New Class A/A+ Development and Redevelopment Properties: Summary of Pipeline (continued)
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December 31, 2025
(Dollars in thousands)
Market
Property/Submarket
Our
Ownership
Interest
Book Value
Square Footage
Development and Redevelopment
Under
Construction
Future
Total(1)
San Francisco Bay Area
Megacampus: Alexandria Center® for Science and Technology – Mission Bay/Mission Bay
25.0%
$247,271
212,796
212,796
1450 Owens Street
Megacampus: Alexandria Center® for Advanced Technologies – South San Francisco/South San
Francisco
100%
126,201
107,250
90,000
197,250
211(2) and 269 East Grand Avenue
Megacampus: Alexandria Center® for Advanced Technologies – Tanforan/South San Francisco
100%
436,956
1,930,000
1,930,000
1122, 1150, and 1178 El Camino Real
Alexandria Center® for Life Science – Millbrae/South San Francisco
48.6%
160,822
348,401
348,401
201 and 231 Adrian Road and 30 Rollins Road
Megacampus: Alexandria Center® for Life Science – San Carlos/Greater Stanford
100%
486,468
1,497,830
1,497,830
960 Industrial Road, 987 and 1075 Commercial Street, and 888 Bransten Road
2100, 2200, 2300, and 2400 Geng Road/Greater Stanford
100%
83,082
240,000
240,000
1,540,800
320,046
4,106,231
4,426,277
San Diego
Megacampus: Campus Point by Alexandria/University Town Center
56.4%
(3)
643,229
893,525
500,859
1,394,384
10010(4), 10140(4), 10210, and 10260 Campus Point Drive and 4135, 4161, 4165, and 4224 Campus Point
Court
Megacampus: SD Tech by Alexandria/Sorrento Mesa
50.0%
249,021
81,610
493,845
575,455
9805 Scranton Road and 10075 Barnes Canyon Road
11255 and 11355 North Torrey Pines Road/Torrey Pines
100%
161,539
215,000
215,000
Megacampus: One Alexandria Square/Torrey Pines
100%
65,706
125,280
125,280
10975 and 10995 Torreyana Road
Megacampus: 5200 Illumina Way/University Town Center
51.0%
17,982
451,832
451,832
9625 Towne Centre Drive/University Town Center
30.0%
837
100,000
100,000
Megacampus: Sequence District by Alexandria/Sorrento Mesa
100%
48,992
1,661,915
1,661,915
6290, 6310, 6340, 6350, and 6450 Sequence Drive
4075 Sorrento Valley Boulevard/Sorrento Valley
100%
29,224
144,000
144,000
Other development and redevelopment projects
(2)
78,036
475,000
475,000
$1,294,566
975,135
4,167,731
5,142,866
Refer to “Megacampus™” under “Definitions and reconciliations” in the Supplemental Information for additional details.
(1)Represents total square footage upon completion of development or redevelopment of one or more new Class A/A+ properties. Square footage presented includes the RSF of buildings currently in operation at properties that also have
future development or redevelopment opportunities. Upon expiration of existing in-place leases, we have the intent to demolish or redevelop the existing property subject to market conditions and leasing. Refer to “Investments in real
estate” under “Definitions and reconciliations” in the Supplemental Information for additional details, including development and redevelopment square feet currently included in rental properties.
(2)Includes a property in which we own a partial interest through a real estate joint venture. Refer to “Joint venture financial information” in the Supplemental Information for additional details.
(3)The noncontrolling interest share of our real estate joint venture partner is anticipated to decrease to 25%, as we expect to fund the majority of future construction costs at the campus until our ownership interest increases to 75%, after
which future capital would be contributed pro rata with our partner.
(4)We have a 100% interest in this property.
New Class A/A+ Development and Redevelopment Properties: Summary of Pipeline (continued)
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December 31, 2025
(Dollars in thousands)
Market
Property/Submarket
Our
Ownership
Interest
Book Value
Square Footage
Development and Redevelopment
Under
Construction
Future
Total(1)
Seattle
Megacampus: Alexandria Center® for Advanced Technologies – South Lake Union/Lake Union
(2)
$596,213
227,577
1,057,400
1,284,977
601 and 701 Dexter Avenue North and 800 Mercer Street
1010 4th Avenue South/SoDo
100%
62,763
544,825
544,825
410 West Harrison Street/Elliott Bay
100%
91,000
91,000
Megacampus: Alexandria Center® for Advanced Technologies – Canyon Park/Bothell
100%
20,256
230,000
230,000
21660 20th Avenue Southeast
Other development and redevelopment projects
100%
155,787
706,087
706,087
835,019
227,577
2,629,312
2,856,889
Maryland
Megacampus: Alexandria Center® for Life Science – Shady Grove/Rockville
100%
28,382
296,000
296,000
9830 Darnestown Road
28,382
296,000
296,000
Research Triangle
Megacampus: Alexandria Center® for Life Science – Durham/Research Triangle
100%
165,816
2,060,000
2,060,000
Megacampus: Alexandria Center® for Advanced Technologies and AgTech – Research Triangle/
Research Triangle
100%
113,493
1,170,000
1,170,000
4 and 12 Davis Drive
Megacampus: Alexandria Center® for Sustainable Technologies/Research Triangle
100%
56,351
750,000
750,000
120 TW Alexander Drive, 2752 East NC Highway 54, and 10 South Triangle Drive
Other development and redevelopment projects
100%
1,647
25,000
25,000
337,307
4,005,000
4,005,000
New York City
Megacampus: Alexandria Center® for Life Science – New York City/New York City
100%
178,148
550,000
(3)
550,000
$178,148
550,000
550,000
Refer to “Megacampus™” under “Definitions and reconciliations” in the Supplemental Information for additional details.
(1)Represents total square footage upon completion of development or redevelopment of one or more new Class A/A+ properties. Square footage presented includes the RSF of buildings currently in operation at properties that also have
future development or redevelopment opportunities. Upon expiration of existing in-place leases, we have the intent to demolish or redevelop the existing property subject to market conditions and leasing. Refer to “Investments in real
estate” under “Definitions and reconciliations” in the Supplemental Information for additional details, including development and redevelopment square feet currently included in rental properties.
(2)We have a 100% interest in 601 and 701 Dexter Avenue North aggregating 415,977 RSF and a 60% interest in the future development project at 800 Mercer Street aggregating 869,000 RSF.
(3)During the three months ended September 30, 2024, we filed a lawsuit against the New York City Health + Hospitals Corporation and the New York City Economic Development Corporation for fraud and breach of contract concerning our
option to ground lease a land parcel to develop a future world-class life science building within the Alexandria Center® for Life Science – New York City Megacampus. Refer to our annual report on Form 10-K for the three months ended
December 31, 2025 filed with the SEC on January 26, 2026 for additional details.
New Class A/A+ Development and Redevelopment Properties: Summary of Pipeline (continued)
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December 31, 2025
(Dollars in thousands)
Market
Property/Submarket
Our
Ownership
Interest
Book Value
Square Footage
Development and Redevelopment
Under
Construction
Future
Total(1)
Texas
Alexandria Center® for Advanced Technologies at The Woodlands/Greater Houston
100%
$49,691
73,298
116,405
189,703
8800 Technology Forest Place
1001 Trinity Street and 1020 Red River Street/Austin
100%
135,868
250,010
250,010
Other development and redevelopment projects
100%
60,241
344,000
344,000
245,800
73,298
710,415
783,713
Other development and redevelopment projects
100%
47,504
597,743
597,743
Total pipeline as of December 31, 2025, excluding properties held for sale
6,788,464
3,563,154
19,907,130
23,470,284
Properties held for sale
261,208
1,893,281
1,893,281
Total pipeline as of December 31, 2025
$7,049,672
(2)
3,563,154
21,800,411
25,363,565
Refer to “Megacampus™” under “Definitions and reconciliations” in the Supplemental Information for additional details.
(1)Total square footage includes 1.9 million RSF of buildings currently in operation that we expect to demolish or redevelop and commence future construction subject to market conditions and leasing. Refer to “Investments in real estate
under “Definitions and reconciliations” in the Supplemental Information for additional details, including development and redevelopment square feet currently included in rental properties.
(2)Includes $3.18 billion of projects that are currently under construction.
Construction Spending
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December 31, 2025
(Dollars in thousands)
Construction spending
Projected Guidance
Midpoint for Year Ending
December 31, 2026
Year Ended
December 31, 2025
Year Ended
December 31, 2024
Construction of Class A/A+ properties:
Active construction projects
Includes development and redevelopment under construction(1)
$
1,445,000
$
1,216,572
$
1,791,097
Future pipeline pre-construction
Primarily Megacampus expansion pre-construction work (entitlement, design, and site work)
210,000
(2)
275,971
426,948
Revenue- and non-revenue-enhancing capital expenditures(3)
510,000
(4)
324,293
273,377
Construction spending (before contributions from noncontrolling interests or tenants)
2,165,000
1,816,836
2,491,422
Contributions from noncontrolling interests (consolidated real estate joint ventures)
(100,000)
(5)
(193,936)
(343,798)
Tenant-funded and -built landlord improvements
(315,000)
(178,651)
(129,152)
Total construction spending
$
1,750,000
$
1,444,249
$
2,018,472
2026 guidance range for construction spending
$1,500,000 – $2,000,000
Projected capital contributions from partners in consolidated real estate joint ventures to fund construction
Timing
Amount(5)
2026
$100,000
2027 and beyond
37,000
Total
$137,000
Refer to “Definitions and reconciliations” in the Supplemental Information for additional details.
(1)Includes smaller conversions to laboratory space through redevelopment.
(2)Approximately 75% represents capitalized costs.
(3)Represents revenue- and non-revenue-enhancing capital expenditures before contributions from noncontrolling interests and tenant-funded and tenant-built landlord improvements.
(4)The top two revenue- and non-revenue-enhancing capital expenditure projects in 2026 represent approximately 55% of the total spending within this category. The first project relates to a property located at the Alexandria Center® for
Advanced Technologies – South San Francisco Megacampus in our South San Francisco submarket, which is leased to a new tenant and is undergoing its first major renovation in 12 years. The second project relates to a property at the
Alexandria Technology Square® Megacampus in our Cambridge submarket, which is undergoing its first major renovation in 16 years.
(5)Represents contractual capital commitments from existing real estate joint venture partners to fund construction.
Capitalization of Interest
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December 31, 2025
(Dollars in thousands)
Leased/
Negotiating
Average Real Estate
Basis Capitalized
During 2025
Percentage of Total
Average Real Estate
Basis Capitalized
Key Categories of Real Estate Basis Capitalized
Construction of Class A/A+ properties:
Development and redevelopment of projects under construction:
2026 stabilization
86%
$590,069
7%
2027-2028 stabilization
51%
1,308,800
16
Evaluating business strategy
8%
878,661
11
Repositioning and smaller redevelopment projects
1,187,460
(1)
15
Future pipeline projects with critical pre-construction milestones during 2026:
Megacampus projects
2,078,801
(2)
25
Non-Megacampus projects
987,518
(2)
12
Assets sold in 2025 or designated as held for sale as of 4Q25(3)
1,115,707
14
Total average real estate basis capitalized(4)
$8,147,016
100%
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Under construction – evaluating business
strategy$878.7 million
Repositioning and smaller redevelopment
projects(1) $1.19 billion
Under construction – 2026 stabilization
$590.1 million (86% leased/negotiating)
Future projects with critical milestones in 2026 – 
Megacampus projects(2) $2.08 billion
Under construction – 2027-2028 stabilization
$1.31 billion (51% leased/negotiating)
Future projects with critical milestones in 2026 –
Non-Megacampus projects $987.5 million
Assets sold in 2025 or designated as
held for sale as of 4Q25 $1.12 billion
Percentage of Total Average Real Estate Basis Capitalized During 2025
(1)Includes the real estate basis related to the 899,259 RSF of vacant space as of December 31, 2025 that is leased with future delivery. The weighted-average expected delivery date is approximately August 2026.
(2)Approximately 74% of future pipeline projects are expected to reach anticipated pre-construction milestones, including various phases of entitlement, design, site work, and other activities necessary to begin aboveground
vertical construction, on a weighted-average real estate investment basis by May 2026. At each milestone date, we will evaluate whether to proceed with additional pre-construction and/or construction activities based on leasing
demand and/or market conditions, pause future investments, or consider the potential dispositions of real estate assets.
(3)The weighted-average date as of which capitalization of interest ceased was in early December 2025.
(4)In addition to capitalized interest, we incur additional capitalized project costs, including property taxes, insurance, payroll, and other costs directly related and essential to the construction of Class A/A+ properties. If we cease
activities necessary to prepare a project for its intended use, costs related to such project are expensed as incurred. Annualized capitalized operating expenses and payroll represent approximately 2% and 1%, respectively, of
the total average real estate basis subject to capitalization for 2025.
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Joint Venture Financial Information
December 31, 2025
Consolidated Real Estate Joint Ventures
Property
Market
Submarket
Noncontrolling
Interest Share(1)
Operating RSF
at 100%
50 and 60 Binney Street
Greater Boston
Cambridge/Inner Suburbs
66.0%
532,395
75/125 Binney Street
Greater Boston
Cambridge/Inner Suburbs
60.0%
388,270
100 and 225 Binney Street and 300 Third Street
Greater Boston
Cambridge/Inner Suburbs
70.0%
870,641
15 Necco Street
Greater Boston
Seaport Innovation District
43.3%
345,996
Alexandria Center® for Science and Technology – Mission Bay(3)
San Francisco Bay Area
Mission Bay
75.0%
548,215
211 and 213 East Grand Avenue
San Francisco Bay Area
South San Francisco
70.0%
300,930
500 Forbes Boulevard
San Francisco Bay Area
South San Francisco
90.0%
155,685
Alexandria Center® for Life Science – Millbrae
San Francisco Bay Area
South San Francisco
51.4%
285,346
3215 Merryfield Row
San Diego
Torrey Pines
70.0%
170,523
Campus Point by Alexandria(2)(4)
San Diego
University Town Center
43.6%
(5)
1,212,414
5200 Illumina Way
San Diego
University Town Center
49.0%
792,687
9625 Towne Centre Drive
San Diego
University Town Center
70.0%
163,648
SD Tech by Alexandria(2)(6)
San Diego
Sorrento Mesa
50.0%
969,416
Summers Ridge Science Park(7)
San Diego
Sorrento Mesa
70.0%
316,531
1201 and 1208 Eastlake Avenue East
Seattle
Lake Union
70.0%
206,134
400 Dexter Avenue North
Seattle
Lake Union
70.0%
290,754
800 Mercer Street
Seattle
Lake Union
40.0%
(2)
Unconsolidated Real Estate Joint Ventures
Property
Market
Submarket
Our Ownership
Share(8)
Operating RSF
at 100%
1655 and 1725 Third Street
San Francisco Bay Area
Mission Bay
10.0%
586,208
101 West Dickman Street
Maryland
Beltsville
58.4%
(9)
142,933
Refer to “Joint venture financial information” under “Definitions and reconciliations” in the Supplemental Information for additional details.
(1)In addition to the real estate joint ventures listed, we have one consolidated real estate joint venture in the Greater Boston market in which a partner holds a $49.6 million redeemable noncontrolling interest earning a fixed return as
of December 31, 2025.
(2)Represents a property currently under construction or in our future development and redevelopment pipeline. Refer to the sections under “New Class A/A+ development and redevelopment properties” in the Supplemental
Information for additional details.
(3)Includes 1450, 1500, and 1700 Owens Street and 455 Mission Bay Boulevard South.
(4)Includes 10210, 10260, 10290, and 10300 Campus Point Drive and 4110, 4135, 4155, 4161, 4165, 4224, and 4242 Campus Point Court.
(5)The noncontrolling interest share of our real estate joint venture partner is anticipated to decrease to 25%, as we expect to fund the majority of future construction costs at the campus until our ownership interest increases to 75%,
after which future capital would be contributed pro rata with our partner. Refer to “New Class A/A+ development and redevelopment properties: current projects” in the Supplemental Information for additional details.
(6)Includes 9605, 9645, 9675, 9725, 9735, 9805, 9808, 9855, and 9868 Scranton Road and 10055, 10065, and 10075 Barnes Canyon Road.
(7)Includes 9965, 9975, 9985, and 9995 Summers Ridge Road.
(8)In addition to the real estate joint ventures listed, we hold an interest in two insignificant unconsolidated real estate joint ventures. 
(9)Represents a joint venture with a local real estate operator in which our joint venture partner manages the day-to-day activities that significantly affect the economic performance of the joint venture.
Joint Venture Financial Information (continued)
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December 31, 2025
(In thousands)
As of December 31, 2025
Noncontrolling Interest
Share of Consolidated
Real Estate JVs
Our Share of
Unconsolidated
Real Estate JVs
Investments in real estate
$
3,317,283
$
83,974
Cash, cash equivalents, and restricted cash
139,397
1,853
Other assets
402,602
10,238
Secured notes payable
(60,864)
Other liabilities
(172,916)
(4,524)
Redeemable noncontrolling interests
(58,788)
$
3,627,578
$
30,677
Noncontrolling Interest Share of
Consolidated Real Estate JVs
Our Share of Unconsolidated
Real Estate JVs
December 31, 2025
December 31, 2025
Three Months Ended
Year Ended
Three Months Ended
Year Ended
Total revenues
$
114,339
$
467,580
$
2,656
$
10,619
Rental operations
(36,231)
(145,209)
(1,040)
(4,048)
78,108
322,371
1,616
6,571
General and administrative
(823)
(3,016)
(32)
(133)
Interest
(62)
(967)
(1,058)
(4,176)
Depreciation and amortization of real estate assets
(39,942)
(154,727)
(855)
(3,703)
Impairment of real estate
(265,266)
(1)
(265,266)
(8,673)
Gain on sale of real estate of consolidated JV
312,807
(2)
312,807
Gain on sale of interest of unconsolidated JV
25
483
Fixed returns allocated to redeemable noncontrolling interests(3)
699
1,642
$
85,521
$
212,844
$
(304)
$
(9,631)
Straight-line rent and below-market lease revenue
$
2,723
$
19,580
$
139
$
645
Funds from operations(4)
$
77,922
$
320,030
$
526
$
2,262
Refer to “Joint venture financial information” under “Definitions and reconciliations” in the Supplemental Information for additional details.
(1)Relates to our partners’ share of impairment charges recognized in connection with real estate properties held by consolidated joint ventures at 601, 611, 651, 681, 685, 701, and 751 Gateway Boulevard and 285, 299, 307, and
345 Dorchester Avenue. Refer to “2025 dispositions and sales of partial interests” in the Earnings Press Release for additional details.
(2)Relates to our partner’s share of the gain on sale of real estate recognized upon the disposition of the properties at 409 and 499 Illinois Street.
(3)Represents an allocation of joint venture earnings to redeemable noncontrolling interests for properties in the Greater Boston and San Francisco Bay Area markets. These redeemable noncontrolling interests earn a fixed return on
their investment rather than participate in the operating results of the properties.
(4)Refer to “Funds from operations and funds from operations per share” in the Earnings Press Release and “Definitions and reconciliations” in the Supplemental Information for additional details.
Investments
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December 31, 2025
(Dollars in thousands)
We hold investments in publicly traded companies and privately held entities primarily involved in the life science industry. The tables below summarize components of our investment income
(loss) and non-real estate investments. Refer to “Investments” under “Definitions and reconciliations” in the Supplemental Information for additional details.
December 31, 2025
Year Ended
December 31, 2024
Three Months Ended
Year Ended
Realized (losses) gains:
Realized gains
$21,072
$115,722
$117,214
Impairment of non-real estate investments
(20,181)
(1)
(95,716)
(58,090)
Significant realized loss
(103,329)
(2)
(103,329)
(2)
(102,438)
(83,323)
59,124
Unrealized gains (losses)
98,548
(3)
26,980
(4)
(112,246)
(5)
Investment loss
$(3,890)
$(56,343)
$(53,122)
December 31, 2025
December 31, 2024
Investments
Cost
Unrealized Gains
Unrealized Losses
Carrying Amount
Carrying Amount
Publicly traded companies
$54,752
$44,319
$(4,143)
$94,928
$105,667
Entities that report NAV
460,160
89,514
(37,298)
512,376
609,866
Entities that do not report NAV:
Entities with observable price changes
82,252
50,601
(9,615)
123,238
174,737
Entities without observable price changes
413,324
413,324
400,487
Investments accounted for under the equity method
  N/A
N/A
N/A
357,383
186,228
December 31, 2025
$1,010,488
(6)
$184,434
$(51,056)
$1,501,249
$1,476,985
December 31, 2024
$1,207,146
$228,100
$(144,489)
$1,476,985
Public/Private Mix (Cost)
Tenant/Non-Tenant Mix (Cost)
chart-1bf2807853bf4ada9dc.gif
chart-c2c07de07bdf4996aba.gif
18%
Tenant
4%
Public
82%
Non-Tenant
96%
Private
(1)Primarily related to two non-real estate investments in privately held entities that do not report NAV.
(2)In November 2025, we contributed certain publicly traded securities to an unconsolidated joint venture, which resulted in a realized loss of $103.3 million on one transaction that was previously reflected as unrealized losses within
investment income in our consolidated statement of operations. The unconsolidated joint venture sold these securities and distributed $39.9 million to us in December 2025.
(3)Consists of unrealized gains of $24.2 million primarily resulting from the increase in fair values of our investments in privately held entities that report NAV and $74.3 million resulting from accounting reclassifications of unrealized losses
recognized in prior periods into realized losses upon our realization of investments during the three months ended December 31, 2025.
(4)Primarily relates to the increase in fair values of our investments in publicly traded entities during the year ended December 31, 2025.
(5)Primarily relates to the accounting reclassifications of unrealized gains recognized in prior periods into realized gains upon our realization of investments during the year ended December 31, 2024.
(6)Represents 2.5% of gross assets as of December 31, 2025. Refer to “Gross assets” under “Definitions and reconciliations” in the Supplemental Information for additional details.
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Balance Sheet
December 31, 2025
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ALEXANDRIA CONTINUES TO HAVE A STRONG AND FLEXIBLE
BALANCE SHEET WITH SIGNIFICANT LIQUIDITY
SIGNIFICANT
LIQUIDITY
PERCENTAGE OF FIXED-RATE
DEBT SINCE 2021(1)
$5.3B
96.7%
REMAINING DEBT TERM
(IN YEARS)
DEBT INTEREST
RATE
12.1
3.91%
Longest Among S&P 500 REITs(3)
ACHIEVED
4Q25 LEVERAGE(2)
5.7x
WEIGHTED AVERAGE
TOP 15%
BBB+
Negative
Baa1
Negative
CREDIT RATING RANKING AMONG
ALL PUBLICLY TRADED U.S. REITS(4)
As of December 31, 2025. Refer to “Definitions and reconciliations” in the Supplemental Information for additional details.
(1)Represents the average quarterly percentage fixed-rate debt as of each quarter-end from January 1, 2021 through December 31, 2025.
(2)Represents net debt and preferred stock to Adjusted EBITDA for the fourth quarter annualized.
(3)Sources: S&P Global Market Intelligence, Bloomberg, or company filings (data not disclosed for SBAC, PSA, and WY) as of September 30, 2025, except for ARE, which is as of December 31, 2025.
(4)Top 15% ranking represents credit rating levels from S&P Global Ratings and Moody’s Ratings for publicly traded U.S. REITs, from Bloomberg Professional Services and Nareit, as of December 31, 2025.
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Key Credit Metrics
December 31, 2025
Liquidity
Limited Outstanding Borrowings and Significant Availability
on Unsecured Senior Line of Credit
(in millions)
$5.3B
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(in millions)
Availability under our unsecured senior line of credit, net of amounts
outstanding under our commercial paper program
$4,647
Cash, cash equivalents, and restricted cash
554
Investments in publicly traded companies
95
Liquidity as of December 31, 2025
$5,296
Net Debt and Preferred Stock to Adjusted EBITDA(1)
Fixed-Charge Coverage Ratio(1)
chart-f25ae6f8704b44f4adf.gif
chart-f823b631995e4c018e1.gif
5.6x to 6.2x
3.6x to 4.1x
Refer to “Definitions and reconciliations” in the Supplemental Information for additional details.
(1)Quarter annualized.
Summary of Debt
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December 31, 2025
(Dollars in millions)
Weighted-Average Remaining Term of 12.1 Years
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(1)In January 2026, we repaid $300.0 million of 4.30% unsecured senior notes payable upon maturity. No gain or loss was incurred in connection with this repayment.
(2)Refer to footnotes 2 through 4 on page 52 under “Fixed-rate and variable-rate debt” for additional details.
Summary of Debt (continued)
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December 31, 2025
ALEXANDRIA HAS THE LONGEST WEIGHTED-AVERAGE REMAINING DEBT TERM
AMONG S&P 500 REITS AT OVER 2X THE AVERAGE DEBT TERM FOR THESE REITS
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debttermbox.jpg
5.9 Years
Average Debt Term
of S&P 500 REITs
as of September 30, 2025
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WEIGHTED-AVERAGE REMAINING DEBT TERM (IN YEARS)
Sources: S&P Global Market Intelligence, Bloomberg, or company filings (data not disclosed for SBAC, PSA, and WY) as of September 30, 2025, except for ARE, which is as of December 31, 2025.
Summary of Debt (continued)
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December 31, 2025
(Dollars in thousands)
Fixed-rate and variable-rate debt
Fixed-Rate
Debt
Variable-Rate
Debt
Total
Percentage
Weighted-Average
Interest Rate(1)
Remaining Term
(in years)
Unsecured senior notes payable
$12,047,394
$
$12,047,394
97.2%
3.90%
12.3
Unsecured senior line of credit(2) and commercial
paper program(3)
353,161
353,161
2.8
4.33
4.1
(4)
Total/weighted average
$12,047,394
$353,161
$12,400,555
100.0%
3.91%
12.1
(4)
Percentage of total debt
97.2%
2.8%
100.0%
(1)Represents the weighted-average interest rate as of the end of the applicable period, including expense/income related to the amortization of loan fees, amortization of debt premiums (discounts), and other bank fees.
(2)As of December 31, 2025, we had no outstanding balance on our unsecured senior line of credit.
(3)The commercial paper program provides us with the ability to issue up to $2.50 billion of commercial paper notes that bear interest at short-term fixed rates and can generally be issued with a maturity of 30 days or less and with
a maximum maturity of 397 days from the date of issuance. Borrowings under the program are used to fund short-term capital needs and are back-stopped by our unsecured senior line of credit. In the event we are unable to
issue commercial paper notes or refinance outstanding borrowings under terms equal to or more favorable than those under our unsecured senior line of credit, we expect to borrow under the unsecured senior line of credit at
SOFR+0.855%. As of December 31, 2025, we had $353.2 million of commercial paper notes outstanding.
(4)We calculate the weighted-average remaining term of our commercial paper notes by using the maturity date of our unsecured senior line of credit. Using the maturity date of our outstanding commercial paper notes, the
consolidated weighted-average maturity of our debt is 12.0 years. The commercial paper notes sold during the year ended December 31, 2025 were issued at a weighted-average yield to maturity of 4.48% and had a weighted-
average maturity term of 19 days.
Average Debt Outstanding
Weighted-Average Interest Rate
December 31, 2025
December 31, 2025
Three Months Ended
Year Ended
Three Months Ended
Year Ended
Long-term fixed-rate debt
$12,121,545
$12,248,039
3.88%
3.87%
Short-term variable-rate unsecured senior line of credit and commercial paper
program debt
2,318,358
1,281,104
4.28
4.55
Blended-average interest rate
14,439,903
13,529,143
3.94
3.93
Loan fee amortization and annual facility fee related to unsecured senior line of credit
N/A
N/A
0.13
0.13
Total/weighted average
$14,439,903
$13,529,143
4.07%
4.06%
Summary of Debt (continued)
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December 31, 2025
(Dollars in thousands)
Debt covenants
Unsecured Senior Notes Payable
Unsecured Senior Line of Credit
Debt Covenant Ratios(1)
Requirement
December 31, 2025
Requirement
December 31, 2025
Total Debt to Total Assets
≤ 60%
32%
≤ 60.0%
33.5%
Secured Debt to Total Assets
≤ 40%
—%
≤ 45.0%
—%
Consolidated EBITDA to Interest Expense
≥ 1.5x
7.8x
≥ 1.50x
3.41x
Unencumbered Total Asset Value to Unsecured Debt
≥ 150%
302%
N/A
N/A
Unsecured Interest Coverage Ratio
N/A
N/A
≥ 1.75x
7.63x
(1)All covenant ratio titles utilize terms as defined in the respective debt and credit agreements. The calculation of consolidated EBITDA is based on the definitions contained in our loan agreements and is not directly comparable to
the computation of EBITDA as described in Exchange Act Release No. 47226.
Unconsolidated real estate joint ventures’ debt
At 100%
Unconsolidated Joint Venture
Maturity Date
Stated Rate
Interest Rate(1)
Aggregate
Commitment
Debt Balance(2)
Our Share
101 West Dickman Street
10/29/26
SOFR+1.95%
(3)
5.74%
$26,750
$19,136
58.4%
1655 and 1725 Third Street
2/10/35
6.37%
6.44%
500,000
496,881
10.0%
$526,750
$516,017
(1)Includes interest expense and amortization of loan fees.
(2)Represents outstanding principal, net of unamortized deferred financing costs, as of December 31, 2025.
(3)This loan is subject to a fixed SOFR floor of 0.75%.
Summary of Debt (continued)
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December 31, 2025
(Dollars in thousands)
Debt
Stated 
Rate
Interest
Rate(1)
Maturity
Date(2)
Principal Payments Remaining for the Periods Ending December 31,
Principal
Unamortized
(Deferred
Financing
Cost),
(Discount)/
Premium
Total
2026
2027
2028
2029
2030
Thereafter
Unsecured senior line of credit and commercial
paper program(3)
(3)
4.33%
(3)
1/22/30
(3)
$
$
$
$
$353,500
$
$353,500
$(339)
$353,161
Unsecured senior notes payable
4.30%
4.50
1/15/26
(4)
300,000
300,000
(36)
299,964
Unsecured senior notes payable
3.80%
3.96
4/15/26
350,000
350,000
(162)
349,838
Unsecured senior notes payable
3.95%
4.13
1/15/27
350,000
350,000
(555)
349,445
Unsecured senior notes payable
3.95%
4.07
1/15/28
425,000
425,000
(888)
424,112
Unsecured senior notes payable
4.50%
4.60
7/30/29
300,000
300,000
(805)
299,195
Unsecured senior notes payable
2.75%
2.87
12/15/29
400,000
400,000
(1,655)
398,345
Unsecured senior notes payable
4.70%
4.81
7/1/30
450,000
450,000
(1,686)
448,314
Unsecured senior notes payable
4.90%
5.05
12/15/30
700,000
700,000
(3,947)
696,053
Unsecured senior notes payable
3.375%
3.48
8/15/31
750,000
750,000
(3,704)
746,296
Unsecured senior notes payable
2.00%
2.12
5/18/32
900,000
900,000
(6,043)
893,957
Unsecured senior notes payable
1.875%
1.97
2/1/33
1,000,000
1,000,000
(6,240)
993,760
Unsecured senior notes payable
2.95%
3.07
3/15/34
800,000
800,000
(6,477)
793,523
Unsecured senior notes payable
4.75%
4.88
4/15/35
500,000
500,000
(4,500)
495,500
Unsecured senior notes payable
5.50%
5.66
10/1/35
550,000
550,000
(6,316)
543,684
Unsecured senior notes payable
5.25%
5.38
5/15/36
400,000
400,000
(3,767)
396,233
Unsecured senior notes payable
4.85%
4.93
4/15/49
300,000
300,000
(2,756)
297,244
Unsecured senior notes payable
4.00%
3.91
2/1/50
700,000
700,000
9,844
709,844
Unsecured senior notes payable
3.00%
3.08
5/18/51
850,000
850,000
(10,842)
839,158
Unsecured senior notes payable
3.55%
3.63
3/15/52
1,000,000
1,000,000
(13,228)
986,772
Unsecured senior notes payable
5.15%
5.26
4/15/53
500,000
500,000
(7,373)
492,627
Unsecured senior notes payable
5.625%
5.71
5/15/54
600,000
600,000
(6,470)
593,530
Unsecured debt weighted-average interest rate/
subtotal
3.91
650,000
350,000
425,000
700,000
1,503,500
8,850,000
12,478,500
(77,945)
12,400,555
Weighted-average interest rate/total
3.91%
$650,000
$350,000
$425,000
$700,000
$1,503,500
$8,850,000
$12,478,500
$(77,945)
$12,400,555
Balloon payments
$650,000
$350,000
$425,000
$700,000
$1,503,500
$8,850,000
$12,478,500
$
$12,478,500
Principal amortization
(77,945)
(77,945)
Total debt
$650,000
$350,000
$425,000
$700,000
$1,503,500
$8,850,000
$12,478,500
$(77,945)
$12,400,555
Fixed-rate debt
$650,000
$350,000
$425,000
$700,000
$1,150,000
$8,850,000
$12,125,000
$(77,606)
$12,047,394
Variable-rate debt
353,500
353,500
(339)
353,161
Total debt
$650,000
$350,000
$425,000
$700,000
$1,503,500
$8,850,000
$12,478,500
$(77,945)
$12,400,555
Weighted-average stated rate on maturing debt
4.03%
3.95%
3.95%
3.50%
4.71%
3.66%
(1)Represents the weighted-average interest rate as of the end of the applicable period, including amortization of loan fees, amortization of debt premiums (discounts), and other bank fees.
(2)Reflects any extension options that we control.
(3)Refer to footnotes 2 through 4 under “Fixed-rate and variable-rate debt” in “Summary of debt” for additional details.
(4)In January 2026, we repaid our 4.30% unsecured senior notes payable upon maturity. No gain or loss was incurred in connection with this repayment.
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Definitions and Reconciliations
December 31, 2025
This section contains additional details for sections throughout the Supplemental Information and the accompanying Earnings Press Release, as well as explanations and reconciliations of certain non-
GAAP financial measures and the reasons why we use these supplemental measures of performance and believe they provide useful information to investors. Additional detail can be found in our most recent
annual report on Form 10-K and subsequent quarterly reports on Form 10-Q, as well as other documents filed with or furnished to the SEC from time to time.
Adjusted EBITDA and Adjusted EBITDA margin
 
The following table reconciles net income (loss), the most directly comparable financial
measure calculated and presented in accordance with GAAP, to Adjusted EBITDA and calculates the
Adjusted EBITDA margin:
 
Three Months Ended
(Dollars in thousands)
12/31/25
9/30/25
6/30/25
3/31/25
12/31/24
Net (loss) income
$(995,354)
$(197,845)
$(62,189)
$38,662
$(16,095)
Interest expense
65,674
54,852
55,296
50,876
55,659
Income taxes
1,851
3,737
1,020
1,145
1,855
Depreciation and amortization
322,063
340,230
346,123
342,062
330,108
Stock compensation expense
8,232
10,293
12,530
10,064
12,477
Loss on early extinguishment of debt
107
Gain on sales of real estate
(619,914)
(9,366)
(13,165)
(101,806)
Unrealized (gains) losses on non-real estate
investments
(98,548)
(18,515)
21,938
68,145
79,776
Significant realized losses on non-real estate
investments
103,329
Impairment of real estate
1,717,188
323,870
129,606
32,154
186,564
Impairment of non-real estate investments
20,181
25,139
39,216
11,180
20,266
Increase (decrease) in provision for expected
credit losses on financial instruments
(341)
285
(434)
Adjusted EBITDA
$524,361
$532,502
$543,540
$541,408
$568,370
Total revenues
$754,414
$751,944
$762,040
$758,158
$788,945
Adjusted EBITDA margin
70%
71%
71%
71%
72%
We use Adjusted EBITDA as a supplemental performance measure of our operations, for
financial and operational decision-making, and as a supplemental means of evaluating period-to-period
comparisons on a consistent basis. Adjusted EBITDA is calculated as earnings before interest, taxes,
depreciation, and amortization (“EBITDA”), excluding stock compensation expense, gains or losses on
early extinguishment of debt, gains or losses on sales of real estate, impairments of real estate, changes
in provision for expected credit losses on financial instruments, and significant termination fees. Adjusted
EBITDA also excludes unrealized gains or losses and significant realized gains or losses and
impairments that result from our non-real estate investments. These non-real estate investment amounts
are classified in our consolidated statements of operations outside of total revenues.
We believe Adjusted EBITDA provides investors with relevant and useful information as it
allows investors to evaluate the operating performance of our business activities without having to
account for differences recognized because of investing and financing decisions related to our real
estate and non-real estate investments, our capital structure, capital market transactions, and variances
resulting from the volatility of market conditions outside of our control. For example, we exclude gains or
losses on the early extinguishment of debt to allow investors to measure our performance independent
of our indebtedness and capital structure. We believe that adjusting for the effects of impairments and
gains or losses on sales of real estate, significant impairments and realized gains or losses on non-real
estate investments, changes in provision for expected credit losses on financial instruments, and
significant termination fees allows investors to evaluate performance from period to period on a
consistent basis without having to account for differences recognized because of investing and financing
decisions related to our real estate and non-real estate investments or other corporate activities that
may not be representative of the operating performance of our properties.
In addition, we believe that excluding charges related to stock compensation and unrealized
gains or losses facilitates for investors a comparison of our business activities across periods without the
volatility resulting from market forces outside of our control. Adjusted EBITDA has limitations as a
measure of our performance. Adjusted EBITDA does not reflect our historical expenditures or future
requirements for capital expenditures or contractual commitments. While Adjusted EBITDA is a relevant
measure of performance, it does not represent net income (loss) or cash flows from operations
calculated and presented in accordance with GAAP, and it should not be considered as an alternative to
those indicators in evaluating performance or liquidity.
In order to calculate the Adjusted EBITDA margin, we divide Adjusted EBITDA by total
revenues as presented in our consolidated statements of operations. We believe that this supplemental
performance measure provides investors with additional useful information regarding the profitability of
our operating activities.
We are not able to forecast the net income of future periods without unreasonable effort and
therefore do not provide a reconciliation for Adjusted EBITDA on a forward-looking basis. This is due to
the inherent difficulty of forecasting the timing and/or amount of items that depend on market conditions
outside of our control, including the timing of dispositions, capital events, and financing decisions, as
well as quarterly components such as gain on sales of real estate, unrealized gains or losses on non-
real estate investments, impairments of real estate, impairments of non-real estate investments, and
changes in provision for expected credit losses on financial instruments. Our attempt to predict these
amounts may produce significant but inaccurate estimates, which would potentially be misleading for our
investors.
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Definitions and Reconciliations (continued)
December 31, 2025
Annual rental revenue
Annual rental revenue represents the annualized fixed base rental obligations, calculated in
accordance with GAAP. It includes the amortization of deferred revenue related to tenant-funded and
tenant-built landlord improvements for leases in effect as of the end of the period, related to our
operating RSF. Annual rental revenue is presented using 100% of the annual rental revenue from our
consolidated properties and our share of annual rental revenue for our unconsolidated real estate joint
ventures. Annual rental revenue per RSF is computed by dividing annual rental revenue by the sum of
100% of the RSF of our consolidated properties and our share of the RSF of properties held in
unconsolidated real estate joint ventures. As of December 31, 2025, approximately 92% of our leases
(on an annual rental revenue basis) were triple net leases, which require tenants to pay substantially all
real estate taxes, insurance, utilities, repairs and maintenance, common area expenses, and other
operating expenses (including increases thereto) in addition to base rent. Annual rental revenue
excludes these operating expenses recovered from our tenants. Amounts recovered from our tenants
related to these operating expenses, along with base rent, are classified in income from rentals in our
consolidated statements of operations.
Capitalization rates
Capitalization rates are calculated based on net operating income and net operating income
(cash basis) annualized, excluding lease termination fees, on stabilized operating assets for the quarter
preceding the date on which the property is sold, or near-term prospective net operating income.
Capitalized interest
We capitalize interest cost as a cost of a project during periods for which activities necessary
to develop, redevelop, or reposition a project for its intended use are ongoing, provided that
expenditures for the asset have been made and interest cost has been incurred. Activities necessary to
develop, redevelop, or reposition a project include pre-construction activities such as entitlements,
permitting, design, site work, and other activities preceding commencement of construction of
aboveground building improvements. The advancement of pre-construction efforts is focused on
reducing the time required to deliver projects to prospective tenants. These critical activities add
significant value for future ground-up development and are required for the vertical construction of
buildings. If we cease activities necessary to prepare a project for its intended use, interest costs related
to such project are expensed as incurred.
Cash interest
Cash interest is equal to interest expense calculated in accordance with GAAP plus
capitalized interest, less amortization of loan fees and debt premiums (discounts). Refer to the definition
of fixed-charge coverage ratio for a reconciliation of interest expense, the most directly comparable
financial measure calculated and presented in accordance with GAAP, to cash interest.
Class A/A+ properties and AAA locations
Class A/A+ properties are properties clustered in AAA locations that provide innovative
tenants with highly dynamic and collaborative environments that enhance their ability to successfully
recruit and retain world-class talent and inspire productivity, efficiency, creativity, and success. These
properties are typically well-located, professionally managed, and well-maintained, offering a wide range
of amenities and featuring premium construction materials and finishes. Class A/A+ properties are
generally newer or have undergone substantial redevelopment and are generally expected to command
higher annual rental rates compared to other classes of similar properties. AAA locations are in close
proximity to concentrations of specialized skills, knowledge, institutions, and related businesses. It is
important to note that our definition of property classification may not be directly comparable to other
equity REITs.
Credit ratings
Represents the credit ratings assigned by S&P Global Ratings or Moody’s Ratings as of
December 31, 2025. A credit rating is not a recommendation to buy, sell, or hold securities and may be
subject to revision or withdrawal at any time.
Development, redevelopment, and pre-construction
A key component of our business model is our disciplined allocation of capital to the
development and redevelopment of new Class A/A+ properties, as well as property enhancements
identified during the underwriting of certain acquired properties. These efforts are primarily concentrated
in collaborative Megacampus™ ecosystems within AAA life science innovation clusters, as well as other
strategic locations that support innovation and growth. These projects are generally focused on
providing high-quality, generic, and reusable spaces that meet the real estate requirements of a wide
range of tenants. Upon completion, each development or redevelopment project is expected to generate
increases in rental income, net operating income, and cash flows. Our development and redevelopment
projects are generally in locations that are highly desirable to high-quality entities, which we believe
results in higher occupancy levels, longer lease terms, higher rental income, higher returns, and greater
long-term asset value.
Development projects generally consist of the ground-up development of generic and
reusable laboratory facilities. Redevelopment projects consist of the permanent change in use of
acquired office, warehouse, or shell space into laboratory space. We generally will not commence new
development projects for aboveground construction of new Class A/A+ laboratory space without first
securing significant pre-leasing for such space, except when there is solid market demand for high-
quality Class A/A+ properties.
Pre-construction activities include entitlements, permitting, design, site work, and other
activities preceding commencement of construction of aboveground building improvements. The
advancement of pre-construction efforts is focused on reducing the time required to deliver projects to
prospective tenants. These critical activities add significant value for future ground-up development and
are required for the vertical construction of buildings. Ultimately, these projects will provide high-quality
facilities and are expected to generate significant revenue and cash flows.
Development, redevelopment, and pre-construction spending also includes the following
costs: (i) amounts to bring certain acquired properties up to market standard and/or other costs identified
during the acquisition process (generally within two years of acquisition) and (ii) permanent conversion
of space for highly flexible, move-in-ready laboratory space to foster the growth of promising early- and
growth-stage life science companies.
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Definitions and Reconciliations (continued)
December 31, 2025
Development, redevelopment, and pre-construction (continued)
Revenue-enhancing and repositioning capital expenditures represent spending to reposition
or significantly change the use of a property, including through improvement in the asset quality from
Class B to Class A/A+.
Non-revenue-enhancing capital expenditures represent costs required to maintain the current
revenues of a stabilized property, including the associated costs for renewed and re-leased space.
Dividend payout ratio (common stock)
Dividend payout ratio (common stock) is the ratio of the absolute dollar amount of dividends
on our common stock (shares of common stock outstanding on the respective record dates multiplied by
the related dividend per share) to funds from operations attributable to Alexandria’s common
stockholders – diluted, as adjusted.
Dividend yield
Dividend yield for the quarter represents the annualized quarter dividend divided by the
closing common stock price at the end of the quarter.
Space Intentionally Blank
Fixed-charge coverage ratio
Fixed-charge coverage ratio is a non-GAAP financial measure representing the ratio of
Adjusted EBITDA to cash interest and fixed charges. We believe that this ratio is useful to investors as a
supplemental measure of our ability to satisfy fixed financing obligations and preferred stock dividends.
Cash interest is equal to interest expense calculated in accordance with GAAP plus capitalized interest,
less amortization of loan fees and debt premiums (discounts).
The following table reconciles interest expense, the most directly comparable financial
measure calculated and presented in accordance with GAAP, to cash interest and computes fixed-
charge coverage ratio:
 
Three Months Ended
(Dollars in thousands)
12/31/25
9/30/25
6/30/25
3/31/25
12/31/24
Adjusted EBITDA
$524,361
$532,502
$543,540
$541,408
$568,370
Interest expense
$65,674
$54,852
$55,296
$50,876
$55,659
Capitalized interest
81,845
86,091
82,423
80,065
81,586
Amortization of loan fees
(4,481)
(4,505)
(4,615)
(4,691)
(4,620)
Amortization of debt discounts
(327)
(325)
(335)
(349)
(333)
Cash interest and fixed charges
$142,711
$136,113
$132,769
$125,901
$132,292
Fixed-charge coverage ratio:
– quarter annualized
3.7x
3.9x
4.1x
4.3x
4.3x
– trailing 12 months
4.0x
4.1x
4.3x
4.4x
4.5x
We are not able to forecast the net income of future periods without unreasonable effort and
therefore do not provide a reconciliation for fixed-charge coverage ratio on a forward-looking basis. This
is due to the inherent difficulty of forecasting the timing and/or amount of items that depend on market
conditions outside of our control, including the timing of dispositions, capital events, and financing
decisions, as well as quarterly components such as gain on sales of real estate, unrealized gains or
losses on non-real estate investments, impairments of real estate, impairments of non-real estate
investments, and changes in provision for expected credit losses on financial instruments. Our attempt
to predict these amounts may produce significant but inaccurate estimates, which would potentially be
misleading for our investors.
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Definitions and Reconciliations (continued)
December 31, 2025
Funds from operations and funds from operations, as adjusted, attributable to Alexandria’s
common stockholders
GAAP-basis accounting for real estate assets utilizes historical cost accounting and assumes
that real estate values diminish over time. In an effort to overcome the difference between real estate
values and historical cost accounting for real estate assets, the Nareit Board of Governors established
funds from operations as an improved measurement tool. Since its introduction, funds from operations
has become a widely used non-GAAP financial measure among equity REITs. We believe that funds
from operations is helpful to investors as an additional measure of the performance of an equity
REIT. Moreover, we believe that funds from operations, as adjusted, allows investors to compare our
performance to the performance of other real estate companies on a consistent basis, without having to
account for differences recognized because of real estate acquisition and disposition decisions,
financing decisions, capital structure, capital market transactions, variances resulting from the volatility
of market conditions outside of our control, or other corporate activities that may not be representative of
the operating performance of our properties.
The 2018 White Paper published by the Nareit Board of Governors (the “Nareit White Paper”)
defines funds from operations as net income (computed in accordance with GAAP), excluding gains or
losses on sales of real estate, and impairments of real estate, plus depreciation and amortization of
operating real estate assets, and after adjustments for our share of consolidated and unconsolidated
partnerships and real estate joint ventures. Impairments represent the write-down of assets when fair
value over the recoverability period is less than the carrying value due to changes in general market
conditions and do not necessarily reflect the operating performance of the properties during the
corresponding period.
We compute funds from operations, as adjusted, as funds from operations calculated in
accordance with the Nareit White Paper, excluding significant gains, losses, and impairments realized
on non-real estate investments, unrealized gains or losses on non-real estate investments, impairments
of real estate primarily consisting of right-of-use assets and pre-acquisition costs related to projects that
we decided to no longer pursue, gains or losses on early extinguishment of debt, changes in the
provision for expected credit losses on financial instruments, significant termination fees, acceleration of
stock compensation expense due to the resignations of executive officers, deal costs, the income tax
effect related to such items, and the amount of such items that is allocable to our unvested restricted
stock awards. We compute the amount that is allocable to our unvested restricted stock awards with
nonforfeitable dividends using the two-class method. Under the two-class method, we allocate net
income (after amounts attributable to noncontrolling interests) to common stockholders and to unvested
restricted stock awards with nonforfeitable dividends by applying the respective weighted-average
shares outstanding during each quarter-to-date and year-to-date period. This may result in a difference
of the summation of the quarter-to-date and year-to-date amounts. Neither funds from operations nor
funds from operations, as adjusted, should be considered as alternatives to net income (determined in
accordance with GAAP) as indications of financial performance, or to cash flows from operating
activities (determined in accordance with GAAP) as measures of liquidity, nor are they indicative of the
availability of funds for our cash needs, including our ability to make distributions.
We are not able to forecast the net income of future periods without unreasonable effort and
therefore do not provide a reconciliation for funds from operations on a forward-looking basis. This is
due to the inherent difficulty of forecasting the timing and/or amount of items that depend on market
conditions outside of our control, including the timing of dispositions, capital events, and financing
decisions, as well as components such as gain on sales of real estate, unrealized gains or losses on
non-real estate investments, impairments of real estate, impairments of non-real estate investments,
and changes in provision for expected credit losses on financial instruments. Our attempt to predict
these amounts may produce significant but inaccurate estimates, which would potentially be misleading
for our investors.
Funds from operations and funds from operations, as adjusted, attributable to Alexandria’s
common stockholders (continued)
The following table reconciles net income (loss) to funds from operations for the share of
consolidated real estate joint ventures attributable to noncontrolling interests and our share of
unconsolidated real estate joint ventures:
Noncontrolling Interest Share of
Consolidated Real Estate JVs
Our Share of Unconsolidated
Real Estate JVs
December 31, 2025
December 31, 2025
(In thousands)
Three Months
Ended
Year Ended
Three Months
Ended
Year Ended
Net income (loss)
$85,521
$212,844
$(304)
$(9,631)
Depreciation and amortization of real
estate assets
39,942
154,727
855
3,703
Gain on sale of real estate of
consolidated JV
(312,807)
(312,807)
Gain on sale of interest of
unconsolidated JV
(25)
(483)
Impairment of real estate
265,266
265,266
8,673
Funds from operations
$77,922
$320,030
$526
$2,262
Gross assets
Gross assets are calculated as total assets plus accumulated depreciation:
(In thousands)
12/31/25
9/30/25
6/30/25
3/31/25
12/31/24
Total assets
$34,081,835
$37,375,148
$37,623,629
$37,600,428
$37,527,449
Accumulated depreciation
6,127,525
6,416,745
6,146,378
5,886,561
5,625,179
Gross assets
$40,209,360
$43,791,893
$43,770,007
$43,486,989
$43,152,628
Incremental annual net operating income on development and redevelopment projects
Incremental annual net operating income represents the amount of net operating income, on
an annual basis, expected to be realized upon a project being placed into service and achieving full
occupancy. Incremental annual net operating income is calculated as the initial stabilized yield multiplied
by the project’s total cost at completion.
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Definitions and Reconciliations (continued)
December 31, 2025
Initial stabilized yield (unlevered)
Initial stabilized yield is calculated as the estimated amounts of net operating income at
stabilization divided by our investment in the property. For this calculation, we exclude any tenant-
funded and tenant-built landlord improvements from our investment in the property. Our initial stabilized
yield excludes the benefit of leverage. Our cash rents related to our development and redevelopment
projects are generally expected to increase over time due to contractual annual rent escalations. Our
estimates for initial stabilized yields, initial stabilized yields (cash basis), and total costs at completion
represent our initial estimates at the commencement of the project. We expect to update this information
upon completion of the project, or sooner if there are significant changes to the expected project yields
or costs.
Initial stabilized yield reflects rental income, including contractual rent escalations and any rent
concessions over the term(s) of the lease(s), calculated on a straight-line basis, and any
amortization of deferred revenue related to tenant-funded and tenant-built landlord improvements.
Initial stabilized yield (cash basis) reflects cash rents at the stabilization date after initial rental
concessions, if any, have elapsed and our total cash investment in the property.
Investment-grade or publicly traded large cap tenants
Investment-grade or publicly traded large cap tenants represent tenants that are investment-
grade rated or publicly traded companies with an average daily market capitalization greater than $10
billion for the twelve months ended December 31, 2025, as reported by Bloomberg Professional
Services. Credit ratings from Moody’s Ratings and S&P Global Ratings reflect credit ratings of the
tenant’s parent entity, and there can be no assurance that a tenant’s parent entity will satisfy the tenant’s
lease obligation upon such tenant’s default. We monitor the credit quality and related material changes
of our tenants. Material changes that cause a tenant’s market capitalization to decrease below $10
billion, which are not immediately reflected in the twelve-month average, may result in their exclusion
from this measure.
Space Intentionally Blank
Investments
We hold investments in publicly traded companies and privately held entities primarily
involved in the life science industry. We recognize, measure, present, and disclose these investments as
follows:
Statements of Operations
Balance Sheet
Gains and Losses
Carrying Amount
Unrealized
Realized
Difference between
proceeds received upon
disposition and historical
cost
Publicly traded
companies
Fair value
Changes in fair
value
Privately held entities
without readily
determinable fair
values that:
Report NAV
Fair value, using NAV
as a practical
expedient
Changes in NAV, as
a practical expedient
to fair value
Do not report NAV
Cost, adjusted for
observable price
changes and
impairments(1)
Observable price
changes(1)
Impairments to reduce costs
to fair value, which result in
an adjusted cost basis and
the differences between
proceeds received upon
disposition and adjusted or
historical cost
Equity method
investments
Contributions,
adjusted for our share
of the investee’s
earnings or losses,
less distributions
received, reduced by
other-than-temporary
impairments
Our share of
unrealized gains or
losses reported by
the investee
Our share of realized gains
or losses reported by the
investee, and other-than-
temporary impairments
(1)An observable price is a price observed in an orderly transaction for an identical or similar investment of the same
issuer. Observable price changes result from, among other things, equity transactions for the same issuer with
similar rights and obligations executed during the reporting period, including subsequent equity offerings or other
reported equity transactions related to the same issuer.
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Definitions and Reconciliations (continued)
December 31, 2025
Investments in real estate
The following table reconciles our investments in real estate as of December 31, 2025:
(In thousands)
Investments in
Real Estate
Gross investments in real estate
$34,817,521
Less: accumulated depreciation
(6,127,525)
Investments in real estate
$28,689,996
The following table presents our new Class A/A+ development and redevelopment pipeline,
excluding properties held for sale, as a percentage of gross assets and as a percentage of annual rental
revenue as of December 31, 2025:
Percentage of
(Dollars in thousands)
Book Value
Gross
Assets
Annual Rental
Revenue
Projects under active construction
$3,181,012
8%
—%
Future development projects(1) and land parcels primarily located in
Megacampuses
3,607,452
9
1
Total Class A/A+ development and redevelopment pipeline, excluding
properties held for sale
6,788,464
17
1
Properties held for sale – land parcels
261,208
1
Total Class A/A+ development and redevelopment pipeline
$7,049,672
18%
1%
(1)Includes projects with existing buildings that are generating or can generate operating cash flows. Also includes
development rights associated with existing operating campuses.
Space Intentionally Blank
Investments in real estate (continued)
The square footage presented in the table below is classified as operating as of December 31,
2025. These lease expirations or vacant space at recently acquired properties represent future
opportunities for which we have the intent, subject to market conditions and leasing, to commence first-
time conversion from non-laboratory space to laboratory space, or to commence future ground-up
development:
Dev/
Redev
RSF of Lease Expirations Targeted for
Development and Redevelopment
Property/Submarket
2026
2027
Thereafter(1)
Total
Under construction project:
Campus Point by Alexandria/University Town Center
Dev
52,620
52,620
Future projects:
446, 458, and 500 Arsenal Street/Cambridge/Inner
Suburbs
Dev
116,623
116,623
3000 Minuteman Road/Greater Boston
Redev
167,549
167,549
1122 and 1150 El Camino Real/South San Francisco
Dev
375,232
375,232
2100 and 2200 Geng Road/Greater Stanford
Dev
62,526
62,526
960 Industrial Road/Greater Stanford
Dev
112,590
112,590
Campus Point by Alexandria/University Town Center
Dev
96,805
96,805
Sequence District by Alexandria/Sorrento Mesa
Dev/
Redev
555,754
555,754
410 West Harrison Street/Elliott Bay
Dev
17,205
17,205
Other/Seattle
Dev
63,057
63,057
Canada
Redev
247,743
247,743
1,815,084
1,815,084
Total
52,620
1,815,084
1,867,704
(1)Includes vacant square footage as of December 31, 2025.
Space Intentionally Blank
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Definitions and Reconciliations (continued)
December 31, 2025
Joint venture financial information
We present components of balance sheet and operating results information related to our real
estate joint ventures, which are not presented, or intended to be presented, in accordance with GAAP.
We present the proportionate share of certain financial line items as follows: (i) for each real estate joint
venture that we consolidate in our financial statements, which are controlled by us through contractual
rights or majority voting rights, but of which we own less than 100%, we apply the noncontrolling interest
economic ownership percentage to each financial item to arrive at the amount of such cumulative
noncontrolling interest share of each component presented; and (ii) for each real estate joint venture that
we do not control and do not consolidate, which are instead controlled jointly or by our joint venture
partners through contractual rights or majority voting rights, we apply our economic ownership
percentage to each financial item to arrive at our proportionate share of each component presented.
The components of balance sheet and operating results information related to our real estate
joint ventures do not represent our legal claim to those items. For each entity that we do not wholly own,
the joint venture agreement generally determines what equity holders can receive upon capital events,
such as sales or refinancing, or in the event of a liquidation. Equity holders are normally entitled to their
respective legal ownership of any residual cash from a joint venture only after all liabilities, priority
distributions, and claims have been repaid or satisfied.
We believe that this information can help investors estimate the balance sheet and operating
results information related to our partially owned entities. Presenting this information provides a
perspective not immediately available from consolidated financial statements and one that can
supplement an understanding of the joint venture assets, liabilities, revenues, and expenses included in
our consolidated results.
The components of balance sheet and operating results information related to our real estate
joint ventures are limited as an analytical tool as the overall economic ownership interest does not
represent our legal claim to each of our joint ventures’ assets, liabilities, or results of operations. In
addition, joint venture financial information may include financial information related to the
unconsolidated real estate joint ventures that we do not control. We believe that in order to facilitate for
investors a clear understanding of our operating results and our total assets and liabilities, joint venture
financial information should be examined in conjunction with our consolidated statements of operations
and balance sheets. Joint venture financial information should not be considered an alternative to our
consolidated financial statements, which are presented and prepared in accordance with GAAP.
Space Intentionally Blank
Megacampus™
A Megacampus ecosystem is a cluster campus that consists of approximately 1 million RSF or
greater, including operating, active development/redevelopment, and land RSF less operating RSF
expected to be demolished. We consider Megacampuses that include a minimum of 750,000 operating
RSF to be Established Megacampuses. These Megacampuses have realized the scale and flexibility
that deliver strategic optionality to our tenants. We present certain metrics related to our Established
Megacampuses because we believe they facilitate a more robust understanding of certain of our
operating trends.
The following table reconciles our annual rental revenue and development and redevelopment
pipeline RSF, excluding properties classified as held for sale, as of December 31, 2025:
(Dollars in thousands)
Annual Rental
Revenue
Development and
Redevelopment
Pipeline RSF
Megacampus
$1,451,391
16,735,429
Core and non-core
410,665
4,867,151
Total
$1,862,056
21,602,580
Megacampus as a percentage of annual rental revenue and
of total development and redevelopment pipeline RSF
78%
77%
Net cash provided by operating activities after dividends
Net cash provided by operating activities after dividends is reduced by distributions to
noncontrolling interests, excludes liquidating distributions from asset sales, and excludes changes in
operating assets and liabilities as they represent timing differences.
Space Intentionally Blank
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Definitions and Reconciliations (continued)
December 31, 2025
Net debt and preferred stock to Adjusted EBITDA
Net debt and preferred stock to Adjusted EBITDA is a non-GAAP financial measure that we
believe is useful to investors as a supplemental measure of evaluating our balance sheet leverage. Net
debt and preferred stock is equal to the sum of total consolidated debt less cash, cash equivalents, and
restricted cash, plus preferred stock outstanding as of the end of the period. Refer to the definition of
Adjusted EBITDA and Adjusted EBITDA margin for further information on the calculation of Adjusted
EBITDA.
The following table reconciles debt to net debt and preferred stock and computes the ratio to
Adjusted EBITDA:
(Dollars in thousands)
12/31/25
9/30/25
6/30/25
3/31/25
12/31/24
Secured notes payable
$
$
$153,500
$150,807
$149,909
Unsecured senior notes payable
12,047,394
12,044,999
12,042,607
12,640,144
12,094,465
Unsecured senior line of credit and
commercial paper
353,161
1,548,542
1,097,993
299,883
Unamortized deferred financing costs
74,314
76,383
78,574
80,776
77,649
Cash and cash equivalents
(549,062)
(579,474)
(520,545)
(476,430)
(552,146)
Restricted cash
(4,693)
(4,705)
(7,403)
(7,324)
(7,701)
Preferred stock
Net debt and preferred stock
$11,921,114
$13,085,745
$12,844,726
$12,687,856
$11,762,176
Adjusted EBITDA:
– quarter annualized
$2,097,444
$2,130,008
$2,174,160
$2,165,632
$2,273,480
– trailing 12 months
$2,141,811
$2,185,820
$2,208,226
$2,218,722
$2,228,921
Net debt and preferred stock to Adjusted EBITDA:
– quarter annualized
5.7x
6.1x
5.9x
5.9x
5.2x
– trailing 12 months
5.6x
6.0x
5.8x
5.7x
5.3x
We are not able to forecast the net income of future periods without unreasonable effort and
therefore do not provide a reconciliation for net debt and preferred stock to Adjusted EBITDA on a
forward-looking basis. This is due to the inherent difficulty of forecasting the timing and/or amount of
items that depend on market conditions outside of our control, including the timing of dispositions,
capital events, and financing decisions, as well as quarterly components such as gain on sales of real
estate, unrealized gains or losses on non-real estate investments, impairments of real estate,
impairments of non-real estate investments, and changes in provision for expected credit losses on
financial instruments. Our attempt to predict these amounts may produce significant but inaccurate
estimates, which would potentially be misleading for our investors.
Net operating income, net operating income (cash basis), and operating margin
The following table reconciles net income (loss) to net operating income and net operating
income (cash basis) and computes operating margin:
Three Months Ended
Year Ended
(Dollars in thousands)
12/31/25
12/31/24
12/31/25
12/31/24
Net (loss) income
$(995,354)
$(16,095)
$(1,216,726)
$510,733
Equity in losses (earnings) of unconsolidated real
estate joint ventures
304
(6,635)
9,631
(7,059)
General and administrative expenses
28,020
32,730
117,047
168,359
Interest expense
65,674
55,659
226,698
185,838
Depreciation and amortization
322,063
330,108
1,350,478
1,202,380
Impairment of real estate
1,717,188
186,564
2,202,818
223,068
Loss on early extinguishment of debt
107
Gain on sales of real estate
(619,914)
(101,806)
(642,445)
(129,312)
Investment loss
3,890
67,988
56,343
53,122
Net operating income
521,871
548,513
2,103,951
2,207,129
Straight-line rent revenue
(14,096)
(17,653)
(73,476)
(143,329)
Amortization of deferred revenue related to tenant-
funded and -built landlord improvements
(5,264)
(1,214)
(14,771)
(1,543)
Amortization of acquired below-market leases
(5,889)
(15,512)
(37,763)
(85,679)
Provision for expected credit losses on financial
instruments
(341)
(434)
(56)
(434)
Net operating income (cash basis)
$496,281
$513,700
$1,977,885
$1,976,144
Net operating income (cash basis) annualized
$1,985,124
$2,054,800
$1,977,885
$1,976,144
Net operating income (from above)
$521,871
$548,513
$2,103,951
$2,207,129
Total revenues
$754,414
$788,945
$3,026,556
$3,116,394
Operating margin
69%
70%
70%
71%
Net operating income is a non-GAAP financial measure calculated as net income (loss), the
most directly comparable financial measure calculated and presented in accordance with GAAP,
excluding equity in the earnings of our unconsolidated real estate joint ventures, general and
administrative expenses, interest expense, depreciation and amortization, impairments of real estate,
gains or losses on early extinguishment of debt, gains or losses on sales of real estate, and investment
income or loss. We believe net operating income provides useful information to investors regarding our
financial condition and results of operations because it primarily reflects those income and expense
items that are incurred at the property level. Therefore, we believe net operating income is a useful
measure for investors to evaluate the operating performance of our consolidated real estate assets. Net
operating income on a cash basis is net operating income adjusted to exclude the effect of straight-line
rent, amortization of acquired above- and below-market lease revenue, amortization of deferred revenue
related to tenant-funded and tenant-built landlord improvements, and changes in the provision for
expected credit losses on financial instruments required by GAAP. We believe that net operating income
on a cash basis is helpful to investors as an additional measure of operating performance because it
eliminates straight-line rent revenue and the amortization of acquired above- and below-market leases
and tenant-funded and tenant-built landlord improvements.
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Definitions and Reconciliations (continued)
December 31, 2025
Net operating income, net operating income (cash basis), and operating margin (continued)
Furthermore, we believe net operating income is useful to investors as a performance
measure of our consolidated properties because, when compared across periods, net operating income
reflects trends in occupancy rates, rental rates, and operating costs, which provide a perspective not
immediately apparent from net income or loss. Net operating income can be used to measure the initial
stabilized yields of our properties by calculating net operating income generated by a property divided by
our investment in the property. Net operating income excludes certain components from net income in
order to provide results that are more closely related to the results of operations of our properties. For
example, interest expense is not necessarily linked to the operating performance of a real estate asset
and is often incurred at the corporate level rather than at the property level. In addition, depreciation and
amortization, because of historical cost accounting and useful life estimates, may distort comparability of
operating performance at the property level. Impairments of real estate have been excluded in deriving
net operating income because we do not consider impairments of real estate to be property-level
operating expenses. Impairments of real estate relate to changes in the values of our assets and do not
reflect the current operating performance with respect to related revenues or expenses. Our
impairments of real estate represent the write-down in the value of the assets to the estimated fair value
less cost to sell. These impairments result from investing decisions or a deterioration in market
conditions. We also exclude realized and unrealized investment gain or loss, which results from
investment decisions that occur at the corporate level related to non-real estate investments in publicly
traded companies and certain privately held entities. Therefore, we do not consider these activities to be
an indication of operating performance of our real estate assets at the property level. Our calculation of
net operating income also excludes charges incurred from changes in certain financing decisions, such
as losses on early extinguishment of debt and changes in provision for expected credit losses on
financial instruments, as these charges often relate to corporate strategy. Property operating expenses
included in determining net operating income primarily consist of costs that are related to our operating
properties, such as utilities, repairs, and maintenance; rental expense related to ground leases;
contracted services, such as janitorial, engineering, and landscaping; property taxes and insurance; and
property-level salaries. General and administrative expenses consist primarily of accounting and
corporate compensation, corporate insurance, professional fees, rent, and supplies that are incurred as
part of corporate office management. We calculate operating margin as net operating income divided by
total revenues.
We believe that in order to facilitate for investors a clear understanding of our operating
results, net operating income should be examined in conjunction with net income or loss as presented in
our consolidated statements of operations. Net operating income should not be considered as an
alternative to net income or loss as an indication of our performance, nor as an alternative to cash flows
as a measure of our liquidity or our ability to make distributions.
We are not able to forecast the net income of future periods without unreasonable effort and
therefore do not provide a reconciliation for net operating income on a forward-looking basis. This is due
to the inherent difficulty of forecasting the timing and/or amount of items that depend on market
conditions outside of our control, including the timing of dispositions, capital events, and financing
decisions, as well as components such as gain on sales of real estate, unrealized gains or losses on
non-real estate investments, impairments of real estate, impairments of non-real estate investments,
and changes in provision for expected credit losses on financial instruments. Our attempt to predict
these amounts may produce significant but inaccurate estimates, which would potentially be misleading
for our investors.
Operating statistics
We present certain operating statistics related to our properties, including number of
properties, RSF, occupancy percentage, leasing activity, and contractual lease expirations as of the end
of the period. We believe these measures are useful to investors because they facilitate an
understanding of certain trends for our properties. We compute the number of properties, RSF,
occupancy percentage, leasing activity, and contractual lease expirations at 100%, excluding RSF at
properties classified as held for sale, for all properties in which we have an investment, including
properties owned by our consolidated and unconsolidated real estate joint ventures. For operating
metrics based on annual rental revenue, refer to the definition of annual rental revenue herein.
Same property comparisons
As a result of changes within our total property portfolio during the comparative periods
presented, including changes from assets acquired or sold, properties placed into development or
redevelopment, and development or redevelopment properties recently placed into service, the
consolidated total income from rentals, as well as rental operating expenses in our operating results, can
show significant changes from period to period. In order to supplement an evaluation of our results of
operations over a given quarterly or annual period, we analyze the operating performance for all
consolidated properties that were fully operating for the entirety of the comparative periods presented,
referred to as same properties. We separately present quarterly and year-to-date same property results
to align with the interim financial information required by the SEC in our management’s discussion and
analysis of our financial condition and results of operations. These same properties are analyzed
separately from properties acquired subsequent to the first day in the earliest comparable quarterly or
year-to-date period presented, properties that underwent development or redevelopment at any time
during the comparative periods, unconsolidated real estate joint ventures, properties classified as held
for sale, and corporate entities (legal entities performing general and administrative functions), which are
excluded from same property results. Additionally, termination fees, if any, are excluded from the results
of same properties.
Space Intentionally Blank
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Definitions and Reconciliations (continued)
December 31, 2025
Same property comparisons (continued)
The following table reconciles the number of same properties to total properties for the year
ended December 31, 2025:
Redevelopment – placed into
Development – under construction
Properties
service after January 1, 2024
Properties
99 Coolidge Avenue
1
840 Winter Street
1
1450 Owens Street
1
Alexandria Center® for Advanced
Technologies – Monte Villa Parkway
6
10075 Barnes Canyon Road
1
421 Park Drive
1
7
4135 Campus Point Court
1
Acquisitions after January 1, 2024
Properties
701 Dexter Avenue North
1
Other
2
Campus Point by Alexandria
2
6
Unconsolidated real estate JVs
3
Development – placed into
Properties held for sale
20
service after January 1, 2024
Properties
Total properties excluded from same
properties
58
1150 Eastlake Avenue East
1
9810 Darnestown Road
1
Same properties
282
9820 Darnestown Road
1
Total properties in North America as of
December 31, 2025
340
4155 Campus Point Court
1
201 Brookline Avenue
1
9808 Medical Center Drive
1
230 Harriet Tubman Way
1
500 North Beacon Street and 4 Kingsbury
Avenue
2
10935, 10945, and 10955 Alexandria
Way
3
12
Redevelopment – under construction
Properties
40, 50, and 60 Sylvan Road
3
269 East Grand Avenue
1
8800 Technology Forest Place
1
311 Arsenal Street
1
Other
2
8
Stabilized occupancy date
The stabilized occupancy date represents the estimated date on which a development or
redevelopment project is expected to reach occupancy of 95% or greater.
Tenant recoveries
Tenant recoveries represent revenues comprising reimbursement of real estate taxes,
insurance, utilities, repairs and maintenance, common area expenses, and other operating expenses
and earned in the period during which the applicable expenses are incurred and the tenant’s obligation
to reimburse us arises.
We classify rental revenues and tenant recoveries generated through the leasing of real
estate assets within revenues in income from rentals in our consolidated statements of operations. We
provide investors with a separate presentation of rental revenues and tenant recoveries in “Same
property performance” in this Supplemental Information because we believe it promotes investors’
understanding of our operating results. We believe that the presentation of tenant recoveries is useful to
investors as a supplemental measure of our ability to recover operating expenses under our triple net
leases, including recoveries of utilities, repairs and maintenance, insurance, property taxes, common
area expenses, and other operating expenses, and of our ability to mitigate the effect to net income for
any significant variability to components of our operating expenses.
The following table reconciles income from rentals to tenant recoveries:
Three Months Ended
Year Ended
(In thousands)
12/31/25
9/30/25
6/30/25
3/31/25
12/31/24
12/31/25
12/31/24
Income from rentals
$728,872
$735,849
$737,279
$743,175
$763,249
$2,945,175
$3,049,706
Rental revenues
(538,330)
(541,070)
(553,377)
(552,112)
(566,535)
(2,184,889)
(2,304,339)
Tenant recoveries
$190,542
$194,779
$183,902
$191,063
$196,714
$760,286
$745,367
Total equity capitalization
Total equity capitalization is equal to the outstanding shares of common stock multiplied by the
closing price on the last trading day at the end of each period presented.
Total market capitalization
Total market capitalization is equal to the sum of total equity capitalization and total debt.
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Definitions and Reconciliations (continued)
December 31, 2025
Unencumbered net operating income as a percentage of total net operating income
Unencumbered net operating income as a percentage of total net operating income is a non-
GAAP financial measure that we believe is useful to investors as a performance measure of the results
of operations of our unencumbered real estate assets as it reflects those income and expense items that
are incurred at the unencumbered property level. Unencumbered net operating income is derived from
assets classified in continuing operations, which are not subject to any mortgage, deed of trust, lien, or
other security interest, as of the period for which income is presented.
The following table summarizes unencumbered net operating income as a percentage of total
net operating income:
 
Three Months Ended
(Dollars in thousands)
12/31/25
9/30/25
6/30/25
3/31/25
12/31/24
Unencumbered net operating income
$521,871
$512,710
$535,766
$530,691
$547,921
Encumbered net operating income
1,841
1,072
592
Total net operating income
$521,871
$512,710
$537,607
$531,763
$548,513
Unencumbered net operating income as a
percentage of total net operating income
100.0%
100.0%
99.7%
99.8%
99.9%
Weighted-average interest rate for capitalization of interest
The weighted-average interest rate required for calculating capitalization of interest pursuant
to GAAP represents a weighted-average rate as of the end of the applicable period, based on the rates
applicable to borrowings outstanding during the period, including expense/income related to interest rate
hedge agreements, amortization of loan fees, amortization of debt premiums (discounts), and other bank
fees. A separate calculation is performed to determine our weighted-average interest rate for
capitalization for each month. The rate will vary each month due to changes in variable interest rates,
outstanding debt balances, the proportion of variable-rate debt to fixed-rate debt, the amount and terms
of interest rate hedge agreements, and the amount of loan fee and premium (discount) amortization.
Space Intentionally Blank
Weighted-average shares of common stock outstanding – diluted
From time to time, we enter into capital market transactions, including forward equity sales
agreements (“Forward Agreements”), to fund acquisitions, to fund construction of our development and
redevelopment projects, and for general working capital purposes. While the Forward Agreements are
outstanding, we are required to consider the potential dilutive effect of our Forward Agreements under
the treasury stock method. Under this method, we also include the dilutive effect of unvested restricted
stock awards (“RSAs”) with forfeitable dividends in the calculation of diluted shares.
The weighted-average shares of common stock outstanding used in calculating EPS – diluted,
FFO per share – diluted, and FFO per share – diluted, as adjusted, during each period are calculated as
follows. Also shown are the weighted-average unvested shares associated with unvested RSAs with
nonforfeitable dividends used in calculating amounts allocable to these awards pursuant to the two-class
method for each of the respective periods presented below.
Three Months Ended
Year Ended
(In thousands)
12/31/25
9/30/25
6/30/25
3/31/25
12/31/24
12/31/25
12/31/24
Basic shares for earnings per
share
170,394
170,181
170,135
170,522
172,262
170,307
172,071
Unvested RSAs with
forfeitable dividends
Diluted shares for earnings
per share
170,394
170,181
170,135
170,522
172,262
170,307
172,071
Basic shares for funds from
operations per share and
funds from operations per
share, as adjusted
170,394
170,181
170,135
170,522
172,262
170,307
172,071
Unvested RSAs with
forfeitable dividends
110
124
57
77
83
Diluted shares for funds from
operations per share and
funds from operations per
share, as adjusted
170,504
170,305
170,192
170,599
172,262
170,390
172,071
Weighted-average unvested
RSAs with nonforfeitable
dividends used in
calculating the allocations
of net income, funds from
operations, and funds from
operations, as adjusted
1,570
1,917
1,998
2,053
2,417
1,883
2,779